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U.S. Department of Health and Human Services, National Institutes of Health

Diabetes, Digestive, and Kidney Diseases Extramural Research

Federal program · program number 93.847 (the federal Assistance Listing number)

Key facts

Open now
55 grants
Opening soon
18 grants
Type of help
Project grant
Typical award
Project Grants: Range of $1,300 to $10,834,000; $418,000 average NRSAs: Range of $2,500 to $869,000; $116,000 average SBIR: Range of $6,500 to $2,074,000; $585,000 average
Deadlines
Contact the headquarters or regional location, as appropriate for application deadlines

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What it pays for

(1) To promote extramural basic and clinical biomedical research that improves the understanding of the mechanisms underlying disease and leads to improved preventions, diagnosis, and treatment of diabetes, digestive, and kidney diseases. Programmatic areas within the National Institute of Diabetes and Digestive and Kidney Diseases include diabetes, digestive, endocrine, hematologic, liver, metabolic, nephrologic, nutrition, obesity, and urologic diseases. Specific programs areas of interest include the following: (a) For diabetes, endocrine, and metabolic diseases areas: Fundamental and clinical studies including the etiology, pathogenesis, prevention, diagnosis, treatment and cure of diabetes mellitus and its complications; Normal and abnormal function of the pituitary, thyroid, parathyroid, adrenal, and other hormone secreting glands; Hormonal regulation of bone, adipose tissue, and liver; on fundamental aspects of signal transduction, including the action of hormones, coregulators, and chromatin remodeling proteins; Hormone biosynthesis, secretion, metabolism, and binding; and on hormonal regulation of gene expression and the role(s) of selective receptor modulators as partial agonists or antagonists of hormone action; and Fundamental studies relevant to metabolic disorders including membrane structure, function, and transport phenomena and enzyme biosynthesis; and basic and clinical studies on the etiology, pathogenesis, prevention, and treatment of inherited metabolic disorders (such as cystic fibrosis). (b) For digestive disease and nutrition areas: Genetics and...

Who can apply

Project Grants: Universities, colleges, medical, dental and nursing schools, schools of public health, laboratories, hospitals, State and local health departments, other public or private institutions, both non-profit and for-profit, and individuals who propose to establish, expand, and improve research activities in health sciences and related fields. NRSAs: Support is provided for academic and research training only, in health and health-related areas that are periodically specified by the National Institutes of Health. To be eligible, predoctoral awardees must have completed the baccalaureate degree and postdoctoral awardees must have a professional or scientific degree (M.D., Ph.D., D.D.S., D.O., D.V.M., Sc.D., D.Eng., or equivalent domestic or foreign degree). Individuals must be nominated and sponsored by a public or nonprofit private institution having staff and facilities appropriate to the proposed research training program. All awardees must be citizens or have been admitted to the United States for permanent residence. Nonprofit domestic organizations may apply for the Institutional NRSA. SBIR and STTR grants can be awarded only to domestic small businesses that meet the following criteria: 1) Is independently owned and operated, is not dominant in the field of operation in which it is proposing, has a place of business in the United States and operates primarily...

How applications are judged

The major elements in evaluating proposals include assessments of: (1) The scientific merit and general significance of the proposed study and its objectives; (2) the technical adequacy of the experimental design and approach; (3) the competency of the proposed investigator or group to successfully pursue the project; (4) the adequacy of the available and proposed facilities and resources; (5) the necessity of the budget components requested in relation to the proposed project; and (6) the relevance and importance to announced program objectives. The following criteria will be used in considering the scientific and technical merit of SBIR/STTR Phase I grant applications: (1) The soundness and technical merit of the proposed approach; (2) the qualifications of the proposed principal investigator, supporting staff, and consultants; (3) the technological innovation of the proposed research; (4) the potential of the proposed research for commercial application; (5) the appropriateness of the budget requested; (6) the adequacy and suitability of the facilities and research environment; and (7) where applicable, the adequacy of assurances detailing the proposed means for (a) safeguarding human or animal subjects, and/or (b) protecting against or minimizing any adverse effect on the environment. Phase II grant applications will be reviewed based upon the following criteria: (1) The degree to which the Phase I objectives were met and feasibility demonstrated; (2) the scientific...

Match

None required (federal program listing).

Who in Tennessee has won this program

26 awards to Tennessee groups since 1975 · 0 in Hamilton County. Largest shown:

Past Tennessee winners
Past winnerWhereAmountFiscal year
Vanderbilt University Medical CenterNashville, Davidson County$44.1M spent that year2025
Vanderbilt University Medical CenterNashville, Davidson County$23M2023
Vanderbilt University Medical CenterNashville, Davidson County$23M2001
Vanderbilt University Medical CenterNashville, Davidson County$12.4M1986
Vanderbilt UniversityNashville, Davidson County$12.2M1978
Vanderbilt UniversityNashville$12.2M spent that year2025
Vanderbilt University Medical CenterNashville, Davidson County$12.1M2012
Vanderbilt UniversityNashville, Davidson County$11.5M1998
Vanderbilt University Medical CenterNashville, Davidson County$8.5M2005
Vanderbilt University Medical CenterNashville, Davidson County$7.7M2005
Vanderbilt University Medical CenterNashville, Davidson County$7.7M2003
Vanderbilt University Medical CenterNashville, Davidson County$6.9M1994

Source: Federal Audit Clearinghouse, USAspending.gov.

Tennessee groups that got this money through a state agency or another organization

This federal money also reaches local groups as pass-through grants. 143 pass-through grants on file · 0 in Hamilton County. Largest shown:

Tennessee pass-through grant winners
Past winnerWhereThroughAmountFiscal year
Vanderbilt University Medical CenterNashville, Davidson CountyUniversity of California, Los Angeles$1.7M2025
Vanderbilt UniversityNashvilleVumc$1.5M spent that year2024
Vanderbilt University Medical CenterNashville, Davidson CountyUniversity of Pennsylvania$1.4M spent that year2025
Vanderbilt UniversityNashvilleVanderbilt University Medical Center$1.3M spent that year2025
Vanderbilt University Medical CenterNashville, Davidson CountyRegents of the University of Michigan$1.1M2023
Vanderbilt University Medical CenterNashville, Davidson CountyUniversity of Utah$967K2023
Vanderbilt University Medical CenterNashville, Davidson CountyRegents of the University of Michigan$866K2024
Vanderbilt University Medical CenterNashville, Davidson CountyTrustees of the University of Pennsylvania, the$778K2024
Vanderbilt University Medical CenterNashville, Davidson CountyTrustees of the University of Pennsylvania, the$778K2025
Vanderbilt University Medical CenterNashville, Davidson CountyTrustees of the University of Pennsylvania, the$778K2023
Vanderbilt University Medical CenterNashville, Davidson CountyIcahn School of Medicine at Mount Sinai$732K2024
Vanderbilt University Medical CenterNashville, Davidson CountyTrustees of the University of Pennsylvania, the$726K2026

Source: USAspending.gov pass-through reports (the first recipient reports each one of $30,000 or more).

Official program listing (SAM.gov) Program website