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National Institutes of Health · Department of Health and Human Services

Single Source for the Continuation of the Physiology of the Weight Reduced State (POWERS) Study (U01- Clinical Trials Required)

Opening soon

Key facts

Deadline
The funder's estimated date (Jul 1, 2026) has passed. Check the official notice Estimate, not confirmed by the funder ?
Award size
Not stated: see the official notice
Match ?
Not required · Work out your budget and match
Who can apply
Set by the official notice: see Who can apply below
Where
Anywhere in the U.S., including Tennessee

Opening soon: the funder has announced this grant, but you can't apply yet. Use the time to get ready and check whether it fits.

Before you apply: federal grants require an active SAM.gov registration (Unique Entity ID) and a Grants.gov account. Registration is free but can take weeks, so start now, not when the deadline is close. Get-ready checklist

How this fits you

  • Available in Hamilton County (nationwide program)
  • No match required
  • Past Tennessee awards on file: 41

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About this grant

The purpose of this NOFO is to continue the Physiology of the Weight Reduced State (POWERS) study. The goal of POWERS is to understand the physiological processes underlying individual variability in weight regain following weight loss. The continuation of POWERS will allow for the completion of the clinical trial and analysis of data and biospecimens.

Who can apply, from the official notice

NIDDK requests a Single Source competition for the Continuation of the Physiology of the Weight Reduced State (POWERS) Study at the University of Pittsburgh.

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Writing the need statement? Hamilton County facts with citations.

Who in Tennessee has won this program

20 awards to Tennessee groups in 1 county since 1975 · 0 in Hamilton County. Largest shown:

Past Tennessee winners
Past winnerWhereAmountFiscal year
Vanderbilt University Medical CenterNashville, Davidson County$23M2023
Vanderbilt University Medical CenterNashville, Davidson County$23M2001
Vanderbilt University Medical CenterNashville, Davidson County$12.4M1986
Vanderbilt UniversityNashville, Davidson County$12.2M1978
Vanderbilt University Medical CenterNashville, Davidson County$12.1M2012
Vanderbilt UniversityNashville, Davidson County$11.5M1998
Vanderbilt University Medical CenterNashville, Davidson County$8.5M2005
Vanderbilt University Medical CenterNashville, Davidson County$7.7M2005
Vanderbilt University Medical CenterNashville, Davidson County$7.7M2003
Vanderbilt University Medical CenterNashville, Davidson County$6.9M1994
Vanderbilt University Medical CenterNashville, Davidson County$6.7M2013
Vanderbilt University Medical CenterNashville, Davidson County$6.7M2017

Source: USAspending.gov. Past awards show who this program funds. They don't guarantee future awards.

Tennessee groups that got this money through a state agency or another organization

This federal money also reaches local groups as pass-through grants. 21 pass-through grants on file · 0 in Hamilton County. Largest shown:

Tennessee pass-through grant winners
Past winnerWhereThroughAmountFiscal year
Vanderbilt University Medical CenterNashville, Davidson CountyUniversity of California, Los Angeles$1.7M2025
Vanderbilt University Medical CenterNashville, Davidson CountyRegents of the University of Michigan$1.1M2023
Vanderbilt University Medical CenterNashville, Davidson CountyUniversity of Utah$967K2023
Vanderbilt University Medical CenterNashville, Davidson CountyRegents of the University of Michigan$866K2024
Vanderbilt University Medical CenterNashville, Davidson CountyTrustees of the University of Pennsylvania, the$778K2024
Vanderbilt University Medical CenterNashville, Davidson CountyTrustees of the University of Pennsylvania, the$778K2023
Vanderbilt University Medical CenterNashville, Davidson CountyTrustees of the University of Pennsylvania, the$778K2025
Vanderbilt University Medical CenterNashville, Davidson CountyIcahn School of Medicine at Mount Sinai$732K2024
Vanderbilt University Medical CenterNashville, Davidson CountyTrustees of the University of Pennsylvania, the$726K2026
Vanderbilt University Medical CenterNashville, Davidson CountyThe General Hospital Corporation$567K2023
Vanderbilt University Medical CenterNashville, Davidson CountyVanderbilt University Medical Center$497K2023
Vanderbilt UniversityNashville, Davidson CountyUniversity of Kansas Medical Center Research Institute, Inc.$485K2025

Source: USAspending.gov pass-through reports (the first recipient reports each one of $30,000 or more).

About the federal program

Diabetes, Digestive, and Kidney Diseases Extramural Research
Program number 93.847 (the federal Assistance Listing number) · U.S. Department of Health and Human Services, National Institutes of Health · Project grant

How applications are judged

The major elements in evaluating proposals include assessments of: (1) The scientific merit and general significance of the proposed study and its objectives; (2) the technical adequacy of the experimental design and approach; (3) the competency of the proposed investigator or group to successfully pursue the project; (4) the adequacy of the available and proposed facilities and resources; (5) the necessity of the budget components requested in relation to the proposed project; and (6) the relevance and importance to announced program objectives. The following criteria will be used in considering the scientific and technical merit of SBIR/STTR Phase I grant applications: (1) The soundness and technical merit of the proposed approach; (2) the qualifications of the proposed principal investigator, supporting staff, and consultants; (3) the technological innovation of the proposed research; (4) the potential of the proposed research for commercial application; (5) the appropriateness of the budget requested; (6) the adequacy and suitability of the facilities and research environment; and (7) where applicable, the adequacy of assurances detailing the proposed means for (a) safeguarding human or animal subjects, and/or (b) protecting against or minimizing any adverse effect on the environment. Phase II grant applications will be reviewed based upon the following criteria: (1) The degree to which the Phase I objectives were met and feasibility demonstrated; (2) the scientific...

Match

None required (federal program listing).

This program on SAM.gov

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Source: Federal grants from Grants.gov · the official federal record. Last checked by GrantMe Oct 7, 2026.

Reference numbers: official notice number RFA-DK-27-122 · program number 93.847