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Bureau of Global Health Security and Diplomacy · Department of State

Advancing Global Health

Open

In short: Bureau of Global Health Security and Diplomacy expects to make 100 awards of $500,000 to $250 million. Anyone can apply.

Key facts

Deadline
Due Feb 14, 2027 · 128 days left
Award size
$500K – $250M
Total available
$2147.5M · about 100 awards
Match ?
Not required · Work out your budget and match
Who can apply
Anyone (unrestricted)
Where
Anywhere in the U.S., including Tennessee

How this fits you

  • Available in Tennessee (nationwide program)
  • No match required

Tell us who you are to see whether you're eligible.

About this grant

The Department of State invites eligible applicants to advance the America First Global Health Strategy, which aims to save lives, strengthen health systems, enhance efficiency, foster self-reliance, and ensure U.S. investments benefit American safety, strength, and prosperity. This Annual Program Statement (APS) establishes a supplemental framework through which the Department of State may identify and support projects that complement, extend, and/or fill identified gaps in the implementation of these bilateral MOUs. Through specific Addenda, the Department will signal priorities and needs. This APS provides the standard application instructions for the submission of all Statements of Interest (SOIs) to these specific Addenda. GHSD will collaborate with Embassies and other Department of State Bureaus and Offices to post specific funding opportunities through Addenda to this APS that address health challenges and priorities of importance.

Who can apply, from the official notice

Please see APS instructions for eligibility criteria.

View on Grants.gov Add deadline to my calendar

Ask a partner for a letter

Your schedule, working back from the deadline

  1. Oct9
    Check that your SAM.gov registration is active (or start it now)
    Grants.gov: allow up to 10 business days for SAM registration, weeks or months if information isn't verified. It must be renewed every year. Grants.gov
  2. Jan24
    Ask partners for letters of support or commitment
    Suggested: partners need about three weeks to write and sign letters.
  3. Feb8
    Finish a complete draft for a final review
    Suggested: leave about a week for someone else to read the draft.
  4. Feb12
    Submit
    Grants.gov: submit at least 24–48 hours before the deadline: uploads fail, systems slow down, errors need fixing. Grants.gov blog
  5. Feb14
    Deadline
    From the funder.

Save this grant to put these dates in My grants and your private calendar.

What the official notice requires

Pulled from the official notice DFOP0017890_Advancing_Global_Health_APS_Round_2a_QA.pdf (80 pages) so you can see the requirements at a glance. Each item shows the notice's own words. Open the page to read it in context.

Award size and project length

  • Award amounts here are per year · p. 62
    “The Malawi Addendum states up to 4 awards totaling up to $35M annually.” Open page 62
  • Project period: 5 years · p. 73
    “The period of performance for the proposed project should be 5 years or less, including any non-competitive continuations.” Open page 73

Registrations you need first (3)

  • Grants.gov · p. 2
    “Submission Platform Clarifications (Grants.gov and MyGrants) The Department of State has received a number of questions regarding submission requirements across Grants.gov and MyGrants, particularly related to required forms at the SOI stage.” Open page 2
  • SAM.gov · p. 77
    “Organizations are required to have an active SAM.gov registration to apply through grants.gov. 12.” Open page 77
  • Unique Entity ID (UEI) · p. 79
    “Please advise on the need to ensure that an individual registered in Mygrants requires a formal linkage to the organization (beyond a UEI number).” Open page 79

Registration is free but can take weeks, so start now, not when the deadline is close. Get-ready checklist

What to submit

  • Form SF-424 · p. 2
    “Standard federal assistance forms (e.g., SF-424, SF-424A, SF-424B) are not required at the SOI stage and are not part of the merit review.” Open page 2
  • Form SF-424A · p. 2
    “Standard federal assistance forms (e.g., SF-424, SF-424A, SF-424B) are not required at the SOI stage and are not part of the merit review.” Open page 2
  • Form SF-424B · p. 2
    “Standard federal assistance forms (e.g., SF-424, SF-424A, SF-424B) are not required at the SOI stage and are not part of the merit review.” Open page 2
  • Memorandum of understanding (MOU) · p. 3
    “Detailed knowledge of specific MOUs is not required to submit a competitive SOI.” Open page 3
  • Letters of support or commitment · p. 7
    “At the SOI stage, how important is it to name Nigerian partners or include letters of support from Nigerian government institutions, universities, professional associations, faith/community-based providers, or local organizations?” Open page 7
  • Evaluation plan · p. 54
    “A detailed evaluation plan is not required at the SOI stage. 127.” Open page 54

Length limits

  • For: 5 pages max · p. 76
    “For the 5-page limit, does the partner roles section count toward the page limit if we keep it in the narrative, or can we move it to an annex?” Open page 76

Formatting rules

  • 10-point font · p. 1
    “Given the nature of tables and charts, font sizes as small as 10-point are acceptable for these elements.” Open page 1

Cost share or match

  • Cost share / match · p. 35
    “The APS states that cost sharing or matching is not required and will not be evaluated as part of the merit review process, but it also asks for a description of 'Resource Contributions and/or Cost Share' in the Phase 1 SOI format.” Open page 35
  • Cost share / match · p. 35
    “(Proposal Evaluation, Section B.2/Cost Sharing or Matching) Cost sharing or matching is not required.” Open page 35
  • Cost share / match · p. 36
    “(Proposal Evaluation, Section B.2/Cost Sharing or Matching) No cost sharing or non-federal resource contributions are not required.” Open page 36
  • Cost share / match · p. 39
    “Cost share is not required unless specifically stated, and applicants should describe any proposed resource contributions clearly and realistically. 15.” Open page 39

Mistakes that get applications rejected (7)

  • Could get your application rejected: Review Process Any SF-424 or related forms submitted as part of a Grants.gov package at the SOI stage will... · p. 3
    “Review Process Any SF-424 or related forms submitted as part of a Grants.gov package at the SOI stage will not be reviewed or evaluated.” Open page 3
  • Could get your application rejected: The APS states that cost sharing or matching is not required and will not be evaluated as part of the... · p. 35
    “The APS states that cost sharing or matching is not required and will not be evaluated as part of the merit review process, but it also asks for a description of 'Resource Contributions and/or Cost Share' in the Phase 1 SOI format.” Open page 35
  • Could get your application rejected: While applicants may propose cost share or matching, cost-sharing/matching will not be evaluated as part... · p. 35
    “While applicants may propose cost share or matching, cost-sharing/matching will not be evaluated as part of the merit review process.” Open page 35
  • Could get your application rejected: Is there a possibility that a partner is awarded this grant and disqualified by the MOH? · p. 53
    “Is there a possibility that a partner is awarded this grant and disqualified by the MOH?” Open page 53
  • Could get your application rejected: While cost sharing or matching is not required and will not be evaluated as part of the merit review... · p. 60
    “While cost sharing or matching is not required and will not be evaluated as part of the merit review process, organizations may describe how existing assets and resources support the feasibility and sustainability of the proposed approach.” Open page 60
  • Could get your application rejected: Interventions that create parallel structures or indefinite dependence on external technical assistance... · p. 70
    “Interventions that create parallel structures or indefinite dependence on external technical assistance will not be considered. 48.” Open page 70
  • Could get your application rejected: GHSD is not specifying requirements for how to fill out these forms that will not be reviewed. · p. 79
    “GHSD is not specifying requirements for how to fill out these forms that will not be reviewed.” Open page 79

Files from the official listing

The notice, forms and templates the agency attached. Some programs ask for a letter of intent or a form before the full application.

Similar grants open or opening soon

From other funders, about the same kind of work.

About the federal program

The U.S. President's Emergency Plan for AIDS Relief Programs, also called “(PEPFAR)”
Program number 19.029 (the federal Assistance Listing number) · U.S. Department of State, Office of U.S. Global AIDS Coordinator · Cooperative agreement (a grant with close agency involvement), project grant

How applications are judged

In each year's official notice: read this year's.

Match

None required (federal program listing).

This program on SAM.gov

Something wrong on this page? Tell us
What's wrong?

Source: Federal grants from Grants.gov · the official federal record. Last checked by GrantMe Oct 9, 2026.

Reference numbers: official notice number DFOP0017890 · program number 19.029