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National Institutes of Health · Department of Health and Human Services

Molecular Imaging of Inflammation in Cancer (R01 Clinical Trial Not Allowed)

Open

Key facts

Deadline
Due Jan 7, 2028 · 457 days left
Award size
Up to $500K
Total available
$500K
Match ?
Not required · Work out your budget and match
Who can apply
City or town government, Nonprofit without 501(c)(3), County government, State government, Private college or university, Larger business, Tribal organization, Special district (utility, fire, etc.), Tribal government, Nonprofit with 501(c)(3), School district, Small business, Public college or university, and others named in the official notice
Where
Anywhere in the U.S., including Tennessee

Before you apply: federal grants require an active SAM.gov registration (Unique Entity ID) and a Grants.gov account. Registration is free but can take weeks, so start now, not when the deadline is close. Get-ready checklist

How this fits you

  • Available in Rhea County (nationwide program)
  • No match required
  • Past Tennessee awards on file: 281

Tell us who you are to see whether you're eligible.

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More from National Institutes of Health

About this grant

The purpose of this Notice of Funding Opportunity (NOFO) is to invite research grant applications (R01) for the development and use of current and emerging molecular imaging methods to gain fundamental insights into cancer inflammation in vivo. The motivation for this initiative is that much of current imaging research into the role of inflammation in cancer is largely based on in vitro and ex vivo methods with limited utilization of imaging approaches that could lead to significant new insights relevant to dynamic cancer and inflammation interactions. Utilization of molecular imaging probes in pre-clinical and clinical investigations for precise temporal resolution at the molecular and cellular level are valuable approaches for identification and characterization of in vivo inflammatory cellular physiology in cancers and of molecular changes in response to treatment. This FOA encourages applications that focus on developing integrated imaging approaches to interrogate the role of inflammation in cancer through strong cross-field collaboration between cancer basic science researchers and imaging scientists. These collaborations are expected to advance science and understanding of cancer inflammation interactions.

Who can apply, from the official notice

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

Ask a partner for a letter

Your schedule, working back from the deadline

  1. Oct7
    Check that your SAM.gov registration is active (or start it now)
    Grants.gov: allow up to 10 business days for SAM registration, weeks or months if information isn't verified. It must be renewed every year. Grants.gov
  2. Dec17
    Ask partners for letters of support or commitment
    Suggested: partners need about three weeks to write and sign letters.
  3. Dec31
    Finish a complete draft for a final review
    Suggested: leave about a week for someone else to read the draft.
  4. Jan5
    Submit
    Grants.gov: submit at least 24–48 hours before the deadline: uploads fail, systems slow down, errors need fixing. Grants.gov blog
  5. Jan7
    Deadline
    From the funder.

Save this grant to put these dates in My grants and your private calendar.

Writing the need statement? Rhea County facts with citations.

Who in Tennessee has won this program

79 awards to Tennessee groups in 2 counties since 1993 · 0 in Rhea County. Largest shown:

Past Tennessee winners
Past winnerWhereAmountFiscal year
St Jude Children's Research Hospital IncMemphis, Shelby County$81.5M1993
St Jude Children's Research Hospital IncMemphis, Shelby County$41.4M1999
St Jude Children's Research Hospital IncMemphis, Shelby County$31.4M2003
Vanderbilt University Medical CenterNashville, Davidson County$25.8M2009
St. Jude Children's Research Hospital, Inc.Memphis, Shelby County$14.7M spent that year2025
Vanderbilt University Medical CenterNashville, Davidson County$12.8M2010
Vanderbilt University Medical CenterNashville, Davidson County$12.6M2014
St Jude Children's Research Hospital IncMemphis, Shelby County$11.4M2017
Vanderbilt UniversityNashville, Davidson County$10.8M2020
Vanderbilt University Medical CenterNashville, Davidson County$9.4M2017
St Jude Children's Research Hospital IncMemphis, Shelby County$9.2M2018
Vanderbilt University Medical CenterNashville, Davidson County$9.2M spent that year2025

Source: USAspending.gov, Federal Audit Clearinghouse. Past awards show who this program funds. They don't guarantee future awards.

Tennessee groups that got this money through a state agency or another organization

This federal money also reaches local groups as pass-through grants. 202 pass-through grants on file · 0 in Rhea County. Largest shown:

Tennessee pass-through grant winners
Past winnerWhereThroughAmountFiscal year
St Jude Children's Research Hospital IncMemphis, Shelby CountyUniversity of Southern California$2.8M2023
Vanderbilt UniversityNashville, Davidson CountyVanderbilt University Medical Center$2.5M2023
St Jude Children's Research Hospital IncMemphis, Shelby CountyThe Johns Hopkins University$1.4M2025
St Jude Children's Research Hospital IncMemphis, Shelby CountyBaylor College of Medicine$1.4M2025
St. Jude Children's Research Hospital, Inc.Memphis, Shelby CountyPublic Health Institute$1.1M spent that year2023
St Jude Children's Research Hospital IncMemphis, Shelby CountyWashington University, the$1M2024
Vanderbilt University Medical CenterNashville, Davidson CountyVanderbilt University$1M2026
Vanderbilt University Medical CenterNashville, Davidson CountyRegents of the University of Michigan$974K2023
St Jude Children's Research Hospital IncMemphis, Shelby CountySeattle Children's Hospital$962K2025
St Jude Children's Research Hospital IncMemphis, Shelby CountyIcahn School of Medicine at Mount Sinai$815K2024
St. Jude Children's Research Hospital, Inc.Memphis, Shelby CountyUniversity of Southern California$811K spent that year2025
St Jude Children's Research Hospital IncMemphis, Shelby CountyUniversity of Southern California$785K2023

Source: USAspending.gov pass-through reports (the first recipient reports each one of $30,000 or more).

About the federal program

Cancer Detection and Diagnosis Research
Program number 93.394 (the federal Assistance Listing number) · U.S. Department of Health and Human Services, National Institutes of Health · Cooperative agreement (a grant with close agency involvement), project grant

How applications are judged

The major elements in evaluating proposals include assessments of: (1) The scientific merit and general significance of the proposed study and its objectives; 2) the technical adequacy of the experimental design and approach; (3) the competency of the proposed investigator or group to successfully pursue the project; (4) the adequacy of the available and proposed facilities and resources; (5) the necessity of the budget components requested in relation to the proposed project; and (6) the relevance and importance to announced program objectives. The following criteria will be used in considering the scientific and technical merit of SBIR/STTR Phase I grant applications: (1) The soundness and technical merit of the proposed approach; (2) the qualifications of the proposed principal investigator, supporting staff, and consultants; (3) the technological innovation of the proposed research; (4) the potential of the proposed research for commercial application; (5) the appropriateness of the budget requested; (6) the adequacy and suitability of the facilities and research environment; and (7) where applicable, the adequacy of assurances detailing the proposed means for (a) safeguarding human or animal subjects, and/or (b) protecting against or minimizing any adverse effect on the environment. Phase II grant applications will be reviewed based upon the following criteria: (1) The degree to which the Phase I objectives were met and feasibility demonstrated; (2) the scientific...

Match

None required (federal program listing).

This program on SAM.gov

About the federal program

Cancer Treatment Research
Program number 93.395 (the federal Assistance Listing number) · U.S. Department of Health and Human Services, National Institutes of Health · Cooperative agreement (a grant with close agency involvement), project grant

How applications are judged

The major elements in evaluating applications include assessments of: (1) The scientific merit and general significance of the proposed study and its objectives; (2) the technical adequacy of the experimental design and approach; (3) the competency of the proposed investigator or group to successfully pursue the project; (4) the adequacy of the available and proposed facilities and resources; (5) the necessity of the budget components requested in relation to the proposed project; and (6) the relevance and importance to announced program objectives. The following criteria will be used in considering the scientific and technical merit of SBIR/STTR Phase I grant applications: (1) The soundness and technical merit of the proposed approach; (2) the qualifications of the proposed principal investigator, supporting staff, and consultants; (3) the technological innovation of the proposed research; (4) the potential of the proposed research for commercial application; (5) the appropriateness of the budget requested; (6) the adequacy and suitability of the facilities and research environment; and (7) where applicable, the adequacy of assurances detailing the proposed means for (a) safeguarding human or animal subjects, and/or (b) protecting against or minimizing any adverse effect on the environment. Phase II grant applications will be reviewed based upon the following criteria: (1) The degree to which the Phase I objectives were met and feasibility demonstrated; (2) the...

Match

None required (federal program listing).

This program on SAM.gov

About the federal program

Cancer Biology Research
Program number 93.396 (the federal Assistance Listing number) · U.S. Department of Health and Human Services, National Institutes of Health · Cooperative agreement (a grant with close agency involvement), project grant

How applications are judged

The major elements in evaluating applications include assessments of: (1) The scientific merit and general significance of the proposed study and its objectives; (2) the technical adequacy of the experimental design and approach; (3) the competency of the proposed investigator or group to successfully pursue the project; (4) the adequacy of the available and proposed facilities and resources; (5) the necessity of the budget components requested in relation to the proposed project; and (6) the relevance and importance to announced program objectives. The following will be considered in making funding decisions: 1) Scientific and technical merit of the proposed project as determined by scientific peer review; 2) Availability of funds; and 3) Relevance of the proposed project to program priorities.

Match

None required (federal program listing).

This program on SAM.gov

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