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National Institutes of Health · Department of Health and Human Services

Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional)

Open · Opportunity PAR-25-101 · Assistance Listing 93.279

Key facts

Deadline
Due Aug 11, 2027 · 309 days left
Award size
Up to $150K
Total available
$150K
Cost share / match ?
Not required
Who can apply
County government, Public college or university, Other (see eligibility), Small business, Tribal organization, School district, Tribal government, State government, Special district (utility, fire, etc.), City or town government, Nonprofit with 501(c)(3), Private college or university, Larger business, Nonprofit without 501(c)(3)
Where
Anywhere in the U.S., including Tennessee

Before you apply: federal grants require an active SAM.gov registration (Unique Entity ID) and a Grants.gov account. Registration is free but can take weeks, so start now, not when the deadline is close. Grant-ready checklist

How this fits you

  • Available in Tennessee (nationwide program)
  • No cost share required
  • Tennessee recipients since 2023: 19

Tell us who you are to see whether you're eligible.

More from National Institutes of Health

Read the official notice View on Grants.gov Add deadline to my calendar Sign in to save

About this grant

The National Institute on Drug Abuse (NIDA) Cutting-Edge Basic Research Award (CEBRA) is designed to foster highly innovative or conceptually creative research related to the etiology, pathophysiology, prevention, or treatment of substance use disorders (SUDs). It supports high-risk and potentially high-impact research that is sparse or not included in NIDA's current portfolio that has the potential to transform SUD research. The proposed research should: 1. develop, and/or adapt, revolutionary techniques or methods for addiction research or that show promising future applicability to SUD research; and /or 2. test an innovative and significant hypothesis for which there are scant precedent or preliminary data and which, if confirmed, would transform current thinking.

Eligibility (from the notice)

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Who in Tennessee has won this program

19 awards to Tennessee recipients in 4 counties since federal FY2023. Largest shown:

Past Tennessee recipients
RecipientWhereAmountFY
Vanderbilt University Medical CenterNashville, Davidson County$4.5M2016
Vanderbilt University Medical CenterNashville, Davidson County$4.4M2023
Vanderbilt University Medical CenterNashville, Davidson County$4M2022
University Of TennesseeMemphis, Shelby County$3.9M2017
Meharry Medical CollegeNashville, Davidson County$3.7M2022
University Of TennesseeKnoxville, Knox County$3.5M2019
University Of TennesseeMemphis, Shelby County$3.4M2021
University Of TennesseeMemphis, Shelby County$3.1M2019
St Jude Children'S Research Hospital IncMemphis, Shelby County$3.1M2022
University Of TennesseeMemphis, Shelby County$3.1M2022
University Of TennesseeMemphis, Shelby County$3M2023
Vanderbilt University Medical CenterNashville, Davidson County$2.9M2019

Source: USAspending.gov. Past awards show who this program funds; they don't guarantee future awards.

About the program (93.279)

Drug Use and Addiction Research Programs

How applications are judged

The following considerations will be used in determining projects to be funded: (1) Scientific and technical merit; (2) the feasibility of the research; (3) potential contribution to the national drug abuse problem; and (4) relevance to NIDA priorities. The following criteria will be used in considering the scientific and technical merit of SBIR/STTR Phase I grant applications: (1) The soundness and technical merit of the proposed approach; (2) the qualifications of the proposed principal investigator, supporting staff, and consultants; (3) the technological innovation of the proposed research; (4) the potential of the proposed research for commercial application; (5) the appropriateness of the budget requested; (6) the adequacy and suitability of the facilities and research environment; and (7) where applicable, the adequacy of assurances detailing the proposed means for (a) safeguarding human or animal subjects and/or (b) protecting against or minimizing any adverse effect on the environment. Phase II grant applications will be reviewed based upon the following criteria: (1) The degree to which the Phase I objectives were met and feasibility demonstrated; (2) the scientific and technical merit of the proposed approach for achieving the Phase II objectives; (3) the qualifications of the proposed principal investigator, supporting staff, and consultants; (4) the technology.

Matching requirements

This program has no statutory formula. Matching requirements are not applicable to this assistance listing. MOE requirements are not applicable to this assistance listing.

Examples of funded projects

Not Applicable.

Program listing on SAM.gov

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