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National Institutes of Health · Department of Health and Human Services

Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R21 Clinical Trial Not Allowed)

Open · Opportunity PAR-25-286 · Assistance Listing 93.242

Key facts

Deadline
Due Jan 7, 2028 · 457 days left
Award size
Not specified — see notice
Cost share / match ?
Not required
Who can apply
County government, Public college or university, Other (see eligibility), Small business, Tribal organization, School district, Tribal government, State government, Special district (utility, fire, etc.), City or town government, Nonprofit with 501(c)(3), Private college or university, Larger business, Nonprofit without 501(c)(3)
Where
Anywhere in the U.S., including Tennessee

Before you apply: federal grants require an active SAM.gov registration (Unique Entity ID) and a Grants.gov account. Registration is free but can take weeks, so start now, not when the deadline is close. Grant-ready checklist

How this fits you

  • Available in Tennessee (nationwide program)
  • No cost share required
  • Tennessee recipients since 2023: 22

Tell us who you are to see whether you're eligible.

More from National Institutes of Health

Read the official notice View on Grants.gov Add deadline to my calendar Sign in to save

About this grant

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage applications seeking to develop the next generation of brain stimulation devices for treating mental health disorders. Applications are sought that will either 1) develop novel brain stimulation devices or 2) significantly enhance, by means of hardware/software improvements, the effectiveness of brain stimulation devices that are currently U.S. Food and Drug Administration (FDA)-approved or cleared. Novel devices should move beyond existing electrical/magnetic stimulation and develop new stimulation techniques capable of increased spatiotemporal precision as well as multi-focal, closed-loop approaches. Applications seeking to develop new capabilities should focus on significant enhancement of the spatial resolution, depth of delivery, and/or precision of the device. Incremental changes to existing devices (e.g., software updates)are not within the scope of this announcement. Applications should be submitted by multi-disciplinary teams with a variety of expertise including systems neuroscience, engineering, clinical, and regulatory affairs.

Eligibility (from the notice)

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Who in Tennessee has won this program

22 awards to Tennessee recipients in 2 counties since federal FY2023. Largest shown:

Past Tennessee recipients
RecipientWhereAmountFY
Vanderbilt UniversityNashville, Davidson County$8.7M2001
Vanderbilt UniversityNashville, Davidson County$8.7M2006
Vanderbilt UniversityNashville, Davidson County$8.1M2005
Vanderbilt University Medical CenterNashville, Davidson County$7.4M2020
Vanderbilt UniversityNashville, Davidson County$6.8M2004
Vanderbilt University Medical CenterNashville, Davidson County$6.4M2005
Vanderbilt UniversityNashville, Davidson County$5.4M2009
Vanderbilt University Medical CenterNashville, Davidson County$5.3M2020
Vanderbilt UniversityNashville, Davidson County$5M2002
Vanderbilt UniversityNashville, Davidson County$4.5M1989
Vanderbilt University Medical CenterNashville, Davidson County$4.3M2019
Vanderbilt University Medical CenterNashville, Davidson County$4.1M2014

Source: USAspending.gov. Past awards show who this program funds; they don't guarantee future awards.

About the program (93.242)

Mental Health Research Grants

How applications are judged

The following consideration will be used in determining projects to be funded: (1) Technical merit of the proposed project as determined by peer review; (2) Availability of funds; and (3) Relevance to program priorities.

Matching requirements

This program has no statutory formula. Matching requirements are not applicable to this assistance listing. MOE requirements are not applicable to this assistance listing.

Examples of funded projects

Not Applicable.

Program listing on SAM.gov

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