National Institutes of Health · Department of Health and Human Services
BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Specialized Projects for Scalable Technologies (U01 Clinical Trial Not Allowed)
Key facts
- Deadline
- Due Oct 4, 2027 · 362 days left
- Award size
- Not specified — see notice
- Total available
- $10M
- Cost share / match ?
- Not required · Work out your budget and match
- Who can apply
- County government, School district, Tribal government, Nonprofit with 501(c)(3), Private college or university, Tribal organization, Other (see eligibility), City or town government, Larger business, Nonprofit without 501(c)(3), Special district (utility, fire, etc.), State government, Small business, Public college or university
- Where
- Anywhere in the U.S., including Tennessee
Before you apply: federal grants require an active SAM.gov registration (Unique Entity ID) and a Grants.gov account. Registration is free but can take weeks, so start now, not when the deadline is close. Grant-ready checklist
How this fits you
- Available in Tennessee (nationwide program)
- No cost share required
- Past Tennessee awards on file: 412
Tell us who you are to see whether you're eligible.
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Official notice: https://simpler.grants.gov/opportunity/6219f5d0-0978-4477-8a3f-13d2c43d8c55 · Printed from grantme.click/grants/72a44e85-6291-4695-b44b-296988a77fde
Read the official notice View on Grants.gov Add deadline to my calendar Sign in to save
About this grant
This funding announcement, issued by the Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative, seeks transformative, cutting-edge, and innovative research that embraces new technologies, ideas, and approaches to understand brain circuit function and contributions to behavior. It is a component of the BRAIN Initiative Connectivity Across Scales (BRAIN CONNECTS) Program, which aims to lay the scientific foundation for the next generation of neural circuit-based approaches for preventing and treating devastating brain disorders.This Notice of Funding Opportunity (NOFO) supports Specialized Projects to develop current or emerging technologies to generate comprehensive atlases of brain connectivity, with an emphasis on human, non-human primate (NHP), and mouse. Projects using other species are also permitted, if their use is well justified and the goal is to test and validate approaches that can be generalized across species. Applications may address any aspect(s) of brain connectivity and associated data pipelines, including data collection, reconstruction, analysis, integration, dissemination, and interpretation, to enable faster, more precise, and more cost-effective generation and interpretation of brain-wide wiring diagrams. Funded projects will be integrated into the BRAIN CONNECTS Network consisting of projects funded under this and preceding BRAIN CONNECTS NOFOs, as a coordinated effort aimed at developing the capabilities to generate wiring diagrams that can span entire brains across multiple scales.
Eligibility (from the notice)
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility. Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Should we apply? (2-minute check) Ask a partner for a letter
Your schedule, working back from the deadline
- Oct7
Check that your SAM.gov registration is active (or start it now)
Grants.gov: allow up to 10 business days for SAM registration, weeks or months if information isn't verified. It must be renewed every year. Grants.gov - Sep13
Ask partners for letters of support or commitment
Suggested: partners need time to write and sign letters. - Sep27
Finish a complete draft for a final review
University grant offices require final versions about 5 business days before the sponsor deadline. Emory Office of Sponsored Programs - Oct2
Submit
Grants.gov: submit at least 24–48 hours before the deadline: uploads fail, systems slow down, errors need fixing. Grants.gov blog - Oct4
Deadline
From the funder.
Save this grant to put these dates in your tracker and private calendar.
Who in Tennessee has won this program
199 awards to Tennessee recipients in 4 counties since 1977. Largest shown:
| Recipient | Where | Amount | FY |
|---|---|---|---|
| Vanderbilt University Medical Center | Nashville, Davidson County | $37.5M | 2021 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $24.1M | 2011 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $18.6M | 2024 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $18.3M | 2019 |
| St Jude Children'S Research Hospital Inc | Memphis, Shelby County | $14.9M | 2015 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $14M | 1997 |
| Vanderbilt University | Nashville, Davidson County | $12.7M | 2021 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $10.1M | 1977 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $10M | 2025 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $9.5M | 2020 |
| Vanderbilt University | Nashville, Davidson County | $9.4M | 1997 |
| Vanderbilt University | Nashville, Davidson County | $8.7M | 2001 |
Source: USAspending.gov. Past awards show who this program funds; they don't guarantee future awards.
Tennessee groups that got this money through a state agency or another grantee
This federal money also reaches local groups as subawards. 213 subawards on file. Largest shown:
| Recipient | Where | Through | Amount | FY |
|---|---|---|---|---|
| Vanderbilt University Medical Center | Nashville, Davidson County | University of Vermont & State Agricultural College | $4.4M | 2023 |
| University Of Tennessee | Memphis, Shelby County | Virginia Polytechnic Institute & State University | $1.8M | 2023 |
| Vanderbilt University | Nashville, Davidson County | Yale Univ | $1.6M | 2023 |
| Vanderbilt University Medical Center | Nashville, Davidson County | The Trustees of Princeton University | $1.6M | 2023 |
| Vanderbilt University Medical Center | Nashville, Davidson County | Regents of the University of Michigan | $1.4M | 2024 |
| St Jude Children'S Research Hospital Inc | Memphis, Shelby County | The University of Texas Southwestern Medical Center | $1.4M | 2026 |
| Vanderbilt University Medical Center | Nashville, Davidson County | University of California, San Diego | $1.3M | 2024 |
| Vanderbilt University Medical Center | Nashville, Davidson County | University of Texas Health Science Center At Houston | $1.2M | 2026 |
| Vanderbilt University | Nashville, Davidson County | The Pennsylvania State University | $1.1M | 2026 |
| Vanderbilt University | Nashville, Davidson County | Vanderbilt University Medical Center | $1.1M | 2023 |
| Vanderbilt University Medical Center | Nashville, Davidson County | Mayo Clinic | $1M | 2026 |
| Vanderbilt University | Nashville, Davidson County | University of Pittsburgh - of the Commonwealth System of Higher Education | $1M | 2023 |
Source: USAspending.gov subaward reports (prime recipients report subawards of $30,000 or more).
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Matching requirements
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The following considerations will be used in determining projects to be funded: (1) Scientific and technical merit of the proposal; (2) program balance; and (3) relevance to NIAAA priorities and public health issues. The following criteria will be used in considering the scientific and technical merit of SBIR/STTR Phase I grant applications: (1) The soundness and technical merit of the proposed approach; (2) the qualifications of the proposed principal investigator, supporting staff, and consultants; (3) the technological innovation of the proposed research; (4) the potential of the proposed research for commercial application; (5) the appropriateness of the budget requested; (6) the adequacy and suitability of the facilities and research environment; and (7) where applicable, the adequacy of assurances detailing the proposed means for (a) safeguarding human of animal subjects, and/or (b) protecting against or minimizing any adverse effect on the environment. Phase II grant applications will be reviewed based upon the following criteria: (1) The degree to which Phase I objectives were met and feasibility demonstrated; (2) the scientific and technical merit of the proposed approach for achieving the Phase II objectives; (3) the qualifications of the proposed principal investigator, supporting staff, and consultants; (4) the technological innovation, originality, or societal importance of the proposed research; (5) the potential of the proposed research for commercial...
Matching requirements
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Matching requirements
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Matching requirements
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Matching requirements
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Matching requirements
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Matching requirements
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Matching requirements are not applicable to this assistance listing.
MOE requirements are not applicable to this assistance listing.
Examples of funded projects
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Matching requirements
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Matching requirements are not applicable to this assistance listing.
MOE requirements are not applicable to this assistance listing.
Examples of funded projects
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Matching requirements
This program has no statutory formula.
Matching requirements are not applicable to this assistance listing.
MOE requirements are not applicable to this assistance listing.
Examples of funded projects
Not Applicable.