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National Institutes of Health · Department of Health and Human Services

Mood and Psychosis Symptoms during the Menopause Transition (R01 Clinical Trial Optional)

Open · Opportunity PAR-25-281 · Assistance Listing 93.242, 93.313

Key facts

Deadline
Due Jan 7, 2028 · 457 days left
Award size
Not specified — see notice
Cost share / match ?
Not required
Who can apply
Special district (utility, fire, etc.), Other (see eligibility), Nonprofit with 501(c)(3), Tribal organization, State government, School district, Public college or university, Private college or university, Tribal government, Small business, Larger business, County government, Nonprofit without 501(c)(3), City or town government
Where
Anywhere in the U.S., including Tennessee

Before you apply: federal grants require an active SAM.gov registration (Unique Entity ID) and a Grants.gov account. Registration is free but can take weeks, so start now, not when the deadline is close. Grant-ready checklist

How this fits you

  • Available in Tennessee (nationwide program)
  • No cost share required
  • Tennessee recipients since 2023: 22

Tell us who you are to see whether you're eligible.

More from National Institutes of Health

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About this grant

The purpose of this Notice of Funding Opportunity (NOFO) is to advance translational research to better understand the emergence and worsening of mood and psychotic disorders (e.g., perimenopausal depression (PMD), generalized anxiety disorder, bipolar disorder and schizophrenia) during the menopause transition (MT) in an effort to identity targets for future development of novel treatment interventions. This funding opportunity aims to advance novel and innovative translational research to better comprehend the underlying neurobiological and behavioral mechanisms of mood and psychosis disorders and related symptoms during MT. This funding opportunity also encourages interdisciplinary researchers to collaborate on studies of mood and psychosis during the MT. Aspects of mood and psychosis disorders that are of interest include: classic depressive symptoms in combination with menopause symptoms (e.g., hot flashes, night sweats, sleep disturbance) and psychological challenges, the role of reproductive steroids in the regulation of mood and behavior during the MT, diagnosis of mood and psychosis symptoms at menopausal stage, investigation of co-occurring psychiatric and menopause symptoms, appreciation of psychosocial factors common in midlife, and differential diagnoses. Review criteria will focus on the comprehensiveness of the neurobiology and mechanisms of action underlying mood and psychosis symptoms and hypothesis-driven work.

Eligibility (from the notice)

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Who in Tennessee has won this program

22 awards to Tennessee recipients in 2 counties since federal FY2023. Largest shown:

Past Tennessee recipients
RecipientWhereAmountFY
Vanderbilt UniversityNashville, Davidson County$8.7M2001
Vanderbilt UniversityNashville, Davidson County$8.7M2006
Vanderbilt UniversityNashville, Davidson County$8.1M2005
Vanderbilt University Medical CenterNashville, Davidson County$7.4M2020
Vanderbilt UniversityNashville, Davidson County$6.8M2004
Vanderbilt University Medical CenterNashville, Davidson County$6.4M2005
Vanderbilt UniversityNashville, Davidson County$5.4M2009
Vanderbilt University Medical CenterNashville, Davidson County$5.3M2020
Vanderbilt UniversityNashville, Davidson County$5M2002
Vanderbilt UniversityNashville, Davidson County$4.5M1989
Vanderbilt University Medical CenterNashville, Davidson County$4.3M2019
Vanderbilt University Medical CenterNashville, Davidson County$4.1M2014

Source: USAspending.gov. Past awards show who this program funds; they don't guarantee future awards.

About the program (93.242)

Mental Health Research Grants

How applications are judged

The following consideration will be used in determining projects to be funded: (1) Technical merit of the proposed project as determined by peer review; (2) Availability of funds; and (3) Relevance to program priorities.

Matching requirements

This program has no statutory formula. Matching requirements are not applicable to this assistance listing. MOE requirements are not applicable to this assistance listing.

Examples of funded projects

Not Applicable.

Program listing on SAM.gov

About the program (93.313)

NIH Office of Research on Women's Health — (NIH/ORWH)

How applications are judged

Submitted proposals are accepted for review and possible funding based on the eligibility Information specified in the NOFO.

Matching requirements

This program has no statutory formula. Matching requirements are not applicable to this assistance listing. MOE requirements are not applicable to this assistance listing.

Examples of funded projects

Not Applicable.

Program listing on SAM.gov

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