Resource-Related Research Projects Cooperative Agreements in Aging and/or Alzheimer's Disease (AD) and Alzheimer's Disease-Related Dementias (ADRD) Research

The National Institute on Aging (NIA) intends to publish a Notice of Funding Opportunity (NOFO) to invite new, renewal, and revision applications, and their resubmissions, for U24 Research Resource/Infrastructure cooperative agreements that support large-scale, complex research programs focused on aging and/or Alzheimer's disease (AD) and Alzheimer's disease-related dementias (ADRD) research. It is anticipated that such programs will likely involve a team of investigators from a single institution, or a consortium of institutions, and align with the mission and research priorities of NIA. If submitting renewal or revision applications, the research objectives and scope of applications submitted through this NOFO must adhere to the requirements outlined in the parent NOFO under which the original application was funded. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO intends to utilize the U24 activity code. Applicants should be aware that NIA anticipates funding only a limited number of meritorious applications under this announcement. Consultation with IC staff is strongly encouraged prior to the submission of an application to discuss the responsiveness of their proposed research to this NOFO and its relevance to NIA’s programmatic priorities.

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.

The major elements in evaluating proposals include assessments of: the scientific merit and general significance of the proposed study and its objectives; the technical adequacy of the experimental design and approach; the competency of the proposed investigator or group to successfully pursue the project; the adequacy of the available and proposed facilities and resources; the necessity of the budget components requested in relation to the proposed project; and the relevance and importance to announced program objectives. The following criteria will be used in considering the scientific and technical merit of SBIR/STTR Phase I grant applications: (1) The soundness and technical merit of the proposed approach; (2) the qualifications of the proposed principal investigator, supporting staff, and consultants; (3) the technological innovation of the proposed research; (4) the potential of the proposed research for commercial application; (5) the appropriateness of the budget requested; (6) the adequacy and suitability of the facilities and research; and (7) where applicable, the adequacy of assurances detailing the proposed means for (a) safeguarding human or animal subjects, and/or (b) protecting against or minimizing any adverse effect on the environment. Phase II grant applications will be reviewed based upon the following criteria: (1) The degree to which the Phase I objectives were met and feasibility demonstrated; (2) the scientific and technical merit of the proposed...