U.S. Department of Health and Human Services, National Institutes of Health
Drug Use and Addiction Research Programs
Key facts
Open now
- Addressing Methodological Challenges with Clinical Trials of Rapid-Acting Psychotropic Interventional Drugs (RAPIDs) (R01 Clinical Trial Required) · Due Oct 11, 2026 · 4 days left
- NIDA Mentored Clinical Scientist Development Program Award in Substance Use and Substance Use Disorder Research (K12 Clinical Trial Optional) · Due Nov 13, 2026 · 37 days left
- Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional) · Due Nov 16, 2026 · 40 days left
- Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional) · Due Nov 18, 2026 · 42 days left
- Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional) · Due Nov 18, 2026 · 42 days left
- Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional) · Due Nov 24, 2026 · 48 days left
- Emerging Global Leader Award (K43 Independent Clinical Trial Required) · Due Dec 3, 2026 · 57 days left
- Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed) · Due Dec 3, 2026 · 57 days left
- NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed) · Due Dec 4, 2026 · 58 days left
- Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required) · Due Jan 7, 2027 · 92 days left
- Intervention Research to Improve Native American Health (R01 Clinical Trial Optional) · Due Jan 7, 2027 · 92 days left
- Intervention Research to Improve Native American Health (R34 Clinical Trial Optional) · Due Jan 7, 2027 · 92 days left
- HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required) · Due Jan 26, 2027 · 111 days left
- HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR) - Building Engagement, Assistance, Capacity, Outreach, and Networks (BEACON) Center (U2C Clinical Trial Not Allowed) · Due Jan 26, 2027 · 111 days left
- Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed) · Due Jan 27, 2027 · 112 days left
- BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed) · Due Jan 28, 2027 · 113 days left
- BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed) · Due Feb 8, 2027 · 124 days left
- BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Clinical Trial Not Allowed) · Due Feb 11, 2027 · 127 days left
- NIDA Animal Genomics Program (U01 Clinical Trial Not Allowed) · Due Feb 11, 2027 · 127 days left
- Discovery of in vivo Chemical Probes for the Nervous System (R01 Clinical Trial Not Allowed) · Due Mar 5, 2027 · 149 days left
- High Priority HIV and Substance Use Research (RM1 Clinical Trial Optional) · Due Mar 5, 2027 · 149 days left
- High Priority HIV and Substance Use Research (R01 Clinical Trial Optional) · Due Mar 6, 2027 · 150 days left
- Development and Testing of Novel Interventions to Improve HIV Prevention, Treatment, and Program Implementation for People Who Use Substances (R34 Clinical Trial Required) · Due Mar 16, 2027 · 160 days left
- NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) · Due Apr 5, 2027 · 180 days left
- NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional) · Due Apr 5, 2027 · 180 days left
- Short Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 Clinical Trials Not Allowed) · Due Apr 9, 2027 · 184 days left
- Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional) · Due Apr 18, 2027 · 193 days left
- Pilot Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R34 Clinical Trial Optional) · Due May 7, 2027 · 212 days left
- Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required) · Due May 7, 2027 · 212 days left
- Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Not Allowed) · Due May 7, 2027 · 212 days left
- Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed) · Due May 7, 2027 · 212 days left
- NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed) · Due May 7, 2027 · 212 days left
- Independent Scientist Award (Parent K02 - Independent Clinical Trial Not Allowed) · Due May 7, 2027 · 212 days left
- Independent Scientist Award (Parent K02 - Independent Clinical Trial Required) · Due May 7, 2027 · 212 days left
- Screening, Brief Intervention and Referral to Treatment or Prevention (SBIRT/P) for alcohol, tobacco, and other drugs (ATOD) use and misuse in adult populations that experience health disparities (R01, Clinical Trial Required) · Due May 7, 2027 · 212 days left
- NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required) · Due May 7, 2027 · 212 days left
- Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Not Allowed) · Due May 7, 2027 · 212 days left
- Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Required) · Due May 7, 2027 · 212 days left
- Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed) · Due May 7, 2027 · 212 days left
- Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Required) · Due May 7, 2027 · 212 days left
- Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Required) · Due May 8, 2027 · 213 days left
- Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required) · Due May 8, 2027 · 213 days left
- Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed) · Due May 8, 2027 · 213 days left
- BRAIN Initiative: Reagent Resources for Brain Cell Type-Specific Access to Broaden Distribution of Enabling Technologies for Neuroscience (U24 Clinical Trial Not Allowed) · Due Jun 15, 2027 · 251 days left
- Change of Recipient Organization (Type 7 Parent Clinical Trial Optional) · Due Jul 12, 2027 · 278 days left
- Successor-in-Interest (Type 6 Parent Clinical Trial Optional) · Due Jul 17, 2027 · 283 days left
- Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional) · Due Aug 11, 2027 · 308 days left
- Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional) · Due Aug 18, 2027 · 315 days left
- NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) · Due Sep 7, 2027 · 335 days left
- BRAIN Initiative Connectivity across Scales (BRAIN CONNECTS): Specialized Projects for Scalable Technologies (U01 Clinical Trial Not Allowed) · Due Oct 4, 2027 · 362 days left
- Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Required) · Due Oct 25, 2027 · 383 days left
- Mechanistic Evaluation of Therapeutic Targets derived from Treatable Traits to Improve CNS Outcomes in People with HIV (R21/R33 Clinical Trial Not Allowed) · Due Oct 28, 2027 · 386 days left
- BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain (R01 Clinical Trial Not Allowed) · Due Nov 8, 2027 · 397 days left
- Chemical Countermeasures Research Program (CCRP) Initiative: Basic Research on The Deleterious Effects of Acute Exposure to Ultra-Potent Synthetic (UPS) Opioids (R01 Clinical Trial Not Allowed) · Due Nov 18, 2027 · 407 days left
- Accelerating the Pace of Substance Use Research Using Existing Data (R21 Clinical Trial Not Allowed) · Due Dec 3, 2027 · 422 days left
- Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed) · Due Dec 3, 2027 · 422 days left
- Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed) · Due Jan 7, 2028 · 457 days left
- Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required) · Due Jan 7, 2028 · 457 days left
- NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed) · Due Jan 7, 2028 · 457 days left
- Dissemination and Implementation Research in Health (R21 Clinical Trial Optional) · Due Jan 7, 2028 · 457 days left
- NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required) · Due Jan 7, 2028 · 457 days left
- Dissemination and Implementation Research in Health (R01 Clinical Trial Optional) · Due Jan 7, 2028 · 457 days left
- Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) · Due Jan 7, 2028 · 457 days left
- Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed) · Due Jan 7, 2028 · 457 days left
- The Role of Work in Health Disparities in the U.S. (R01 Clinical Trials Optional) · Due Jan 7, 2028 · 457 days left
- NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) · Due Jan 7, 2028 · 457 days left
- NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed) · Due Jan 7, 2028 · 457 days left
- NIH Research Project Grant (Parent R01 Clinical Trial Required) · Due Jan 7, 2028 · 457 days left
- Blueprint MedTech Translator (UG3/UH3 - Clinical Trial Optional) · Due Jan 28, 2028 · 478 days left
- Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32) · Due May 4, 2028 · 575 days left
- Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) · Due May 7, 2028 · 578 days left
- Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32) · Due May 7, 2028 · 578 days left
- Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33) · Due May 7, 2028 · 578 days left
- Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) · Due May 7, 2028 · 578 days left
- Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) · Due May 7, 2028 · 578 days left
- Exploratory Clinical Neuroscience Research on Substance Use Disorders (R61/R33 Clinical Trial Optional) · Due Jun 16, 2028 · 618 days left
- BRAIN Initiative: Integrative Team-Research BRAIN Circuits Program - iBCP (RM1 Clinical Trial Not Allowed) · Due Jun 23, 2028 · 625 days left
- Development of Interventions to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional) · Due Aug 21, 2028 · 684 days left
- Support for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed) · Due Sep 7, 2028 · 701 days left
- Support for Research Excellence First Independent Research (SuRE-First) Award (R16 - Clinical Trial Not Allowed) · Due Sep 7, 2028 · 701 days left
- Avant Garde/Avenir Awards for Investigators Conducting High Risk/High Reward Research on HIV and Substance Use (or Substance Use Disorders) (DP1 Clinical Trial Optional) · Due Sep 25, 2028 · 719 days left
- Development of Candidate Medical Countermeasures (MCMs) and Technologies Against Radiological/Nuclear or Chemical Threats (U01 Clinical Trial Not Allowed) · Due Oct 9, 2028 · 733 days left
- CCRP Initiative: Promoting a Basic Understanding of Chemical Threats to Skin (R01 Clinical Trial Not Allowed) · Due Nov 5, 2028 · 760 days left
- Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional) · Due Nov 30, 2028 · 785 days left
- BRAIN Initiative: Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R01 Clinical Trial Not Allowed) · Due Feb 8, 2029 · 855 days left
- HEAL Initiative: Translating Addiction Epidemiology, Prevention, Treatment, and Recovery Research into Practice (R61/R33 - Clinical Trial Optional) · Due Feb 9, 2029 · 856 days left
- HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional) · Due Feb 20, 2029 · 867 days left
- Science Track Award for Research Transition (START) Program (R03, Clinical Trial Optional) · Due Mar 16, 2029 · 891 days left
- Predoctoral to Postdoctoral Transition Award (Parent F99/K00 - Clinical Trial Not Allowed) · Due Apr 8, 2029 · 914 days left
- NIH Brain Development Cohorts (NBDC) and Population Assessment of Tobacco and Health (PATH) Study Biospecimen Access (X01 Clinical Trial Not Allowed) · Due Apr 17, 2029 · 923 days left
- NIH Research Educational Program - Mentoring Activities & Networks (Parent R25/UE5 - Clinical Trial Not Allowed) · Due May 5, 2029 · 941 days left
- NIH Research Education Program - Research Experiences (Parent R25 - Clinical Trial Not Allowed) · Due May 5, 2029 · 941 days left
- NIH Research Education Program - Courses, Curriculum & Methods (Parent R25 - Clinical Trial Not Allowed) · Due May 25, 2029 · 961 days left
- NIH Science Education Partnership Award (SEPA) (R25 - Clinical Trial Not Allowed) · Due May 25, 2029 · 961 days left
- Implementation Science to Advance HIV Prevention, Treatment, and Care (R61/R33 Clinical Trial Optional) · Due Jun 20, 2029 · 987 days left
- Institutional Mentored Career Development Award (Parent K12) (Clinical Trials Not Allowed) · Due Jul 12, 2029 · 1009 days left
Opening soon
Announced, but you can't apply yet. Get ready now.
- Small Business Translator: MedTech and Digital Health Technologies · The funder's estimated date (Oct 20, 2025) has passed. Check the official notice Estimate, not confirmed by the funder
- NIH Research Program Projects (Parent P01 Clinical Trial Optional) · The funder's estimated date (Sep 25, 2026) has passed. Check the official notice Estimate, not confirmed by the funder
- NIDA Core "Center of Transformative Science" Grant Program · The funder's estimated date (Sep 25, 2026) has passed. Check the official notice Estimate, not confirmed by the funder
- Pilot and Feasibility Studies in Preparation for Substance Use and HIV Prevention Intervention and Services Research Trials · The funder's estimated date (Oct 2, 2026) has passed. Check the official notice Estimate, not confirmed by the funder
- Neural Ensembles & Used Substances (NExUS) Collaboratory: Building a Multimodal Inventory of Cell Ensembles Encoding the Effects of Addictive Substances · Due about Oct 7, 2026 Estimate, not confirmed by the funder
- NIH Blueprint Initiative: Tools for Germline Gene Editing in the Nervous System · Due about Oct 12, 2026 Estimate, not confirmed by the funder
- Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional) · Opens Nov 5, 2026 · due about Jan 5, 2027 Estimate, not confirmed by the funder
- Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional) · Opens Nov 5, 2026 · due about Jan 5, 2027 Estimate, not confirmed by the funder
- NIDA Avenir Program: Fundamental Mechanistic Research in Addiction Science · Opens Feb 1, 2027 · due about May 26, 2027 Estimate, not confirmed by the funder
- Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Phase 2 · Opens Feb 1, 2027 · due about Jun 8, 2027 Estimate, not confirmed by the funder
- Intervention Research to Improve Native American Health · Opens Oct 22, 2026 · due about Oct 18, 2027 Estimate, not confirmed by the funder
What it pays for
To support basic, clinical, translational, and implementation research in the field of substance use. To develop new knowledge and approaches for the prevention, diagnosis, and treatment of drug use, misuse, and addiction, drug overdose, and related health outcome, including HIV/AIDS. To support research training and research scientist development. To support dissemination of research findings.
Small Business Innovation Research (SBIR) legislation is intended to expand and improve the SBIR programs to emphasize and increase private sector commercialization of technology developed through Federal SBIR research and development; increase small business participation in Federal research and development; and foster and encourage participation of socially and economically disadvantaged small business concerns and women-owned small business concerns in the SBIR program. The Small Business Technology Transfer (STTR) legistlation is intended to stimulate and foster scientific and technological innovation through cooperative research and development carried out between small business concerns and research institutions; foster technology transfer between small business concerns and research institutions; increase private sector commercialization of innovations derived from Federal research and development; and foster and encourage participation of socially and economically disadvantaged small business concerns and women-owned small business concerns in technological innovation.
Who can apply
In each year's official notice: Addressing Methodological Challenges with Clinical Trials of Rapid-Acting Psychotropic Interventional Drugs (RAPIDs) (R01 Clinical Trial Required)
How applications are judged
The following considerations will be used in determining projects to be funded: (1) Scientific and technical merit; (2) the feasibility of the research; (3) potential contribution to the national drug abuse problem; and (4) relevance to NIDA priorities. The following criteria will be used in considering the scientific and technical merit of SBIR/STTR Phase I grant applications: (1) The soundness and technical merit of the proposed approach; (2) the qualifications of the proposed principal investigator, supporting staff, and consultants; (3) the technological innovation of the proposed research; (4) the potential of the proposed research for commercial application; (5) the appropriateness of the budget requested; (6) the adequacy and suitability of the facilities and research environment; and (7) where applicable, the adequacy of assurances detailing the proposed means for (a) safeguarding human or animal subjects and/or (b) protecting against or minimizing any adverse effect on the environment. Phase II grant applications will be reviewed based upon the following criteria: (1) The degree to which the Phase I objectives were met and feasibility demonstrated; (2) the scientific and technical merit of the proposed approach for achieving the Phase II objectives; (3) the qualifications of the proposed principal investigator, supporting staff, and consultants; (4) the technology.
Match
None required (federal program listing).
Who in Tennessee has won this program
19 awards to Tennessee groups since 2016 · 0 in Tipton County. Largest shown:
| Past winner | Where | Amount | Fiscal year |
|---|---|---|---|
| Vanderbilt University Medical Center | Nashville, Davidson County | $4.5M | 2016 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $4.4M | 2023 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $4M | 2022 |
| University of Tennessee | Memphis, Shelby County | $3.9M | 2017 |
| Meharry Medical College | Nashville, Davidson County | $3.7M | 2022 |
| University of Tennessee | Knoxville, Knox County | $3.5M | 2019 |
| University of Tennessee | Memphis, Shelby County | $3.4M | 2021 |
| University of Tennessee | Memphis, Shelby County | $3.1M | 2019 |
| St Jude Children's Research Hospital Inc | Memphis, Shelby County | $3.1M | 2022 |
| University of Tennessee | Memphis, Shelby County | $3.1M | 2022 |
| University of Tennessee | Memphis, Shelby County | $3M | 2023 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $2.9M | 2019 |
Source: USAspending.gov.
Tennessee groups that got this money through a state agency or another organization
This federal money also reaches local groups as pass-through grants. 10 pass-through grants on file · 0 in Tipton County. Largest shown:
| Past winner | Where | Through | Amount | Fiscal year |
|---|---|---|---|---|
| Ut-Battelle LLC | Oak Ridge, Anderson County | Research Triangle Institute | $368K | 2023 |
| St Jude Children's Research Hospital Inc | Memphis, Shelby County | University of Kentucky Research Foundation, the | $361K | 2023 |
| Ut-Battelle LLC | Oak Ridge, Anderson County | Research Triangle Institute | $345K | 2023 |
| Ut-Battelle LLC | Oak Ridge, Anderson County | Research Triangle Institute | $345K | 2024 |
| Ut-Battelle LLC | Oak Ridge, Anderson County | Research Triangle Institute | $344K | 2024 |
| Ut-Battelle LLC | Oak Ridge | Research Triangle Institute | $319K | 2026 |
| Ut-Battelle LLC | Oak Ridge, Anderson County | Research Triangle Institute | $319K | 2024 |
| Ut-Battelle LLC | Oak Ridge | Research Triangle Institute | $319K | 2026 |
| Vanderbilt University | Nashville, Davidson County | Regents of the University of Minnesota | $245K | 2025 |
| St Jude Children's Research Hospital Inc | Memphis, Shelby County | University of Kentucky Research Foundation, the | $224K | 2023 |
Source: USAspending.gov pass-through reports (the first recipient reports each one of $30,000 or more).