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National Institutes of Health · Department of Health and Human Services

Developing novel theory and methods for understanding the genetic architecture of complex human traits (R01 Clinical Trial Not Allowed)

Open

Deadline
Due Nov 5, 2026 · 29 days left
Award size
Not stated: see the official notice
Match ?
Not required · Work out your budget and match
Who can apply
Nonprofit without 501(c)(3), Tribal government, Public college or university, Private college or university, Special district (utility, fire, etc.), City or town government, County government, Larger business, Tribal organization, Small business, State government, School district, Nonprofit with 501(c)(3), and others named in the official notice
Where
Anywhere in the U.S., including Tennessee
Read the official notice Should we apply? Sign in to save

Before you apply: federal grants require an active SAM.gov registration (Unique Entity ID) and a Grants.gov account. The deadline is in 29 days. If your registration isn't already active, it may not be ready in time, so check it today. Get-ready checklist

How this fits you

  • Available in Warren County (nationwide program)
  • No match required
  • Past Tennessee awards on file: 183

Tell us who you are to see whether you're eligible.

Official notice: https://simpler.grants.gov/opportunity/e7274f1f-6c35-4794-b86f-38504861afbc · Printed from grantme.click/grants/803ae973-397c-476c-965b-e4a8f1490509

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More from National Institutes of Health

About this grant

The goal of this NOFO is to support applications for novel theory and methods development that enable better understanding of how genetic and non-genetic factors contribute to complex trait variation across individuals, families, and populations. Approaches should be interdisciplinary drawing from the natural and social sciences, account for interdependencies across scales of biological, social, and ecological organization, and make extensive use of theory, modeling, and validation with available large-scale datasets.

Who can apply, from the official notice

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Ask a partner for a letter

Your schedule, working back from the deadline

  1. Oct7
    Check that your SAM.gov registration is active (or start it now)
    Grants.gov: allow up to 10 business days for SAM registration, weeks or months if information isn't verified. It must be renewed every year. Grants.gov
  2. Oct15
    Ask partners for letters of support or commitment
    Suggested: partners need about three weeks to write and sign letters.
  3. Oct29
    Finish a complete draft for a final review
    Suggested: leave about a week for someone else to read the draft.
  4. Nov3
    Submit
    Grants.gov: submit at least 24–48 hours before the deadline: uploads fail, systems slow down, errors need fixing. Grants.gov blog
  5. Nov5
    Deadline
    From the funder.

Save this grant to put these dates in My grants and your private calendar.

Writing the need statement? Warren County facts with citations.

Who in Tennessee has won this program

57 awards to Tennessee groups in 3 counties since 1989 · 0 in Warren County. Largest shown:

Past winnerWhereAmountFiscal year
Vanderbilt University Medical CenterNashville, Davidson County$16.8M2020
Vanderbilt University Medical CenterNashville, Davidson County$14.9M spent that year2025
Vanderbilt UniversityNashville$14.8M spent that year2025
Vanderbilt University Medical CenterNashville, Davidson County$13.3M spent that year2025
Baptist Memorial Hospital-TiptonCovington, Tipton County$11.9M2014
Vanderbilt UniversityNashville, Davidson County$8.7M2001
Vanderbilt UniversityNashville, Davidson County$8.7M2006
Vanderbilt University Medical CenterNashville, Davidson County$8.1M2016
Vanderbilt UniversityNashville, Davidson County$8.1M2005
Vanderbilt University Medical CenterNashville, Davidson County$8M2018
Vanderbilt University Medical CenterNashville, Davidson County$7.4M2020
Vanderbilt University Medical CenterNashville, Davidson County$7M2020

Source: USAspending.gov, Federal Audit Clearinghouse. Past awards show who this program funds. They don't guarantee future awards.

Tennessee groups that got this money through Tennessee Department of Mental Health and Substance Abuse Services

This federal money also reaches local groups as pass-through grants. In Tennessee, Tennessee Department of Mental Health and Substance Abuse Services passes it on: watch that agency for applications, not the federal agency. 126 pass-through grants on file · 0 in Warren County. Largest shown:

Past winnerWhereThroughAmountFiscal year
Vanderbilt UniversityNashville, Davidson CountyVanderbilt University Medical Center$2.3M2023
St Jude Children's Research Hospital IncMemphis, Shelby CountyWeill Medical College of Cornell University$2.1M2026
Vanderbilt University Medical CenterNashville, Davidson CountyThe Trustees of Princeton University$1.6M2023
Vanderbilt University Medical CenterNashville, Davidson CountyUniversity of Alabama at Birmingham$1.5M2026
Vanderbilt UniversityNashville, Davidson CountyThe Pennsylvania State University$1.1M2026
Meharry Medical CollegeNashville, Davidson CountyVanderbilt University Medical Center$1.1M2023
Vanderbilt University Medical CenterNashville, Davidson CountyVanderbilt University$920K spent that year2025
Vanderbilt University Medical CenterNashville, Davidson CountyThe General Hospital Corporation$839K2026
Meharry Medical CollegeNashville, Davidson CountyVumc$813K spent that year2023
Vanderbilt UniversityNashville, Davidson CountyThe Pennsylvania State University$756K2025
Vanderbilt University Medical CenterNashville, Davidson CountyIcahn School of Medicine at Mount Sinai$734K2025
St. Jude Children's Research Hospital, Inc.Memphis, Shelby CountyCornell University$698K spent that year2023

Source: USAspending.gov pass-through reports (the first recipient reports each one of $30,000 or more).

About the federal program

Human Genome Research, also called “National Human Genome Research Institute”
Program number 93.172 (the federal Assistance Listing number) · U.S. Department of Health and Human Services, National Institutes of Health · Project grant

How applications are judged

In each year's official notice: read this year's.

Match

None required (federal program listing).

Examples of funded projects

Fiscal year 2025: Examples of research supported by NHGRI in FY 2025 include characterization of genes, sequencing, databases, and projects on the following list: https://reporter.nih.gov/search/KP6XtPborUWv7kYNeFlJSA/projects?shared=true Fiscal year 2026: Current projects supported by NHGRI include basic genomic science; functional and clinical variation; genomic medicine; technology development; computational genomics and data science; training programs; conferences; databases; determining the ethical, legal, and social implications (ELSI) of biomedical and behavioral research; as well as projects on the following list: https://reporter.nih.gov/search/PbojAWqEZ0aySDrGRZXHTg/projects?shared=true

This program on SAM.gov

About the federal program

Mental Health Research Grants
Program number 93.242 (the federal Assistance Listing number) · U.S. Department of Health and Human Services, National Institutes of Health · Cooperative agreement (a grant with close agency involvement), project grant, training

How applications are judged

The following consideration will be used in determining projects to be funded: (1) Technical merit of the proposed project as determined by peer review; (2) Availability of funds; and (3) Relevance to program priorities.

Match

None required (federal program listing).

This program on SAM.gov

About the federal program

Cancer Control, also called “Cancer Control Grants”
Program number 93.399 (the federal Assistance Listing number) · U.S. Department of Health and Human Services, National Institutes of Health · Project grant

How applications are judged

The major elements in evaluating proposals include assessments of: (1) The scientific merit and general significance of the proposed study and its objectives; (2) the technical adequacy of the experimental design and approach; (3) the competency of the proposed investigator or group to successfully pursue the project; (4) the adequacy of the available and proposed facilities and resources; (5) the necessity of the budget components requested in relation to the proposed project; and (6) the relevance and importance to announced program objectives.

Match

None required (federal program listing).

This program on SAM.gov

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