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U.S. Department of Health and Human Services, National Institutes of Health

Discovery and Applied Research for Technological Innovations to Improve Human Health

Federal program · program number 93.286 (the federal Assistance Listing number)

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51 grants
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7 grants
Type of help
Project grant
Typical award
FY 23 range $2,500 - $9,231,842; average $420,473 FY 24 range $5,405 - $3,565,780; average $425,722 FY 25 range $10,000 - $2,198,313; average $395,948

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What it pays for

To support hypothesis-, design-, technology-, or device-driven research related to the discovery, design, development, validation, and application of technologies for biomedical imaging and bioengineering. The program includes biomaterials (biomimetics, bioprocessing, organogenesis, rehabilitation, tissue engineering, implant science, material science, interface science, physics and stress engineering, technology assessment of materials/devices), biosensors/biotransducers (technology development, technology assessment, development of algorithms, telemetry), nanotechnology (nanoscience, biomimetics, drug delivery systems, drug bioavailability, microarray/combinatorial technology, genetic engineering, computer science, technology assessment), bioinformatics (computer science, information science, mathematics, biomechanics, computational modeling and simulation, remote diagnosis and therapy), imaging device development, biomedical imaging technology development, image exploitation, contrast agents, informatics and computer sciences related to imaging, molecular and cellular imaging, bioelectrics/biomagnetics, organ and whole body imaging, screening for diseases and disorders, and imaging technology assessment and surgery (technique development and technology development).

Who can apply

Any corporation, public or private institution or agency, or other legal entity, either nonprofit or for-profit, may apply for a research grant. An applicant for an individual NRSA must be a citizen of the United States or lawfully admitted for permanent residence. Those on temporary or student visas are not eligible. An eligible institution for an institutional NRSA must be capable of providing predoctoral and/or postdoctoral research training opportunities for engineers, bioengineers or other. SBIR grants can be awarded only to domestic small businesses (entities that are independently owned and operated for profit; are not dominant in the field in which research is being proposed; and have no more than 500 employees). Primary employment (more than one-half time) of the principal investigator must be with the small business at the time of award and during the conduct of the proposed project. In both Phase I and Phase II, the research must be performed in the United States or its possessions. To be eligible for funding, a grant application must be reviewed for scientific merit and program relevance by a scientific review group and a national advisory council. STTR grants can be awarded only to domestic small business concerns (entities that are independently owned and operated for profit, are not dominant in the field in which research is proposed and have no more than 500...

How applications are judged

The major elements in evaluating proposals include assessments of: (1) Significance: Does this study address an important problem? If the aims of the application are achieved, how will scientific knowledge be advanced? What will be the effect of these studies on the concepts or methods that drive this field? (2) Approach: Are the conceptual framework, design, methods, and analyses adequately developed, well-integrated, and appropriate to the aims of the project? Does the applicant acknowledge potential problem areas and consider alternative tactics? (3) Innovation: Does the project employ novel concepts, approaches or method? Are the aims original and innovative? Does the project challenge existing paradigms or develop new methodologies or technologies? (4) Investigator: Is the investigator appropriately trained and well suited to carry out this work? Is the work proposed appropriate to the experience level of the principal investigator and other researchers (if any)? (5) Environment: Does the scientific environment in which the work will be done contribute to the probability of success? Do the proposed experiments take advantage of unique features of the scientific environment or employ useful collaborative arrangements? Is there evidence of institutional support? (6) the appropriateness of the proposed budget and duration in relation to the proposed research; (7) the relevance and importance to announced program objectives; (8) the adequacy of plans to include both...

Match

None required (federal program listing).

Who in Tennessee has won this program

26 awards to Tennessee groups since 2003 · 0 in Gibson County. Largest shown:

Past winnerWhereAmountFiscal year
Vanderbilt University Medical CenterNashville, Davidson County$5.4M2003
Vanderbilt UniversityNashville, Davidson County$5.1M2015
Vanderbilt UniversityNashville$4.5M spent that year2025
Vanderbilt UniversityNashville, Davidson County$4M2014
Vanderbilt University Medical CenterNashville, Davidson County$3.3M spent that year2025
Vanderbilt UniversityNashville, Davidson County$3.2M2012
State of TennesseeNashville$3.1M spent that year2025
Vanderbilt University Medical CenterNashville, Davidson County$2.6M2014
Vanderbilt UniversityNashville, Davidson County$2.6M2022
Vanderbilt UniversityNashville, Davidson County$2.5M2019
University of TennesseeKnoxville, Knox County$2.4M2022
Vanderbilt UniversityNashville, Davidson County$2.4M2022

Source: USAspending.gov, Federal Audit Clearinghouse.

Tennessee groups that got this money through a state agency or another organization

This federal money also reaches local groups as pass-through grants. 46 pass-through grants on file · 0 in Gibson County. Largest shown:

Past winnerWhereThroughAmountFiscal year
Vanderbilt University Medical CenterNashville, Davidson CountyVanderbilt University$946K spent that year2025
Vanderbilt University Medical CenterNashville, Davidson CountyUniversity of Massachusetts Lowell$447K2025
Vanderbilt UniversityNashville, Davidson CountyThe Univeristy of Texas M.d. Anderson Cancer Center$400K2025
Vanderbilt University Medical CenterNashville, Davidson CountyPurdue University$369K2024
Vanderbilt University Medical CenterNashville, Davidson CountyVanderbilt University$361K2024
Vanderbilt University Medical CenterNashville, Davidson CountyVanderbilt University$354K2024
Vanderbilt University Medical CenterNashville, Davidson CountyVanderbilt University$347K2025
Vanderbilt UniversityNashvilleYaya Scientific, LLC$342K spent that year2025
Vanderbilt University Medical CenterNashville, Davidson CountyVanderbilt University$335K2023
Xtallized Intelligence IncChapmansboroThe General Hospital Corporation$306K2024
Vanderbilt University Medical CenterNashville, Davidson CountyPurdue University$292K2023
Vanderbilt University Medical CenterNashville, Davidson CountyVanderbilt University$237K2025

Source: USAspending.gov pass-through reports (the first recipient reports each one of $30,000 or more).

Official program listing (SAM.gov) Program website