National Institutes of Health · Department of Health and Human Services
Transformative Technologies for Experimental and Computational RNome Characterization and Functional Analysis
Key facts
- Deadline
- Expected around Feb 15, 2027 (not yet confirmed)
- Award size
- Up to $500K
- Total available
- $8M · about 10 awards
- Cost share / match ?
- Not required · Work out your budget and match
- Who can apply
- Special district (utility, fire, etc.), County government, Larger business, Nonprofit without 501(c)(3), Tribal government, Nonprofit with 501(c)(3), City or town government, Public college or university, Tribal organization, Other (see eligibility), State government, School district, Small business, Private college or university
- Where
- Anywhere in the U.S., including Tennessee
Before you apply: federal grants require an active SAM.gov registration (Unique Entity ID) and a Grants.gov account. Registration is free but can take weeks, so start now, not when the deadline is close. Grant-ready checklist
How this fits you
- Available in Tennessee (nationwide program)
- No cost share required
- Tennessee recipients since 2023: 23
Tell us who you are to see whether you're eligible.
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Official notice: https://simpler.grants.gov/opportunity/d74df651-ab55-4651-9c55-fc67b40d917c · Printed from grantme.click/grants/f5272e48-bef9-42df-8155-e754189ae712
Read the official notice View on Grants.gov Add dates to my calendar Sign in to save
About this grant
The NIH Common Fund, in partnership with other NIH Institutes and Centers, plans to issue Notices of Funding Opportunity (NOFOs) for the RNomics program, which seeks to develop tools for studying the full set of RNA molecules (the RNome) in cells and tissues. The program will support technologies and resources that enable integrated analysis of RNA sequences, modifications, structures, locations, interactions, and functions to advance understanding of health and disease. RNomics includes four initiatives: technology enhancement centers, transformative technologies, molecular standards, and a coordinating center. Applications are not being solicited at this time. This notice is being provided to give potential applicants time to develop meaningful collaborations and strong projects.
This NOFO will support the transformative technologies initiative. These phased projects will develop new experimental and computational RNA technologies that address major limitations of current methods. Projects will focus on early-stage, high-risk ideas not yet demonstrated at scale or in biologically relevant systems. Priority areas include tools to sequence RNA, detect modifications, study RNA function, and analyze RNA across molecules, cells, and tissues. Projects that successfully complete Phase 1 milestones will be evaluated for transition to Phase 2. Phase 2 projects are expected to deliver validated tools for community use.
Eligibility (from the notice)
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Who in Tennessee has won this program
23 awards to Tennessee recipients in 2 counties since federal FY2023. Largest shown:
| Recipient | Where | Amount | FY |
|---|---|---|---|
| Vanderbilt University Medical Center | Nashville, Davidson County | $143.7M | 2016 |
| Meharry Medical College | Nashville, Davidson County | $45.7M | |
| Vanderbilt University Medical Center | Nashville, Davidson County | $32.8M | 2023 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $27.5M | 1997 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $22M | 2016 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $19.6M | 2011 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $12.6M | 2016 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $9.3M | 2021 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $8.5M | 2022 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $8M | 2025 |
| University Of Memphis | Memphis, Shelby County | $7.7M | 2020 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $7.4M | 2002 |
Source: USAspending.gov. Past awards show who this program funds; they don't guarantee future awards.
About the program (93.310)
Trans-NIH Research Support — NIH-wide Research Support
How applications are judged
Funding decisions are based on scientific merit (42 CFR 52h) and program relevance. Scientific merit review encompasses: the peer review criteria detailed in the specific funding announcement, as well as the significance, approach, and innovation of the proposed research; the competency of the principal investigator; the adequacy of the resources and environment; the proposed budget and requested period of support; and, where applicable, the adequacy of the measures for protecting against adverse effects upon humans, animals, or the environment.
Matching requirements
This program has no statutory formula.
Matching requirements are not applicable to this assistance listing.
MOE requirements are not applicable to this assistance listing.
Examples of funded projects
Not Applicable.