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U.S. Department of Health and Human Services, National Institutes of Health

Drug Use and Addiction Research Programs

Federal program · program number 93.279 (the federal Assistance Listing number)

Key facts

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96 grants
Opening soon
11 grants
Type of help
Project grant, training
Typical award
Range-$5,724 to $27,502,167, Average-$621,479

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What it pays for

To support basic, clinical, translational, and implementation research in the field of substance use. To develop new knowledge and approaches for the prevention, diagnosis, and treatment of drug use, misuse, and addiction, drug overdose, and related health outcome, including HIV/AIDS. To support research training and research scientist development. To support dissemination of research findings. Small Business Innovation Research (SBIR) legislation is intended to expand and improve the SBIR programs to emphasize and increase private sector commercialization of technology developed through Federal SBIR research and development; increase small business participation in Federal research and development; and foster and encourage participation of socially and economically disadvantaged small business concerns and women-owned small business concerns in the SBIR program. The Small Business Technology Transfer (STTR) legistlation is intended to stimulate and foster scientific and technological innovation through cooperative research and development carried out between small business concerns and research institutions; foster technology transfer between small business concerns and research institutions; increase private sector commercialization of innovations derived from Federal research and development; and foster and encourage participation of socially and economically disadvantaged small business concerns and women-owned small business concerns in technological innovation.

Who can apply

In each year's official notice: Addressing Methodological Challenges with Clinical Trials of Rapid-Acting Psychotropic Interventional Drugs (RAPIDs) (R01 Clinical Trial Required)

How applications are judged

The following considerations will be used in determining projects to be funded: (1) Scientific and technical merit; (2) the feasibility of the research; (3) potential contribution to the national drug abuse problem; and (4) relevance to NIDA priorities. The following criteria will be used in considering the scientific and technical merit of SBIR/STTR Phase I grant applications: (1) The soundness and technical merit of the proposed approach; (2) the qualifications of the proposed principal investigator, supporting staff, and consultants; (3) the technological innovation of the proposed research; (4) the potential of the proposed research for commercial application; (5) the appropriateness of the budget requested; (6) the adequacy and suitability of the facilities and research environment; and (7) where applicable, the adequacy of assurances detailing the proposed means for (a) safeguarding human or animal subjects and/or (b) protecting against or minimizing any adverse effect on the environment. Phase II grant applications will be reviewed based upon the following criteria: (1) The degree to which the Phase I objectives were met and feasibility demonstrated; (2) the scientific and technical merit of the proposed approach for achieving the Phase II objectives; (3) the qualifications of the proposed principal investigator, supporting staff, and consultants; (4) the technology.

Match

None required (federal program listing).

Who in Tennessee has won this program

23 awards to Tennessee groups since 2016. Largest shown:

Past Tennessee winners
Past winnerWhereAmountFiscal year
Vanderbilt UniversityNashville$4.9M spent that year2025
State of TennesseeNashville$4.6M spent that year2025
Vanderbilt University Medical CenterNashville, Davidson County$4.5M2016
Vanderbilt University Medical CenterNashville, Davidson County$4.4M2023
Vanderbilt University Medical CenterNashville, Davidson County$4.2M spent that year2025
Vanderbilt University Medical CenterNashville, Davidson County$4M2022
University of TennesseeMemphis, Shelby County$3.9M2017
Meharry Medical CollegeNashville, Davidson County$3.7M2022
University of TennesseeKnoxville, Knox County$3.5M2019
University of TennesseeMemphis, Shelby County$3.4M2021
University of TennesseeMemphis, Shelby County$3.1M2019
St Jude Children's Research Hospital IncMemphis, Shelby County$3.1M2022

Source: Federal Audit Clearinghouse, USAspending.gov.

Tennessee groups that got this money through a state agency or another organization

This federal money also reaches local groups as pass-through grants. 42 pass-through grants on file. Largest shown:

Tennessee pass-through grant winners
Past winnerWhereThroughAmountFiscal year
Vanderbilt University Medical CenterNashville, Davidson CountyVanderbilt University$1.2M spent that year2025
State of TennesseeNashvilleUniversity of California, San Diego$397K spent that year2023
Ut-Battelle LLCOak Ridge, Anderson CountyResearch Triangle Institute$368K2023
Vanderbilt UniversityNashvilleDenovx, LLC$366K spent that year2024
St Jude Children's Research Hospital IncMemphis, Shelby CountyUniversity of Kentucky Research Foundation, the$361K2023
Ut-Battelle LLCOak Ridge, Anderson CountyResearch Triangle Institute$345K2023
Ut-Battelle LLCOak Ridge, Anderson CountyResearch Triangle Institute$345K2024
Ut-Battelle LLCOak Ridge, Anderson CountyResearch Triangle Institute$344K2024
Ut-Battelle LLCOak Ridge, Anderson CountyResearch Triangle Institute$319K2024
Ut-Battelle LLCOak RidgeResearch Triangle Institute$319K2026
Ut-Battelle LLCOak RidgeResearch Triangle Institute$319K2026
Vanderbilt University Medical CenterNashville, Davidson CountyMeharry Medical College$291K spent that year2025

Source: USAspending.gov pass-through reports (the first recipient reports each one of $30,000 or more).

Official program listing (SAM.gov) Program website