National Institutes of Health · Department of Health and Human Services
Cellular Senescence Network (SenNet): SenNet Technology Projects (SenTecs) (UG3/UH3 Clinical Trial Not Allowed)
In short: National Institutes of Health expects to make 15 awards. Open to many kinds of groups. See who can apply.
Key facts
- Deadline
- Due Nov 23, 2026 · 45 days left
- Award size
- Not stated: see the official notice
- Total available
- $6M · about 15 awards
- Match ?
- Not required · Work out your budget and match
- Who can apply
- Public college or university, State government, County government, City or town government, Special district (utility, fire, etc.), Tribal government, Private college or university, Nonprofit with 501(c)(3), Larger business, Tribal organization, Small business, Nonprofit without 501(c)(3), School district, and others named in the official notice
- Where
- Anywhere in the U.S., including Tennessee
What changed
- Status changed from opening soon to open (seen Oct 9, 2026)
- Deadline moved from Dec 9, 2025 to Nov 23, 2026 (seen Oct 9, 2026)
- Deadline confirmed by the funder (seen Oct 9, 2026)
- Opening date moved to Oct 9, 2026 (seen Oct 9, 2026)
- Who can apply changed: check the eligibility section (seen Oct 9, 2026)
Before you apply: federal grants require an active SAM.gov registration (Unique Entity ID) and a Grants.gov account. Registration is free but can take weeks, so start now, not when the deadline is close. Get-ready checklist
How this fits you
- Available in Madison County (nationwide program)
- No match required
- Past Tennessee awards on file: 82
Tell us who you are to see whether you're eligible.
About this grant
The purpose of this Notice of Funding Opportunity (NOFO) is to solicit the development of innovative senescence technologies (SenTecs), or the adaptation of existing technologies focused on identification, characterization and understanding the biological consequences of senescent cell (SnC) heterogeneity in the context of the tissue environments and secretomes to facilitate novel strategies for modulating SnCs in vivo and for predicting the outcomes of targeting SnCs in human aging and in disease conditions. These are five-year, milestone-driven awards consisting of two phases. The first two years constitute the UG3 phase and are focused on SenTec development and demonstration of technology feasibility. The following 3-years is the SenTec application UH3 phase where SenTecs continue to be optimized, refined and validated. In the final year of the UH3 award, SenTecs will undertake a demonstration project conducted in a collaborative effort within SenNet to provide further validation of the proposed SenTec. Applicants are required to submit both UG3 and UH3 projects together when responding to this NOFO. Transition from the UG3 to UH3 phases is not automatic and will occur only after administrative review of each SenTec at the close of Year 2 of the award.
Who can apply, from the official notice
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Official notice: https://simpler.grants.gov/opportunity/24e694ee-a9d9-4231-9b02-b4ad438ea211 · Printed from grantme.click/grants/1609541d-e5d0-4213-92f5-0aeb45bbdeb2
View on Grants.gov Add deadline to my calendar
Your schedule, working back from the deadline
- Oct9
Check that your SAM.gov registration is active (or start it now)
Grants.gov: allow up to 10 business days for SAM registration, weeks or months if information isn't verified. It must be renewed every year. Grants.gov - Nov2
Ask partners for letters of support or commitment
Suggested: partners need about three weeks to write and sign letters. - Nov16
Finish a complete draft for a final review
Suggested: leave about a week for someone else to read the draft. - Nov21
Submit
Grants.gov: submit at least 24–48 hours before the deadline: uploads fail, systems slow down, errors need fixing. Grants.gov blog - Nov23
Deadline
From the funder.
Save this grant to put these dates in My grants and your private calendar.
Writing the need statement? Madison County facts with citations.
Who in Tennessee has won this program
29 awards to Tennessee groups in 2 counties since 1996 · 0 in Madison County. Largest shown:
| Past winner | Where | Amount | Fiscal year |
|---|---|---|---|
| Vanderbilt University Medical Center | Nashville, Davidson County | $143.7M | 2016 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $51.7M spent that year | 2025 |
| Meharry Medical College | Nashville, Davidson County | $45.7M | |
| Vanderbilt University Medical Center | Nashville, Davidson County | $32.8M | 2023 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $27.5M | 1997 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $22M | 2016 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $19.6M | 2011 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $12.6M | 2016 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $9.3M | 2021 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $8.5M | 2022 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $8M | 2025 |
| University of Memphis | Memphis, Shelby County | $7.7M | 2020 |
Source: USAspending.gov; Federal Audit Clearinghouse. Past awards show who this program funds. They don't guarantee future awards.
Tennessee groups that got this money through a state agency or another organization
This federal money also reaches local groups as pass-through grants. 53 pass-through grants on file · 0 in Madison County. Largest shown:
| Past winner | Where | Through | Amount | Fiscal year |
|---|---|---|---|---|
| Vanderbilt University Medical Center | Nashville, Davidson County | Yale Univ | $3.4M | 2023 |
| Vanderbilt University | Nashville, Davidson County | Vanderbilt University Medical Center | $2.6M | 2025 |
| Vanderbilt University Medical Center | Nashville, Davidson County | University of Wisconsin System | $2.2M | 2023 |
| Vanderbilt University | Nashville, Davidson County | Vanderbilt University Medical Center | $2M | 2024 |
| Vanderbilt University | Nashville | Vanderbilt University Medical Center | $1.9M spent that year | 2025 |
| Meharry Medical College | Nashville, Davidson County | University of North Texas Health Science Center | $1.4M spent that year | 2025 |
| Vanderbilt University Medical Center | Nashville, Davidson County | University of North Texas Hsc | $1.1M spent that year | 2025 |
| University of Tennessee | Knoxville, Knox County | University of Washington | $945K | 2023 |
| Vanderbilt University Medical Center | Nashville, Davidson County | Yale University | $704K spent that year | 2025 |
| Vanderbilt University Medical Center | Nashville, Davidson County | University of Wisconsin System | $620K | 2023 |
| Meharry Medical College | Nashville, Davidson County | Unthsc | $593K spent that year | 2023 |
| Vanderbilt University | Nashville, Davidson County | Vanderbilt University Medical Center | $582K | 2026 |
Source: USAspending.gov pass-through reports (the first recipient reports each one of $30,000 or more).
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About the federal program
Trans-NIH Research Support, also called “NIH-wide Research Support”
Program number 93.310 (the federal Assistance Listing number) · U.S. Department of Health and Human Services, National Institutes of Health · Project grant, training
How applications are judged
Funding decisions are based on scientific merit (42 CFR 52h) and program relevance. Scientific merit review encompasses: the peer review criteria detailed in the specific funding announcement, as well as the significance, approach, and innovation of the proposed research; the competency of the principal investigator; the adequacy of the resources and environment; the proposed budget and requested period of support; and, where applicable, the adequacy of the measures for protecting against adverse effects upon humans, animals, or the environment.
Match
None required (federal program listing).