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U.S. National Science Foundation

NSF Small Business Innovation Research / Small Business Technology Transfer Phase I, Phase II, Fast-Track Programs: A Pilot Emphasis on Scientific Instrumentation

Open

Key facts

Deadline
Due Nov 4, 2026 · 28 days left
Award size
Not stated: see the official notice
Total available
$40M · about 86 awards
Match ?
Not required · Work out your budget and match
Who can apply
Set by the official notice: see Who can apply below
Where
Anywhere in the U.S., including Tennessee

Before you apply: federal grants require an active SAM.gov registration (Unique Entity ID) and a Grants.gov account. The deadline is in 28 days. If your registration isn't already active, it may not be ready in time, so check it today. Get-ready checklist

How this fits you

  • Available in Tennessee (nationwide program)
  • No match required
  • Past Tennessee awards on file: 67

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About this grant

NSF invests in scientific discoveries, technological breakthroughs, and transformative innovations that strengthen economic growth, enhance security, and improve the lives of Americans and people around the world. Our ability to support that mission requires a robust scientific and engineering (S&E) enterprise in the United States that allows scientists to innovate at the frontier. In addition to funding scientists, America needs next-generation scientific instrumentation that allows scientists to pursue new innovations. In many fields, it is critical that this new scientific instrumentation is developed in the United States. In support of this mission, NSF is initiating a pilot emphasis area for its SBIR/STTR programs to invest in startups and small businesses that are specifically developing enabling technologies that include next-generation instrumentation, novel experimental platforms, and other scientific equipment to advance the frontiers of scientific discovery and strengthen the American scientific and engineering enterprise. This encompasses novel instrumentation necessary for the coming era of AI-driven discoveries. This pilot will prioritize investing in the necessary infrastructure to support entirely new fields of scientific discovery, making new technological breakthroughs and transformative applications possible. Through this approach, NSF will continue to lead in propelling the scientific enterprise to new frontiers. This pilot emphasis area for the NSF SBIR/STTR programs funds across enabling technology areas and market sectors in alignment with the above goals; the programs do not solicit specific technologies for the purpose of procuring goods and services for the agency from startups and small businesses. NSF will continue to invest in other deep-tech ventures through the historic NSF SBIR/STTR programs available here. Funding opportunities are available through the NSF SBIR/STTR programs: Phase I, Phase II, Fast-Track, and Supplements. Each company can receive up to $2.0 million for R&D. Separately, NSF welcomes Strategic Breakthrough proposals, upon recommendation from the Program Officer, for Phase II awardees. NSF takes no equity and awardees keep full ownership of their company and intellectual property. Expanding Participation in STEM and Gold Standard Science: NSF prioritizes cutting-edge discovery science and engineering...

Who can apply, from the official notice

*Who May Serve as PI: Who May Serve as PI: The primary employment of the Principal Investigator (PI) must be with the small business at the time of award and for the duration of the award, unless a new PI is named. Primary employment is defined as at least 51 percent employed by the small business. NSF normally considers a full-time work week to be 40 hours and considers employment elsewhere greater than 19.6 hours per week to conflict with this requirement. Occasionally, deviations from this requirement may occur, and must be approved in writing by the Funding Agreement program officer after consultation with the agency SBIR/STTR program manager/coordinator. The PI must have a legal right to work for the proposing company in the United States, as evidenced by citizenship, permanent residency, or an appropriate visa. The PI does not need to be associated with an academic institution. There are no PI degree requirements (i.e., the PI is not required to hold a Ph.D. or any other degree). A PI must devote a minimum of one calendar month of effort per six months of performance to an NSF SBIR/STTR Phase I project. The PI must devote the following levels of effort: For Phase I: a minimum of one calendar month per six months of performance For Phase II: a minimum of one calendar month per six months of performance For Fast-Track: a minimum of three calendar months per six months of performance.

Ask a partner for a letter

Your schedule, working back from the deadline

  1. Oct7
    Check that your SAM.gov registration is active (or start it now)
    Grants.gov: allow up to 10 business days for SAM registration, weeks or months if information isn't verified. It must be renewed every year. Grants.gov
  2. Oct14
    Ask partners for letters of support or commitment
    Suggested: partners need about three weeks to write and sign letters.
  3. Oct28
    Finish a complete draft for a final review
    Suggested: leave about a week for someone else to read the draft.
  4. Nov2
    Submit
    Grants.gov: submit at least 24–48 hours before the deadline: uploads fail, systems slow down, errors need fixing. Grants.gov blog
  5. Nov4
    Deadline
    From the funder.

Save this grant to put these dates in My grants and your private calendar.

Who in Tennessee has won this program

29 awards to Tennessee groups in 6 counties since 2017. Largest shown:

Past Tennessee winners
Past winnerWhereAmountFiscal year
Vanderbilt UniversityNashville, Davidson County$15M2023
University of TennesseeKnoxville, Knox County$5M2026
Vanderbilt UniversityNashville, Davidson County$5M2022
Vanderbilt UniversityNashville$3.7M spent that year2025
Winter Innovations, Inc.Knoxville, Knox County$1.7M2024
Skynano LLCKnoxville, Knox County$1.7M2022
Crosslink Composites, Inc.Harriman, Roane County$1.6M2022
Fibarcode, LLCKnoxville, Knox County$1.6M2025
Muzology LLCNashville, Davidson County$1.4M2020
Neurodyne, IncGermantown, Shelby County$1.3M2023
University of TennesseeChattanooga, Hamilton County$1.3M2026
Fc Renew, LLCKnoxville, Knox County$1.2M2025

Source: USAspending.gov, Federal Audit Clearinghouse. Past awards show who this program funds. They don't guarantee future awards.

Tennessee groups that got this money through a state agency or another organization

This federal money also reaches local groups as pass-through grants. 38 pass-through grants on file. Largest shown:

Tennessee pass-through grant winners
Past winnerWhereThroughAmountFiscal year
University of TennesseeKnoxville, Knox CountyHudsonalpha Institute for Biotechnology$1.7M2026
Aglaunch InitiativeMemphis, Shelby CountyNorth Dakota State University$703K2026
University of TennesseeKnoxville, Knox CountyUniversity of California Irvine$423K2025
University of TennesseeKnoxville, Knox CountyUniversity of California Irvine$366K2026
Co Lab theChattanoogaUniversity of Tennessee$328K2026
Chattanooga Quantum CollaborativeChattanooga, Hamilton CountyUniversity of Tennessee$320K2026
Fisk UniversityNashville, Davidson CountyGeorgia Tech Research Corporation$312K2024
Fisk UniversityNashville, Davidson CountyUniversity Corporation for Advanced Internet Development$286K2025
University of TennesseeKnoxville, Knox CountyUniversity of Alabama$255K2025
Tennessee State UniversityNashville, Davidson CountyUniversity of Tennessee$250K2023
Tennessee State UniversityNashville, Davidson CountyUniversity Corporation for Advanced Internet Development$250K2023
Board of Regents TennesseeNashville, Davidson CountyUniversity of Tennessee$245K2023

Source: USAspending.gov pass-through reports (the first recipient reports each one of $30,000 or more).

About the federal program

Technology, Innovation, and Partnerships, also called “NSF Directorate for Technology, Innovation, and Partnerships (TIP)”
Program number 47.084 (the federal Assistance Listing number) · National Science Foundation · Grant

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None required (federal program listing).

This program on SAM.gov

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Source: Federal grants from Grants.gov · the official federal record. Last checked by GrantMe Oct 7, 2026.

Reference numbers: official notice number 26-511 · program number 47.084