U.S. Department of Health and Human Services, National Institutes of Health
Research Infrastructure Programs
Key facts
Open now
- NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) · Due Apr 5, 2027 · 180 days left
- NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional) · Due Apr 5, 2027 · 180 days left
- Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed) · Due May 7, 2027 · 212 days left
- Change of Recipient Organization (Type 7 Parent Clinical Trial Optional) · Due Jul 12, 2027 · 278 days left
- Successor-in-Interest (Type 6 Parent Clinical Trial Optional) · Due Jul 17, 2027 · 283 days left
- Screening and Functional Validation of Genomic Variants Associated with Human Congenital Anomalies (R01 Clinical Trial Not Allowed) · Due Jan 7, 2028 · 457 days left
- NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) · Due Jan 7, 2028 · 457 days left
- Development of Animal Models and Related Biological Materials for Research (R21 Clinical Trial Not Allowed) · Due Jan 7, 2028 · 457 days left
- Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) · Due Jan 7, 2028 · 457 days left
- Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32) · Due May 4, 2028 · 575 days left
- Ruth L. Kirschstein National Research Service Award (NRSA) Short-Term Institutional Research Training Grant (Parent T35) · Due May 7, 2028 · 578 days left
- INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed) · Due Jun 15, 2028 · 617 days left
- INCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome (R21 Clinical Trial Not Allowed) · Due Jun 15, 2028 · 617 days left
- Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed) · Due Jul 1, 2028 · 633 days left
- Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed) · Due Jul 1, 2028 · 633 days left
- Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed) · Due Aug 25, 2028 · 688 days left
- Animal and Biological Material Resource Centers (P40 Clinical Trial Not Allowed) · Due Sep 26, 2028 · 720 days left
- Resource-Related Research Projects for Development of Models and Related Materials for Studying Human Health and Diseases (R24 Clinical Trials Not Allowed) · Due Sep 28, 2028 · 722 days left
- Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional) · Due Nov 30, 2028 · 785 days left
- Limited Competition: Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed) · Due Jan 26, 2029 · 842 days left
- SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional) · Due Apr 5, 2029 · 911 days left
- NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional) · Due Apr 5, 2029 · 911 days left
Opening soon
Announced, but you can't apply yet. Get ready now.
- Research Resource for a National Swine Resource and Research Center (U42 Clinical Trial Not Allowed) · Opens Nov 25, 2026 · due about Jan 25, 2027 Estimate, not confirmed by the funder
- National Biomedical Research Centers (P50 Clinical Trial Optional) · Opens Nov 25, 2026 · due about Jan 25, 2027 Estimate, not confirmed by the funder
- Integrated Specific Pathogen Free Research Models and Human New Approach Methodologies to Advance HIV/AIDS Research (U42 Clinical Trial Not Allowed) · Opens Nov 24, 2026 · due about Jan 25, 2027 Estimate, not confirmed by the funder
- Small Instruments and Modern Equipment for Shared-use Biomedical Research Facilities and Resources (S15 Clinical Trial Not Allowed) · Opens Jul 27, 2027 · due about Sep 27, 2027 Estimate, not confirmed by the funder
- Development of Models, New Approach Methodologies, and Biological Materials for Studying Human Health and Diseases (R21 Clinical Trial Not Allowed) · Opens Dec 16, 2027 · due about Feb 16, 2028 Estimate, not confirmed by the funder
What it pays for
The Office of Research Infrastructure Programs (ORIP) is a program office in the Division of Program Coordination, Planning, and Strategic Initiatives (DPCPSI) dedicated to supporting research infrastructure and related research resource programs. ORIP consists of the Division of Comparative Medicine (DCM) and the Division of Construction and Instruments (DCI).
Who can apply
Institutions of higher education, hospitals, and other institutions and organizations, both nonprofit and for-profit, seeking to establish, continue, or enlarge programs consistent with the objectives of the program. To be eligible for instrumentation and equipment programs, applications must be Private nonprofit institutions/organizations, Public nonprofit institutions/organizations. Applicants for NRSA must be citizens of the United States or be admitted to the United States for permanent residency. Applicants must be nominated and sponsored by a public or private nonprofit institution with staff and facilities suitable for the proposed research training. Nonprofit domestic organizations may apply for the institutional NRSA. Research Career Development: Applications may be submitted on behalf of candidates by domestic, nonfederal organizations, public or private institutions of higher education.
How applications are judged
The major elements in evaluating proposals include assessments of: (1) The scientific merit and general significance of the proposed study and its objectives; (2) the technical adequacy of the experimental design and approach; (3) the competency of the proposed investigator or group to successfully pursue the project; (4) the adequacy of the available and proposed facilities and resources; (5) the necessity of the budget components requested in relation to the proposed project; and (6) the relevance and importance to announced program objectives. The major elements in evaluating proposals for scientific instruments include assessments of (1) the need for the instruments; (2) technical expertise in the requested technology; (3) advancements of research projects when the novel technology is available; (4) administration of the usage of the instrument and (5) institutional support for the long term maintenance and the usage of the instrument.
Match
None required (federal program listing).
Who in Tennessee has won this program
30 awards to Tennessee groups since 2019. Largest shown:
| Past winner | Where | Amount | Fiscal year |
|---|---|---|---|
| Vanderbilt University | Nashville | $2.6M spent that year | 2025 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $2M | 2019 |
| Vanderbilt University | Nashville, Davidson County | $2M | 2021 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $2M | 2021 |
| Vanderbilt University | Nashville, Davidson County | $2M | 2024 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $2M | 2025 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $1.9M | 2025 |
| Vanderbilt University | Nashville, Davidson County | $1.6M | 2022 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $1.3M spent that year | 2025 |
| Vanderbilt University | Nashville, Davidson County | $1.3M | 2026 |
| Oak Ridge Associated Universities, Incorporated | Oak Ridge | $1.1M spent that year | 2025 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $857K | 2023 |
Source: Federal Audit Clearinghouse, USAspending.gov.
Tennessee groups that got this money through a state agency or another organization
This federal money also reaches local groups as pass-through grants. 6 pass-through grants on file. Largest shown:
| Past winner | Where | Through | Amount | Fiscal year |
|---|---|---|---|---|
| Vanderbilt University | Nashville | Vumc | $1.4M spent that year | 2024 |
| Vanderbilt University | Nashville, Davidson County | Vanderbilt University Medical Center | $857K | 2023 |
| Vanderbilt University | Nashville, Davidson County | Vanderbilt University Medical Center | $597K | 2023 |
| Vanderbilt University | Nashville, Davidson County | Oregon Health & Science University | $75K | 2023 |
| Vanderbilt University | Nashville | Vanderbilt University Medical Center | $60K spent that year | 2025 |
| Vanderbilt University | Nashville | Oregon Health & Science University | — spent that year | 2024 |
Source: USAspending.gov pass-through reports (the first recipient reports each one of $30,000 or more).