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U.S. National Science Foundation

Unlocking Dataset Value for AI-Enabled Scientific Discovery (AI Datasets)

Open

Key facts

Deadline
Due Nov 4, 2026 · 27 days left
Award size
Not stated: see the official notice
Total available
$100M · about 50 awards
Match ?
Not required · Work out your budget and match
Who can apply
Set by the official notice: see Who can apply below
Where
Anywhere in the U.S., including Tennessee

Before you apply: federal grants require an active SAM.gov registration (Unique Entity ID) and a Grants.gov account. The deadline is in 27 days. If your registration isn't already active, it may not be ready in time, so check it today. Get-ready checklist

How this fits you

  • Available in Weakley County (nationwide program)
  • No match required
  • Past Tennessee awards on file: 316

Tell us who you are to see whether you're eligible.

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About this grant

This program will advance scientific community datasets to enable scientific discovery and innovation using artificial intelligence (AI) and other methods. Its goal is to increase the value that can be derived from existing scientific datasets by leveraging novel methods and artificial intelligence (AI). This will unlock new AI-driven insights. It can enable interdisciplinary research. It also enables investigations outside of the original motivation for data collection and analysis. The program seeks to 1) apply AI-based capabilities to feature extraction and metadata generation, and the integration of multiple datasets. 2) Develop robust data pipelines necessary for automated analysis of existing datasets and similar use-cases by AI tools and systems. 3) Augment and/or harmonize existing datasets to better enable use by AI data pipelines and automated analysis. Proposals should address dataset security and integrity. Governance and the process for scientific communities to contribute to the datasets should also be addressed. Proposals are encouraged to leverage existing resources. These may include NSF data platforms, the NSF Integrated Data Systems and Services program, the NSF-led National AI Research Resource, the Genesis Mission platform, or other national infrastructure. NSF is open to exploring partnerships with philanthropy, private industry, or the non-profit sector to support additional proposals or collaborative opportunities that will advance AI-driven scientific discovery through unlocking the value of high-impact scientific datasets. Expanding Participation in STEM, NSF Priorities, and Gold Standard Science: NSF prioritizes cutting-edge discovery science and engineering research, advancing technology and innovation, and creating opportunities for all Americans. NSF has established priorities set forth by Congress, the administration and the NSF director to promote NSF's mission. Proposers should review the list of NSF priorities and are encouraged to align their proposals with them, where appropriate. NSF also expects the highest standards of scientific rigor, integrity and adherence tenets of Gold Standard Science in proposals, as appropriate for the field of science and research modality.

Who can apply, from the official notice

*Who May Submit Proposals: Proposals may only be submitted by the following: -For-profit organizations: U.S.-based commercial organizations, including small businesses, with strong capabilities in scientific or engineering research or education and a passion for innovation. -Non-profit, non-academic organizations: Independent museums, observatories, research laboratories, professional societies and similar organizations located in the U.S. that are directly associated with educational or research activities. -Other Federal Agencies and Federally Funded Research and Development Centers (FFRDCs): Prospective proposers from other Federal Agencies and FFRDCs, including NSF sponsored FFRDCs, must follow the guidance in PAPPG Chapter I.E.2 regarding limitations on eligibility. -State and Local Governments -Institutions of Higher Education (IHEs): Two- and four-year IHEs (including community colleges) accredited in, and having a campus located in the US, acting on behalf of their faculty members. Special Instructions for International Branch Campuses of US IHEs: If the proposal includes funding to be provided to an international branch campus of a US institution of higher education (including through use of sub-awards and consultant arrangements), the proposer must explain the benefit(s) to the project of performance at the international branch campus, and justify why the project activities cannot be performed at the US campus. -Tribal Nations: An American Indian or Alaska Native tribe, band, nation, pueblo, village, or community that the Secretary of the Interior acknowledges as a federally recognized tribe pursuant to the Federally Recognized Indian Tribe List Act of 1994, 25 U.S.C. §§ 5130-5131.

Ask a partner for a letter

Your schedule, working back from the deadline

  1. Oct8
    Check that your SAM.gov registration is active (or start it now)
    Grants.gov: allow up to 10 business days for SAM registration, weeks or months if information isn't verified. It must be renewed every year. Grants.gov
  2. Oct14
    Ask partners for letters of support or commitment
    Suggested: partners need about three weeks to write and sign letters.
  3. Oct28
    Finish a complete draft for a final review
    Suggested: leave about a week for someone else to read the draft.
  4. Nov2
    Submit
    Grants.gov: submit at least 24–48 hours before the deadline: uploads fail, systems slow down, errors need fixing. Grants.gov blog
  5. Nov4
    Deadline
    From the funder.

Save this grant to put these dates in My grants and your private calendar.

Writing the need statement? Weakley County facts with citations.

Who in Tennessee has won this program

131 awards to Tennessee groups in 8 counties since 2016 · 0 in Weakley County. Largest shown:

Past Tennessee winners
Past winnerWhereAmountFiscal year
Vanderbilt UniversityNashville, Davidson County$15M2023
State of TennesseeNashville$12.2M spent that year2025
University of TennesseeKnoxville, Knox County$11.7M2023
State of TennesseeNashville$7.3M spent that year2025
State of TennesseeNashville$6.7M spent that year2025
University of TennesseeKnoxville, Knox County$5M2026
Vanderbilt UniversityNashville, Davidson County$5M2022
Vanderbilt UniversityNashville$4.5M spent that year2025
Vanderbilt UniversityNashville, Davidson County$4M2025
Vanderbilt UniversityNashville$3.7M spent that year2025
Vanderbilt UniversityNashville$3.5M spent that year2025
Vanderbilt UniversityNashville, Davidson County$3M2024

Source: USAspending.gov; Federal Audit Clearinghouse. Past awards show who this program funds. They don't guarantee future awards.

Tennessee groups that got this money through a state agency or another organization

This federal money also reaches local groups as pass-through grants. 185 pass-through grants on file · 0 in Weakley County. Largest shown:

Tennessee pass-through grant winners
Past winnerWhereThroughAmountFiscal year
University of TennesseeKnoxville, Knox CountyHudsonalpha Institute for Biotechnology$1.7M2026
Fisk UniversityNashville, Davidson CountyVanderbilt University$956K2024
State of TennesseeNashvilleThe Ohio State University$849K spent that year2025
Meharry Medical CollegeNashville, Davidson CountyVirginia Polytechnic Institute & State University$767K2025
Aglaunch InitiativeMemphis, Shelby CountyNorth Dakota State University$703K2026
University of TennesseeKnoxville, Knox CountyUniversity of Texas at San Antonio, the$490K2024
University of TennesseeKnoxville, Knox CountyUniversity of California Irvine$423K2025
Vanderbilt UniversityNashville, Davidson CountyTexas a & M University$388K2023
University of TennesseeKnoxville, Knox CountyThe University of Texas at San Antonio$386K2024
University of TennesseeMemphis, Shelby CountyColorado State University$386K2023
University of TennesseeKnoxville, Knox CountyBoard of Regents of the Nevada System of Higher Ed$370K2026
University of TennesseeKnoxville, Knox CountyUniversity of California Irvine$366K2026

Source: USAspending.gov pass-through reports (the first recipient reports each one of $30,000 or more).

About the federal program

Engineering, also called “(ENG)”
Program number 47.041 (the federal Assistance Listing number) · National Science Foundation · Project grant

Match

None required (federal program listing).

This program on SAM.gov

About the federal program

Mathematical and Physical Sciences, also called “(MPS)”
Program number 47.049 (the federal Assistance Listing number) · National Science Foundation · Project grant

Match

None required (federal program listing).

This program on SAM.gov

About the federal program

Geosciences, also called “(GEO)”
Program number 47.050 (the federal Assistance Listing number) · National Science Foundation · Project grant

Match

None required (federal program listing).

This program on SAM.gov

About the federal program

Biological Sciences, also called “(BIO)”
Program number 47.074 (the federal Assistance Listing number) · National Science Foundation · Project grant

Match

None required (federal program listing).

This program on SAM.gov

About the federal program

Technology, Innovation, and Partnerships, also called “NSF Directorate for Technology, Innovation, and Partnerships (TIP)”
Program number 47.084 (the federal Assistance Listing number) · National Science Foundation · Grant

Match

None required (federal program listing).

This program on SAM.gov

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