National Institutes of Health · Department of Health and Human Services
Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research (P50 Clinical Trial Optional)
Key facts
- Deadline
- Due May 25, 2028 · 596 days left
- Award size
- Not stated: see the official notice
- Match ?
- Not required · Work out your budget and match
- Who can apply
- Nonprofit without 501(c)(3), Nonprofit with 501(c)(3), County government, Small business, Special district (utility, fire, etc.), Tribal government, Private college or university, Larger business, City or town government, State government, Public college or university, School district, Tribal organization, and others named in the official notice
- Where
- Anywhere in the U.S., including Tennessee
Before you apply: federal grants require an active SAM.gov registration (Unique Entity ID) and a Grants.gov account. Registration is free but can take weeks, so start now, not when the deadline is close. Get-ready checklist
How this fits you
- Available in Tennessee (nationwide program)
- No match required
- Past Tennessee awards on file: 99
Tell us who you are to see whether you're eligible.
Official notice: https://simpler.grants.gov/opportunity/95d8c541-2ee0-40cc-960c-61b524d2babd · Printed from grantme.click/grants/78d6c077-9843-430a-b83b-421e815ac85b
View on Grants.gov Add deadline to my calendar
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About this grant
This notice of funding opportunity (NOFO) encourages applications for Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research. The National Institute of Mental Health (NIMH) seeks teams of integrative researchers working at different levels of analysis and employing novel, and creative experimental approaches to address high-risk, high-impact questions with the primary objectives of: (a) advancing basic brain and behavior research that will uncover underlying mechanisms that could provide the foundation for understanding mental disorders; (b) supporting the integration and translation of basic and clinical neuroscience research on severe mental illnesses; (c) advancing our understanding of the neurobehavioral mechanisms and trajectories of psychopathology that begin in development. This program is intended only for projects that could not be achieved using other, more standard grant mechanisms.
Who can apply, from the official notice
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Your schedule, working back from the deadline
- Oct7
Check that your SAM.gov registration is active (or start it now)
Grants.gov: allow up to 10 business days for SAM registration, weeks or months if information isn't verified. It must be renewed every year. Grants.gov - May4
Ask partners for letters of support or commitment
Suggested: partners need about three weeks to write and sign letters. - May18
Finish a complete draft for a final review
Suggested: leave about a week for someone else to read the draft. - May23
Submit
Grants.gov: submit at least 24–48 hours before the deadline: uploads fail, systems slow down, errors need fixing. Grants.gov blog - May25
Deadline
From the funder.
Save this grant to put these dates in My grants and your private calendar.
Who in Tennessee has won this program
26 awards to Tennessee groups in 2 counties since 1989. Largest shown:
| Past winner | Where | Amount | Fiscal year |
|---|---|---|---|
| Vanderbilt University Medical Center | Nashville, Davidson County | $14.9M spent that year | 2025 |
| Vanderbilt University | Nashville | $14.8M spent that year | 2025 |
| Vanderbilt University | Nashville, Davidson County | $8.7M | 2001 |
| Vanderbilt University | Nashville, Davidson County | $8.7M | 2006 |
| Vanderbilt University | Nashville, Davidson County | $8.1M | 2005 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $7.4M | 2020 |
| Vanderbilt University | Nashville, Davidson County | $6.8M | 2004 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $6.4M | 2005 |
| Vanderbilt University | Nashville, Davidson County | $5.4M | 2009 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $5.3M | 2020 |
| Vanderbilt University | Nashville, Davidson County | $5M | 2002 |
| Vanderbilt University | Nashville, Davidson County | $4.5M | 1989 |
Source: Federal Audit Clearinghouse, USAspending.gov. Past awards show who this program funds. They don't guarantee future awards.
Tennessee groups that got this money through Tennessee Department of Mental Health and Substance Abuse Services
This federal money also reaches local groups as pass-through grants. In Tennessee, Tennessee Department of Mental Health and Substance Abuse Services passes it on: watch that agency for applications, not the federal agency. 73 pass-through grants on file. Largest shown:
| Past winner | Where | Through | Amount | Fiscal year |
|---|---|---|---|---|
| Vanderbilt University Medical Center | Nashville, Davidson County | The Trustees of Princeton University | $1.6M | 2023 |
| Vanderbilt University | Nashville, Davidson County | The Pennsylvania State University | $1.1M | 2026 |
| Vanderbilt University Medical Center | Nashville, Davidson County | Vanderbilt University | $920K spent that year | 2025 |
| Vanderbilt University Medical Center | Nashville, Davidson County | The General Hospital Corporation | $839K | 2026 |
| Vanderbilt University | Nashville, Davidson County | The Pennsylvania State University | $756K | 2025 |
| Vanderbilt University Medical Center | Nashville, Davidson County | Icahn School of Medicine at Mount Sinai | $734K | 2025 |
| Vanderbilt University | Nashville, Davidson County | Vanderbilt University Medical Center | $560K | 2023 |
| University of Tennessee | Memphis, Shelby County | University of Puerto Rico | $553K | 2026 |
| Vanderbilt University | Nashville | Vumc | $500K spent that year | 2024 |
| Vanderbilt University | Nashville | Vanderbilt University Medical Center | $493K spent that year | 2025 |
| Vanderbilt University Medical Center | Nashville, Davidson County | Icahn School of Medicine at Mount Sinai | $487K spent that year | 2025 |
| Vanderbilt University Medical Center | Nashville, Davidson County | Icahn School of Medicine at Mount Sinai | $462K | 2024 |
Source: USAspending.gov pass-through reports (the first recipient reports each one of $30,000 or more).
About the federal program
Mental Health Research Grants
Program number 93.242 (the federal Assistance Listing number) · U.S. Department of Health and Human Services, National Institutes of Health · Cooperative agreement (a grant with close agency involvement), project grant, training
How applications are judged
The following consideration will be used in determining projects to be funded: (1) Technical merit of the proposed project as determined by peer review; (2) Availability of funds; and (3) Relevance to program priorities.
Match
None required (federal program listing).