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U.S. Department of Health and Human Services, National Institutes of Health

Cancer Cause and Prevention Research

Federal program · program number 93.393 (the federal Assistance Listing number)

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49 grants
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9 grants
Type of help
Cooperative agreement (a grant with close agency involvement), project grant
Typical award
Range: $927 to $3,046,580 Average: $568,686

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What it pays for

To identify cancer risks and risk reduction strategies, to identify factors that cause cancer in humans, and to discover and develop mechanisms for cancer prevention and preventive interventions in humans. Research programs include: (1) chemical, physical and molecular carcinogenesis; (2) screening, early detection and risk assessment, including biomarker discovery, development and validation; (3) epidemiology; (4) nutrition and bioactive food components; (5) immunology and vaccines; (6) field studies and statistics; (7) cancer chemoprevention and interception; (8) pre-clinical and clinical agent development; (9) organ site studies and clinical trials; (10) health-related quality of life and patient-centered outcomes; and (11) supportive care and management of symptoms and toxicities. Small Business Innovation Research (SBIR) program: To expand and improve the SBIR program; to stimulate technical innovation; to increase private sector commercialization of innovations derived from Federal research and development funding; to increase small business participation in Federal research and development; and to foster and encourage participation in innovation and entrepreneurship by women and socially/economically disadvantaged persons. Small Business Technology Transfer (STTR) program: To stimulate and foster scientific and technological innovation through cooperative research and development carried out between small business concerns and research institutions; to foster technology transfer through cooperative research and development between small business concerns and...

Who can apply

The awardee will be a university, college, hospital, public agency, nonprofit research institution or for-profit organization that submits an application and receives a grant or cooperative agreement for support of research by a named principal investigator. SBIR grants can be awarded only to domestic small businesses (entities that are independently owned and operated for profit, are not dominant in the field in which research is proposed, and have no more than 500 employees). Primary employment (more than one- half time) of the principal investigator must be with the small business at the time of award and during the conduct of the proposed project. In both Phase I and Phase II, the research must be performed in the U.S. and its possessions. To be eligible for funding, a grant application must be approved for scientific merit and program relevance by a scientific review group and a national advisory council. STTR grants can be awarded only to domestic small business concern (entities that are independently owned and operated for profit, are not dominant in the field in which research is proposed and have no more than 500 employees) which "partner" with a research institution in cooperative research and development. At least 40 percent of the project is to be performed by the small business concern and at least 30 percent by the research institution. In both Phase I and...

How applications are judged

The major elements in evaluating proposals include assessments of: (1) The scientific merit and general significance of the proposed study and its objectives; 2) the technical adequacy of the experimental design and approach; (3) the competency of the proposed investigator or group to successfully pursue the project; (4) the adequacy of the available and proposed facilities and resources; (5) the necessity of the budget components requested in relation to the proposed project; and (6) the relevance and importance to announced program objectives. The following criteria will be used in considering the scientific and technical merit of SBIR/STTR Phase I grant applications: (1) The soundness and technical merit of the proposed approach; (2) the qualifications of the proposed principal investigator, supporting staff, and consultants; (3) the technological innovation of the proposed research; (4) the potential of the proposed research for commercial application; (5) the appropriateness of the budget requested; (6) the adequacy and suitability of the facilities and research environment; and (7) where applicable, the adequacy of assurances detailing the proposed means for (a) safeguarding human or animal subjects, and/or (b) protecting against or minimizing any adverse effect on the environment. Phase II grant applications will be reviewed based upon the following criteria: (1) The degree to which the Phase I objectives were met and feasibility demonstrated; (2) the scientific...

Match

None required (federal program listing).

Who in Tennessee has won this program

16 awards to Tennessee groups since 1981 · 0 in Rhea County. Largest shown:

Past winnerWhereAmountFiscal year
Vanderbilt University Medical CenterNashville, Davidson County$14.4M spent that year2025
St. Jude Children's Research Hospital, Inc.Memphis, Shelby County$14.2M spent that year2025
Vanderbilt University Medical CenterNashville, Davidson County$14M2016
Vanderbilt UniversityNashville, Davidson County$14M1997
Vanderbilt University Medical CenterNashville, Davidson County$11.1M1981
Vanderbilt University Medical CenterNashville, Davidson County$9.8M2023
Vanderbilt University Medical CenterNashville, Davidson County$8.6M2021
St Jude Children's Research Hospital IncMemphis, Shelby County$6M2025
St Jude Children's Research Hospital IncMemphis, Shelby County$5.1M2013
Baptist Memorial Hospital-TiptonCovington, Tipton County$4.8M2013
Vanderbilt University Medical CenterNashville, Davidson County$4.2M2025
Vanderbilt UniversityNashville, Davidson County$3.9M2016

Source: Federal Audit Clearinghouse, USAspending.gov.

Tennessee groups that got this money through a state agency or another organization

This federal money also reaches local groups as pass-through grants. 123 pass-through grants on file · 0 in Rhea County. Largest shown:

Past winnerWhereThroughAmountFiscal year
Vanderbilt University Medical CenterNashville, Davidson CountyHealth Research, Inc.$1.3M2025
St Jude Children's Research Hospital IncMemphis, Shelby CountyOhio State University, the$1M2023
St Jude Children's Research Hospital IncMemphis, Shelby CountyThe General Hospital Corporation$663K2023
Vanderbilt University Medical CenterNashville, Davidson CountyOhio State University, the$568K2024
Vanderbilt University Medical CenterNashville, Davidson CountyUniversity of Texas Health Science Center at Houston$519K2024
St Jude Children's Research Hospital IncMemphis, Shelby CountyBaylor College of Medicine$507K2026
St Jude Children's Research Hospital IncMemphis, Shelby CountyWashington University, the$415K2025
St. Jude Children's Research Hospital, Inc.Memphis, Shelby CountyNorthwestern University$393K spent that year2025
State of TennesseeNashvilleUniversity of Utah$373K spent that year2025
Meharry Medical CollegeNashville, Davidson CountyVanderbilt University Medical Center$369K2023
St Jude Children's Research Hospital IncMemphis, Shelby CountyNorthwestern University$350K2023
St Jude Children's Research Hospital IncMemphis, Shelby CountyNorthwestern University$350K2024

Source: USAspending.gov pass-through reports (the first recipient reports each one of $30,000 or more).

Official program listing (SAM.gov) Program website