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National Institutes of Health · Department of Health and Human Services

NHLBI Emerging Investigator Award (EIA) (R35 Clinical Trial Optional)

Open

Key facts

Deadline
Due Apr 28, 2027 · 203 days left
Award size
Not stated: see the official notice
Match ?
Not required · Work out your budget and match
Who can apply
Tribal government, Special district (utility, fire, etc.), Larger business, State government, Small business, City or town government, County government, Nonprofit with 501(c)(3), Nonprofit without 501(c)(3), Tribal organization, School district, Public college or university, Private college or university, and others named in the official notice
Where
Anywhere in the U.S., including Tennessee

Before you apply: federal grants require an active SAM.gov registration (Unique Entity ID) and a Grants.gov account. Registration is free but can take weeks, so start now, not when the deadline is close. Get-ready checklist

How this fits you

  • Available in Tennessee (nationwide program)
  • No match required
  • Past Tennessee awards on file: 104

Tell us who you are to see whether you're eligible.

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More from National Institutes of Health

About this grant

The purpose of the NHLBI Emerging Investigator Award (EIA) is to promote scientific productivity and innovation by providing long-term support and increased flexibility to experienced Program Directors/Principal Investigators (PDs/PIs) who are currently PDs/PIs on at least two NHLBI R01-equivalent awards and whose outstanding record of research demonstrates their ability to make major contributions to heart, lung, blood and sleep (HLBS) research. The EIA is intended to support a research program, rather than a research project, by providing the primary and most likely sole source of NHLBI funding on individual grant awards. The EIA will support the research program of NHLBI-funded investigators for up to seven years. The EIA will provide investigators increased freedom to conduct research that breaks new ground or extends previous discoveries in new directions. It will also allow PDs/PIs to take greater risks and to pursue research that requires a longer timeframe. Research supported by the EIA must be within the scope of the NHLBI mission (http://www.nhlbi.nih.gov/about/org/mission).

Who can apply, from the official notice

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Ask a partner for a letter

Your schedule, working back from the deadline

  1. Oct7
    Check that your SAM.gov registration is active (or start it now)
    Grants.gov: allow up to 10 business days for SAM registration, weeks or months if information isn't verified. It must be renewed every year. Grants.gov
  2. Apr7
    Ask partners for letters of support or commitment
    Suggested: partners need about three weeks to write and sign letters.
  3. Apr21
    Finish a complete draft for a final review
    Suggested: leave about a week for someone else to read the draft.
  4. Apr26
    Submit
    Grants.gov: submit at least 24–48 hours before the deadline: uploads fail, systems slow down, errors need fixing. Grants.gov blog
  5. Apr28
    Deadline
    From the funder.

Save this grant to put these dates in My grants and your private calendar.

Who in Tennessee has won this program

61 awards to Tennessee groups in 2 counties since 1977. Largest shown:

Past Tennessee winners
Past winnerWhereAmountFiscal year
St Jude Children's Research Hospital IncMemphis, Shelby County$28.2M1997
Vanderbilt University Medical CenterNashville, Davidson County$24.7M2014
Vanderbilt University Medical CenterNashville, Davidson County$21.8M2012
Vanderbilt University Medical CenterNashville, Davidson County$21.6M2010
Vanderbilt UniversityNashville, Davidson County$15.5M2014
Vanderbilt University Medical CenterNashville, Davidson County$12.3M2016
University of TennesseeMemphis, Shelby County$11.3M1977
Vanderbilt University Medical CenterNashville, Davidson County$8.1M2022
Vanderbilt University Medical CenterNashville, Davidson County$7.1M2019
Vanderbilt University Medical CenterNashville, Davidson County$6.8M2007
Vanderbilt University Medical CenterNashville, Davidson County$6.7M2010
Vanderbilt University Medical CenterNashville, Davidson County$6.3M2008

Source: USAspending.gov. Past awards show who this program funds. They don't guarantee future awards.

Tennessee groups that got this money through a state agency or another organization

This federal money also reaches local groups as pass-through grants. 43 pass-through grants on file. Largest shown:

Tennessee pass-through grant winners
Past winnerWhereThroughAmountFiscal year
Vanderbilt University Medical CenterNashville, Davidson CountyTrustees of Boston University$4.6M2023
Vanderbilt University Medical CenterNashville, Davidson CountyRegents of the University of Michigan$3.4M2025
Vanderbilt UniversityNashville, Davidson CountyVanderbilt University Medical Center$1.3M2023
Vanderbilt UniversityNashville, Davidson CountyPurdue University$1.2M2024
Vanderbilt University Medical CenterNashville, Davidson CountyRegents of the University of California, San Francisco, the$1M2023
Vanderbilt University Medical CenterNashville, Davidson CountyYale Univ$938K2023
Vanderbilt University Medical CenterNashville, Davidson CountyThe Children's Hospital of Philadelphia$810K2025
Vanderbilt University Medical CenterNashville, Davidson CountyUniversity of Pittsburgh - of the Commonwealth System of Higher Education$764K2026
St Jude Children's Research Hospital IncMemphis, Shelby CountyIcahn School of Medicine at Mount Sinai$763K2024
Vanderbilt University Medical CenterNashville, Davidson CountyThe Children's Hospital of Philadelphia$757K2026
Vanderbilt University Medical CenterNashville, Davidson CountyTranslational Genomics Research Institute$729K2024
Vanderbilt University Medical CenterNashville, Davidson CountyUniversity of North Carolina at Chapel Hill$698K2023

Source: USAspending.gov pass-through reports (the first recipient reports each one of $30,000 or more).

About the federal program

National Center on Sleep Disorders Research
Program number 93.233 (the federal Assistance Listing number) · U.S. Department of Health and Human Services, National Institutes of Health · Project grant

How applications are judged

The major elements in evaluating proposals include assessments of: (1) The scientific merit and general significance of the proposed study and its objectives; (2) the technical adequacy of the experimental design and approach; (3) the competency of the proposed investigator or group to successfully pursue the project; (4) the adequacy of the available and proposed facilities and resources; (5) the necessity of the budget components requested in relation to the proposed project; and (6) the relevance and importance to announced program objectives. The following criteria will be used in considering the scientific and technical merit of SBIR/STTR Phase I grant applications: (1) The soundness and technical merit of the proposed approach; (2) the importance of the problem the proposed research will address; (3) the qualifications of the proposed principal investigator, supporting staff, and consultants; (4) the technological innovation of the proposed research; (5) the potential of the proposed research for commercial application; (6) the appropriateness of the budget requested; (7) the adequacy and suitability of the facilities and research environment; (8) the adequacy of plans to include both genders and minorities and their subgroups as appropriate for the scientific goals of the research. Plans for the recruitment and retention of subjects will be evaluated; and (9) where applicable, the adequacy of assurances detailing the proposed means for (a) safeguarding human or...

Match

None required (federal program listing).

This program on SAM.gov

About the federal program

Cardiovascular Diseases Research
Program number 93.837 (the federal Assistance Listing number) · U.S. Department of Health and Human Services, National Institutes of Health · Project grant

How applications are judged

The major elements in evaluating proposals include assessments of: (1) the scientific merit and general significance of the proposed study and its objectives; (2) the technical adequacy of the experimental design and approach; (3) the competency of the proposed investigator or group to successfully pursue the project; (4) the adequacy of the available and proposed facilities and resources; (5) the necessity of the budget components requested in relation to the proposed project; and (6) the relevance and importance to announced program objectives. The following criteria will be used in considering the scientific and technical merit of SBIR/STTR Phase I grant applications: (1) the soundness and technical merit of the proposed approach; (2) the importance of the problem the proposed research will address; (3) the qualifications of the proposed principal investigator, supporting staff, and consultants; (4) the technological innovation of the proposed research; (5) the potential of the proposed research for commercial application; (6) the appropriateness of the budget requested; (7) the adequacy and suitability of the facilities and research environment; and (8) the adequacy of plans to include both genders and minorities and their subgroups as appropriate for the scientific goals of the research. Plans for the recruitment and retention of subjects will be evaluated; and (9) where applicable, the adequacy of assurances detailing the proposed means for (a) safeguarding human or...

Match

None required (federal program listing).

This program on SAM.gov

About the federal program

Lung Diseases Research
Program number 93.838 (the federal Assistance Listing number) · U.S. Department of Health and Human Services, National Institutes of Health · Project grant

How applications are judged

The major elements in evaluating proposals include assessments of: (1) The scientific merit and general significance of the proposed study and its objectives; (2) the technical adequacy of the experimental design and approach; (3) the competency of the proposed investigator or group to successfully pursue the project; (4) the adequacy of the available and proposed facilities and resources; (5) the necessity of the budget components requested in relation to the proposed project; and (6) the relevance and importance to announced program objectives. The following criteria will be used in considering the scientific and technical merit of SBIR/STTR Phase I grant applications: (1) The soundness and technical merit of the proposed approach; (2) the importance of the problem the proposed research will address; (3) the qualifications of the proposed principal investigator, supporting staff, and consultants; (4) the scientific, technical, or technological innovation of the proposed research; (5) the potential of the proposed research for commercial application; (6) the appropriateness of the budget requested; (7) the adequacy and suitability of the facilities and research environment; (8) the adequacy of plans to include both genders and minorities and their subgroups as appropriate for the scientific goals of the research. Plans for the recruitment and retention of subjects will be evaluated; and (9) where applicable, the adequacy of assurances detailing the proposed means for (a)...

Match

None required (federal program listing).

This program on SAM.gov

About the federal program

Blood Diseases and Resources Research, also called “Division of Blood Diseases and Resources (DBDR)”
Program number 93.839 (the federal Assistance Listing number) · U.S. Department of Health and Human Services, National Institutes of Health · Project grant

How applications are judged

The major elements in evaluating proposals include assessments of: (1) The scientific merit and general significance of the proposed study and its objectives; (2) the technical adequacy of the experimental design and approach; (3) the competency of the proposed investigator or group to successfully pursue the project; (4) the adequacy of the available and proposed facilities and resources; (5) the necessity of the budget components requested in relation to the proposed project; and (6) the relevance and importance to announced program objectives. The following criteria will be used in considering the scientific and technical merit of SBIR/STTR Phase I grant applications: (1) The soundness and technical merit of the proposed approach; (2) the importance of the problem the proposed research will address; (3) the qualifications of the proposed principal investigator, supporting staff, and consultants; (4) the technological innovation of the proposed research; (5) the potential of the proposed research for commercial application; (6) the appropriateness of the budget requested; (7) the adequacy and suitability of the facilities and research environment; (8) the adequacy of plans to include both genders and minorities and their subgroups as appropriate for the scientific goals of the research. Plans for the recruitment and retention of subjects will be evaluated; and (9) where applicable, the adequacy of assurances detailing the proposed means for (a) safeguarding human or...

Match

None required (federal program listing).

This program on SAM.gov

About the federal program

Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders
Program number 93.840 (the federal Assistance Listing number) · U.S. Department of Health and Human Services, National Institutes of Health · Project grant

How applications are judged

The major elements in evaluating proposals include assessments of: (1) The scientific merit and general significance of the proposed study and its objectives; (2)the technical adequacy of the experimental design and approach; (3) the competency of the proposed investigator or group to successfully pursue the project; (4) the adequacy of the available and proposed facilities and resources; (5) the necessity of the budget components requested in relation to the proposed project; and (6) the relevance and importance to announced program objectives. The following criteria will be used in considering the scientific and technical merit of SBIR/STTR Phase I grant applications: (1) The soundness and technical merit of the proposed approach; (2) the importance of the problem the proposed research will address; (3) the qualifications of the proposed principal investigator, supporting staff, and consultants; (4) the technological innovation of the proposed research; (5) the potential of the proposed research for commercial application; (6) the appropriateness of the budget requested; (7) the adequacy and suitability of the facilities and research environment; and (8) where applicable, the adequacy of assurances detailing the proposed means for (a) safeguarding human or animal subjects, and/or (b) protecting against or minimizing any adverse effect on the environment. Phase II grant applications will be reviewed based upon the following criteria: (1) The degree to which the Phase I...

Match

None required (federal program listing).

This program on SAM.gov

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