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U.S. National Science Foundation

Unlocking Dataset Value for AI-Enabled Scientific Discovery (AI Datasets)

Open · Opportunity 26-512 · Assistance Listing 47.074, 47.050, 47.041, 47.084, 47.049

Key facts

Deadline
Due Nov 4, 2026 · 28 days left
Award size
Not specified — see notice
Total available
$100M · about 50 awards
Cost share / match ?
Not required · Work out your budget and match
Who can apply
Other (see eligibility)
Where
Anywhere in the U.S., including Tennessee

Before you apply: federal grants require an active SAM.gov registration (Unique Entity ID) and a Grants.gov account. The deadline is in 28 days. If your registration isn't already active, it may not be ready in time, so check it today. Grant-ready checklist

How this fits you

  • Available in Tennessee (nationwide program)
  • No cost share required
  • Past Tennessee awards on file: 202

Tell us who you are to see whether you're eligible.

More from U.S. National Science Foundation

Read the official notice View on Grants.gov Add deadline to my calendar Sign in to save

About this grant

This program will advance scientific community datasets to enable scientific discovery and innovation using artificial intelligence (AI) and other methods. Its goal is to increase the value that can be derived from existing scientific datasets by leveraging novel methods and artificial intelligence (AI). This will unlock new AI-driven insights. It can enable interdisciplinary research. It also enables investigations outside of the original motivation for data collection and analysis. The program seeks to 1) apply AI-based capabilities to feature extraction and metadata generation, and the integration of multiple datasets. 2) Develop robust data pipelines necessary for automated analysis of existing datasets and similar use-cases by AI tools and systems. 3) Augment and/or harmonize existing datasets to better enable use by AI data pipelines and automated analysis. Proposals should address dataset security and integrity. Governance and the process for scientific communities to contribute to the datasets should also be addressed. Proposals are encouraged to leverage existing resources. These may include NSF data platforms, the NSF Integrated Data Systems and Services program, the NSF-led National AI Research Resource, the Genesis Mission platform, or other national infrastructure. NSF is open to exploring partnerships with philanthropy, private industry, or the non-profit sector to support additional proposals or collaborative opportunities that will advance AI-driven scientific discovery through unlocking the value of high-impact scientific datasets. Expanding Participation in STEM, NSF Priorities, and Gold Standard Science: NSF prioritizes cutting-edge discovery science and engineering research, advancing technology and innovation, and creating opportunities for all Americans. NSF has established priorities set forth by Congress, the administration and the NSF director to promote NSF's mission. Proposers should review the list of NSF priorities and are encouraged to align their proposals with them, where appropriate. NSF also expects the highest standards of scientific rigor, integrity and adherence tenets of Gold Standard Science in proposals, as appropriate for the field of science and research modality.

Eligibility (from the notice)

*Who May Submit Proposals: Proposals may only be submitted by the following: -For-profit organizations: U.S.-based commercial organizations, including small businesses, with strong capabilities in scientific or engineering research or education and a passion for innovation. -Non-profit, non-academic organizations: Independent museums, observatories, research laboratories, professional societies and similar organizations located in the U.S. that are directly associated with educational or research activities. -Other Federal Agencies and Federally Funded Research and Development Centers (FFRDCs): Prospective proposers from other Federal Agencies and FFRDCs, including NSF sponsored FFRDCs, must follow the guidance in PAPPG Chapter I.E.2 regarding limitations on eligibility. -State and Local Governments -Institutions of Higher Education (IHEs): Two- and four-year IHEs (including community colleges) accredited in, and having a campus located in the US, acting on behalf of their faculty members. Special Instructions for International Branch Campuses of US IHEs: If the proposal includes funding to be provided to an international branch campus of a US institution of higher education (including through use of sub-awards and consultant arrangements), the proposer must explain the benefit(s) to the project of performance at the international branch campus, and justify why the project activities cannot be performed at the US campus. -Tribal Nations: An American Indian or Alaska Native tribe, band, nation, pueblo, village, or community that the Secretary of the Interior acknowledges as a federally recognized tribe pursuant to the Federally Recognized Indian Tribe List Act of 1994, 25 U.S.C. §§ 5130-5131.

Should we apply? (2-minute check) Ask a partner for a letter

Your schedule, working back from the deadline

  1. Oct7
    Check that your SAM.gov registration is active (or start it now)
    Grants.gov: allow up to 10 business days for SAM registration, weeks or months if information isn't verified. It must be renewed every year. Grants.gov
  2. Oct14
    Ask partners for letters of support or commitment
    Suggested: partners need time to write and sign letters.
  3. Oct28
    Finish a complete draft for a final review
    University grant offices require final versions about 5 business days before the sponsor deadline. Emory Office of Sponsored Programs
  4. Nov2
    Submit
    Grants.gov: submit at least 24–48 hours before the deadline: uploads fail, systems slow down, errors need fixing. Grants.gov blog
  5. Nov4
    Deadline
    From the funder.

Save this grant to put these dates in your tracker and private calendar.

Who in Tennessee has won this program

107 awards to Tennessee recipients in 8 counties since 2016. Largest shown:

Past Tennessee recipients
RecipientWhereAmountFY
Vanderbilt UniversityNashville, Davidson County$15M2023
University Of TennesseeKnoxville, Knox County$11.7M2023
University Of TennesseeKnoxville, Knox County$5M2026
Vanderbilt UniversityNashville, Davidson County$5M2022
Vanderbilt UniversityNashville, Davidson County$4M2025
Vanderbilt UniversityNashville, Davidson County$3M2024
Vanderbilt UniversityNashville, Davidson County$3M2024
University Of TennesseeKnoxville, Knox County$2.5M2018
University Of TennesseeKnoxville, Knox County$2.4M2021
University Of TennesseeKnoxville, Knox County$2.3M2022
Vanderbilt UniversityNashville, Davidson County$2M2023
University Of TennesseeKnoxville, Knox County$1.7M2024

Source: USAspending.gov. Past awards show who this program funds; they don't guarantee future awards.

Tennessee groups that got this money through a state agency or another grantee

This federal money also reaches local groups as subawards. 95 subawards on file. Largest shown:

Tennessee subaward recipients
RecipientWhereThroughAmountFY
University Of TennesseeKnoxville, Knox CountyHudsonalpha Institute for Biotechnology$1.7M2026
Fisk UniversityNashville, Davidson CountyVanderbilt University$956K2024
Meharry Medical CollegeNashville, Davidson CountyVirginia Polytechnic Institute & State University$767K2025
Aglaunch InitiativeMemphis, Shelby CountyNorth Dakota State University$703K2026
University Of TennesseeKnoxville, Knox CountyUniversity of Texas At San Antonio, the$490K2024
University Of TennesseeKnoxville, Knox CountyUniversity of California Irvine$423K2025
Vanderbilt UniversityNashville, Davidson CountyTexas A & M University$388K2023
University Of TennesseeKnoxville, Knox CountyThe University of Texas At San Antonio$386K2024
University Of TennesseeMemphis, Shelby CountyColorado State University$386K2023
University Of TennesseeKnoxville, Knox CountyBoard of Regents of the Nevada System of Higher Ed$370K2026
University Of TennesseeKnoxville, Knox CountyUniversity of California Irvine$366K2026
University Of TennesseeKnoxville, Knox CountyRegents of the University of Michigan$348K2024

Source: USAspending.gov subaward reports (prime recipients report subawards of $30,000 or more).

About the program (47.041)

Engineering — (ENG)

How applications are judged

Not Applicable.

Matching requirements

This program has no statutory formula. Matching requirements are not applicable to this assistance listing. MOE requirements are not applicable to this assistance listing.

Examples of funded projects

Not Applicable.

Program listing on SAM.gov

About the program (47.049)

Mathematical and Physical Sciences — (MPS)

How applications are judged

Not Applicable.

Matching requirements

This program has no statutory formula. Matching requirements are not applicable to this assistance listing. MOE requirements are not applicable to this assistance listing.

Examples of funded projects

Not Applicable.

Program listing on SAM.gov

About the program (47.050)

Geosciences — (GEO)

How applications are judged

Not Applicable.

Matching requirements

This program has no statutory formula. Matching requirements are not applicable to this assistance listing. MOE requirements are not applicable to this assistance listing.

Examples of funded projects

Not Applicable.

Program listing on SAM.gov

About the program (47.074)

Biological Sciences — (BIO)

How applications are judged

Not Applicable.

Matching requirements

This program has no statutory formula. Matching requirements are not applicable to this assistance listing. MOE requirements are not applicable to this assistance listing.

Examples of funded projects

Not Applicable.

Program listing on SAM.gov

About the program (47.084)

Technology, Innovation, and Partnerships — NSF Directorate for Technology, Innovation, and Partnerships (TIP)

How applications are judged

Not Applicable.

Matching requirements

This program has no statutory formula. Matching requirements are not applicable to this assistance listing. MOE requirements are not applicable to this assistance listing.

Examples of funded projects

Not Applicable.

Program listing on SAM.gov

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