National Institutes of Health · Department of Health and Human Services
Centers of Excellence in Genomic Science (CEGS)
In short: National Institutes of Health expects to make 2 awards. Open to many kinds of groups. See who can apply.
Key facts
- Deadline
- The funder's estimated date (Jun 24, 2026) has passed. Check the official notice Estimate, not confirmed by the funder ?
- Award size
- Not stated: see the official notice
- Total available
- $5M · about 2 awards
- Match ?
- Not required · Work out your budget and match
- Who can apply
- Nonprofit with 501(c)(3), Public college or university, Private college or university, Nonprofit without 501(c)(3), Tribal organization, City or town government, Special district (utility, fire, etc.), School district, State government, County government, Tribal government, Small business, Larger business, and others named in the official notice
- Where
- Anywhere in the U.S., including Tennessee
Opening soon: the funder has announced this grant, but you can't apply yet. Use the time to get ready and check whether it fits.
Before you apply: federal grants require an active SAM.gov registration (Unique Entity ID) and a Grants.gov account. Registration is free but can take weeks, so start now, not when the deadline is close. Get-ready checklist
How this fits you
- Available in Madison County (nationwide program)
- No match required
- Past Tennessee awards on file: 72
Tell us who you are to see whether you're eligible.
About this grant
The National Human Genome Research Institute (NHGRI) intends to promote an initiative by publishing a Notice of Funding Opportunity (NOFO) to solicit applications for the Centers of Excellence in Genomic Science (CEGS) program. The purpose of the CEGS program is to bring together interdisciplinary teams of investigators to form tightly focused, well-integrated projects that address challenging biomedical questions from a genomics perspective. CEGS are expected to develop highly innovative novel concepts, methods, approaches, tools, and technologies to address these questions and achieve a transformative advance not likely developed by standard R01s or other projects over the same timeframe. Importantly, each CEGS will address a critical issue in genomic science, genomic medicine, computational genomics, or an issue that cuts across more than one of these areas. Given these goals, each center is required to have outstanding scientific plans and management strategies that balance a high level of risk with the potential for high payoff. Additional goals of the CEGS program include broadening the pool of researchers able to work in or use genomics, and dissemination of CEGS developed methods and tools to the broader research community.
In February 2024 a mixed-methods evaluation (see evaluation report) was completed to assess the outcomes of this flagship NHGRI program. The evaluation highlighted several strengths such as the high-risk, high-reward nature of the CEGS funding mechanism, a focus on technology development linked to biological questions, and the funding of several breakthrough resources and approaches that have surpassed genomics to stimulate many research areas. Suggestions for improvements, such as widening the focus and increasing outreach opportunities, will be addressed in this renewal.
Who can apply, from the official notice
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Official notice: https://simpler.grants.gov/opportunity/e9f03c13-cda6-4177-958e-33f2d783facc · Printed from grantme.click/grants/4e130042-bb18-4796-aa24-b72902a4da65
Writing the need statement? Madison County facts with citations.
Who in Tennessee has won this program
28 awards to Tennessee groups in 2 counties since 2016 · 0 in Madison County. Largest shown:
| Past winner | Where | Amount | Fiscal year |
|---|---|---|---|
| Vanderbilt University Medical Center | Nashville, Davidson County | $16.8M | 2020 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $13.3M spent that year | 2025 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $8.1M | 2016 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $8M | 2018 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $7M | 2020 |
| St Jude Children's Research Hospital Inc | Memphis, Shelby County | $5.2M | 2018 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $4.6M | 2022 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $4.5M | 2023 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $4.4M | 2024 |
| Vanderbilt University | Nashville, Davidson County | $4.3M | 2016 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $4.3M | 2022 |
| Meharry Medical College | Nashville, Davidson County | $4.2M | 2023 |
Source: USAspending.gov; Federal Audit Clearinghouse. Past awards show who this program funds. They don't guarantee future awards.
Tennessee groups that got this money through a state agency or another organization
This federal money also reaches local groups as pass-through grants. 44 pass-through grants on file · 0 in Madison County. Largest shown:
| Past winner | Where | Through | Amount | Fiscal year |
|---|---|---|---|---|
| Vanderbilt University | Nashville, Davidson County | Vanderbilt University Medical Center | $2.3M | 2023 |
| St Jude Children's Research Hospital Inc | Memphis, Shelby County | Weill Medical College of Cornell University | $2.1M | 2026 |
| Vanderbilt University Medical Center | Nashville, Davidson County | University of Alabama at Birmingham | $1.5M | 2026 |
| Meharry Medical College | Nashville, Davidson County | Vanderbilt University Medical Center | $1.1M | 2023 |
| Meharry Medical College | Nashville, Davidson County | Vumc | $813K spent that year | 2023 |
| St. Jude Children's Research Hospital, Inc. | Memphis, Shelby County | Cornell University | $698K spent that year | 2023 |
| Vanderbilt University Medical Center | Nashville, Davidson County | University of North Carolina at Chapel Hill | $669K | 2023 |
| Meharry Medical College | Nashville, Davidson County | Vanderbilt University Medical Center | $545K | 2023 |
| Meharry Medical College | Nashville, Davidson County | Vanderbilt University Medical Center | $536K | 2023 |
| Vanderbilt University Medical Center | Nashville, Davidson County | Broad Institute of Mit and Harvard | $455K spent that year | 2025 |
| St Jude Children's Research Hospital Inc | Memphis, Shelby County | The Leland Stanford Junior University | $444K | 2024 |
| St. Jude Children's Research Hospital, Inc. | Memphis, Shelby County | Stanford University | $432K spent that year | 2025 |
Source: USAspending.gov pass-through reports (the first recipient reports each one of $30,000 or more).
Similar grants open or opening soon
From other funders, about the same kind of work in Madison County.
- Centers of Excellence in Healthcare Quality and Safety · Centers for Disease Control - NCEZID · Opens Nov 5, 2026 · due about Jan 4, 2027 Estimate, not confirmed by the funder
- CDC National Centers of Excellence in Youth Violence Prevention (YVPCs): Rigorous Evaluation of Prevention Approaches to Prevent and Reduce Youth Violence · Centers for Disease Control and Prevention - ERA · Due about Dec 1, 2026 Estimate, not confirmed by the funder
- Regional Excellence for Access to Comprehensive Care for Hemophilia Networks (REACH Networks) · Health Resources and Services Administration · Opens Nov 6, 2026 · due about Dec 22, 2026 Estimate, not confirmed by the funder
- Centers of Excellence (COE) · Health Resources and Services Administration · Opens Dec 2, 2026 · due about Feb 2, 2027 Estimate, not confirmed by the funder
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About the federal program
Human Genome Research, also called “National Human Genome Research Institute”
Program number 93.172 (the federal Assistance Listing number) · U.S. Department of Health and Human Services, National Institutes of Health · Project grant
How applications are judged
In each year's official notice: read this year's.
Match
None required (federal program listing).
Examples of funded projects
Fiscal year 2025: Examples of research supported by NHGRI in FY 2025 include characterization of genes, sequencing, databases, and projects on the following list: https://reporter.nih.gov/search/KP6XtPborUWv7kYNeFlJSA/projects?shared=true
Fiscal year 2026: Current projects supported by NHGRI include basic genomic science; functional and clinical variation; genomic medicine; technology development; computational genomics and data science; training programs; conferences; databases; determining the ethical, legal, and social implications (ELSI) of biomedical and behavioral research; as well as projects on the following list:
https://reporter.nih.gov/search/PbojAWqEZ0aySDrGRZXHTg/projects?shared=true