Find grants

23 grants for “Breakthrough”

Closing: this week (1) · this month (2) · next 3 months (6)
  1. Federal

    Leading Edge Acceleration Projects for Health IT (LEAP)

    Office of the National Coordinator · Department of Health and Human Services · Opening soon

    Deadline
    Opening date not announced Estimate, not confirmed by the funder
    Award
    Amount not specified
    • Available in Tennessee (nationwide program)
    • No match required

    This Notice of Funding Opportunity (NOFO) seeks Leading Edge Acceleration Projects (LEAP) in Health Information Technology (Health IT) to address well-documented and fast emerging challenges inhibiting the development, use, and/or advancement of...

    Checked today against the source

  2. Federal

    NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)

    National Institutes of Health · Department of Health and Human Services · Open

    Deadline
    Due Apr 5, 2029 · 910 days left
    Award
    Amount not specified
    • Available in Tennessee (nationwide program)
    • Needs a match (see how much in the notice)
    • Past Tennessee awards on file: 1893

    The NIH Phase IIB Strategic Breakthrough award bridges the funding gap between the end of a Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Phase II award and commercialization. The Phase IIB Strategic Breakthrough...

    Checked today against the source

  3. Federal

    DoW Breast Cancer, Breakthrough Award Levels 1 and 2

    Defense Health Agency Contracting Activity - DHACA · Department of Defense · Open

    Deadline
    Due Nov 18, 2026 · 41 days left
    Award
    Amount not specified
    • Available in Tennessee (nationwide program)
    • No match required
    • Past Tennessee awards on file: 115

    Summary: The fiscal year 2026 (FY26) Breast Cancer Research Program (BCRP) Breakthrough Award mechanism supports promising research with high potential to lead to or make breakthroughs in breast cancer. All applications must address at least one of the...

    Checked today against the source

  4. Federal

    Mathematical Foundations of Artificial Intelligence (MFAI)

    U.S. National Science Foundation · Open

    Deadline
    Due Oct 9, 2026 · 1 day left
    Award
    $500K – $1.5M
    • Available in Tennessee (nationwide program)
    • No match required
    • Only 1 day left to apply
    • Past Tennessee awards on file: 260

    Machine Learning and Artificial Intelligence (AI) are enabling extraordinary scientific breakthroughs in fields ranging from protein folding, natural language processing, drug synthesis, and recommender systems to the discovery of novel engineering...

    Checked today against the source

  5. Federal

    NSF Small Business Innovation Research / Small Business Technology Transfer Phase I, Phase II, Fast-Track Programs: A Pilot Emphasis on Scientific Instrumentation

    U.S. National Science Foundation · Open

    Deadline
    Due Nov 4, 2026 · 27 days left
    Award
    Amount not specified
    • Available in Tennessee (nationwide program)
    • No match required
    • Past Tennessee awards on file: 67

    NSF invests in scientific discoveries, technological breakthroughs, and transformative innovations that strengthen economic growth, enhance security, and improve the lives of Americans and people around the world. Our ability to support that mission...

    Checked today against the source

  6. Federal

    Postdoctoral Research Fellowships in Biology (PRFB)

    U.S. National Science Foundation · Open

    Deadline
    Due Sep 28, 2027 · 355 days left
    Award
    From $220K
    • Available in Tennessee (nationwide program)
    • No match required
    • Past Tennessee awards on file: 74

    The integration of Artificial Intelligence (AI) and Biological Research has the potential to pave the way for breakthroughs in biotechnology and bio-system design that will create innovations, new industries, and jobs. To capitalize on this promise, the...

    Checked today against the source

  7. Federal

    NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)

    National Institutes of Health · Department of Health and Human Services · Open

    Deadline
    Due Jan 7, 2028 · 456 days left
    Award
    Amount not specified
    • Available in Tennessee (nationwide program)
    • No match required
    • Past Tennessee awards on file: 2071

    The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a...

    Checked today against the source

  8. Federal

    SBIR/STTR Commercialization Readiness Pilot (CRP) Program (Parent SB1 Clinical Trial Optional)

    National Institutes of Health · Department of Health and Human Services · Open

    Deadline
    Due Apr 5, 2029 · 910 days left
    Award
    Amount not specified
    • Available in Tennessee (nationwide program)
    • No match required
    • Past Tennessee awards on file: 2303

    The Commercialization Readiness Pilot (CRP) program helps small business concerns (SBCs) move NIH-funded SBIR or STTR projects from late-stage development to commercialization. The CRP supports later-stage research and development (R&D) and/or technical...

    Checked today against the source

  9. Federal

    NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)

    National Institutes of Health · Department of Health and Human Services · Open

    Deadline
    Due Jan 7, 2028 · 456 days left
    Award
    Amount not specified
    • Available in Tennessee (nationwide program)
    • No match required
    • Past Tennessee awards on file: 2253

    The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a...

    Checked today against the source

  10. Federal

    Fiscal Year (FY) 2027 Department of War (DoW) Multidisciplinary Research Program of the University Research Initiative (MURI)

    Dept of the Army -- Materiel Command · Department of Defense · Open

    Deadline
    Due Apr 9, 2027 · 183 days left
    Award
    Up to $7.5M
    • Available in Tennessee (nationwide program)
    • No match required
    • Past Tennessee awards on file: 60

    Army Research Office (ARO): DoW's MURI program addresses high-risk basic research and attempts to understand or achieve something that has never been done before. The program was initiated 40 years ago and it has regularly produced significant scientific...

    Checked today against the source

  11. Federal

    Computational and Data-Enabled Science and Engineering

    U.S. National Science Foundation · Open

    Deadline
    No deadline listed: see the official notice
    Award
    Amount not specified
    • Available in Tennessee (nationwide program)
    • No match required
    • Past Tennessee awards on file: 129

    Large-scale simulations and the ability to accumulate massive amounts of data have revolutionized science and engineering. The goal of the Computational and Data-enabled Science and Engineering (CDS&E) meta-program is to identify and capitalize on...

    Checked today against the source

  12. Federal

    Maximizing Investigators’ Research Award (MIRA) for Early Stage Investigators (ESI)

    National Institutes of Health · Department of Health and Human Services · Open

    Deadline
    Due Feb 6, 2029 · 852 days left
    Award
    Amount not specified
    • Available in Tennessee (nationwide program)
    • No match required
    • Past Tennessee awards on file: 115

    The Maximizing Investigators' Research Award (MIRA) for Early Stage Investigators (ESIs) provides support for ESIs with a program of research that aligns with the NIGMS mission.MIRA distributes funding among promising investigators across the country. The...

    Checked today against the source

  13. Federal

    Genomic and Biologic Therapies for ADRD (U01 Clinical Trial Optional)

    National Institutes of Health · Department of Health and Human Services · Opening soon

    Deadline
    Due about Nov 10, 2026 Estimate, not confirmed by the funder
    Award
    Amount not specified
    • Available in Tennessee (nationwide program)
    • No match required
    • Past Tennessee awards on file: 106

    The National Institutes of Neurological Disorders and Stroke (NINDS) is interested in supporting research projects proposing the optimization and translational development of genomic and biologic therapeutic candidates for Alzheimer’s Disease-Related...

    Checked today against the source

  14. Federal

    INCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome (R21 Clinical Trial Not Allowed)

    National Institutes of Health · Department of Health and Human Services · Open

    Deadline
    Due Jun 15, 2028 · 616 days left
    Award
    Up to $200K
    • Available in Tennessee (nationwide program)
    • No match required
    • Past Tennessee awards on file: 1329

    The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. This Notice of Funding Opportunity (NOFO) invites researchers...

    Checked today against the source

  15. Federal

    Center for Foundational Academic Research and Strategic Innovation for the Defense Enterprise (C-FARSIDE)

    Washington Headquarters Services · Department of Defense · Closed for this year

    Deadline
    Next round: about Jul 16 – Aug 17, 2027 Estimate, not confirmed by the funder
    Award
    $50M – $150M
    • Available in Tennessee (nationwide program)
    • No match required
    • Past Tennessee awards on file: 53

    Bridging foundational academic research and strategic innovation for the Defense enterprise, the Center for Foundational Academic Research and Strategic Innovation for the Defense Enterprise (C-FARSIDE) will facilitate deep transdisciplinary collaborations...

    Checked 2 days ago against the source

  16. Federal

    Plant Genome Research Program

    U.S. National Science Foundation · Open

    Deadline
    No deadline listed: see the official notice
    Award
    Amount not specified
    • Available in Tennessee (nationwide program)
    • No match required
    • Past Tennessee awards on file: 74

    The Plant Genome Research Program (PGRP) supports genome-scale research that addresses challenging questions of biological, societal and economic importance. PGRP encourages the development of innovative tools, technologies, and resources that empower a...

    Checked today against the source

  17. Federal

    Accelerating Discovery through Partnered Research with All of Us to Analyze Participant Biospecimens (X01 Clinical Trial Not Allowed)

    National Institutes of Health · Department of Health and Human Services · Open

    Deadline
    Due Mar 1, 2027 · 144 days left
    Award
    Amount not specified
    • Available in Tennessee (nationwide program)
    • No match required
    • Past Tennessee awards on file: 2

    The purpose of this Program Announcement with Special Receipt, Referral, and/or Review Considerations (PAR) is to solicit applications to access stored blood plasma, blood serum, and extracted DNA from the All of Us Research Program supported Biobank to...

    Checked today against the source

  18. Federal

    National Science Foundation Translation to Practice (NSF TTP)

    U.S. National Science Foundation · Open

    Deadline
    Due Nov 17, 2026 · 40 days left
    Award
    $600K – $2M
    • Available in Tennessee (nationwide program)
    • No match required
    • Past Tennessee awards on file: 628

    The U.S. NSF Directorate for Technology, Innovation and Partnerships (NSF TIP) partners across sectors to advance three primary focus areas – accelerating technology translation and development, fostering regional innovation and economic growth, and...

    Checked today against the source

  19. Federal

    Maximizing Investigators' Research Award (MIRA) (R35 - Clinical Trial Optional)

    National Institutes of Health · Department of Health and Human Services · Open

    Deadline
    Due May 26, 2028 · 596 days left
    Award
    Amount not specified
    • Available in Tennessee (nationwide program)
    • No match required
    • Past Tennessee awards on file: 115

    The Maximizing Investigators' Research Award (MIRA) provides support for individual investigators for research within the scientific mission of NIGMS via a single grant to achieve the following:Increase the stability of funding for NIGMS-supported...

    Checked today against the source

  20. Federal

    Exploratory/Developmental Grants Related to the World Trade Center Health Program (R21)

    Centers for Disease Control and Prevention - ERA · Department of Health and Human Services · Open

    Deadline
    Due Dec 8, 2026 · 61 days left
    Award
    Up to $365K
    • Available in Tennessee (nationwide program)
    • No match required
    • Past Tennessee awards on file: 4

    The World Trade Center (WTC) Health Program supports exploratory and developmental research projects (R21) that address issues related to diagnostic or treatment uncertainty among individuals receiving monitoring and/or treatment under Subtitle C of the...

    Checked today against the source

Get these deadlines in your calendar

Add every upcoming deadline from this search to Outlook, Google or Apple Calendar. You'll get reminders 30 and 7 days before each one. A subscribed calendar updates by itself when grants are added or dates change. No account or email needed.

Subscribe (updates automatically) Download once (.ics)

Google Calendar: right-click “Download once” and copy the link address. In Google Calendar choose “Other calendars → From URL”, then paste it. It will keep updating.

Follow new grants for this search

Paste this feed link into a feed reader (Feedly, Inoreader), Outlook's RSS folder, or a Slack or Teams RSS app. New grants that match this search show up there as GrantMe adds them. No account or email needed.

RSS feed for this search This week's new grants

Foundations that have funded “Breakthrough”

Private foundations rarely post open calls. These gave grants like this in their latest IRS filing. 10 invitation-only foundations hidden.

See all matching foundations →