National Institutes of Health · Department of Health and Human Services
GREGoRi Innovation Projects (U01 Clinical Trial Optional)
Key facts
- Deadline
- Due Oct 30, 2026 · 23 days left
- Award size
- Up to $500K
- Total available
- $7.5M · about 10 awards
- Match ?
- Not required · Work out your budget and match
- Who can apply
- Private college or university, Small business, Nonprofit without 501(c)(3), State government, Larger business, School district, County government, Special district (utility, fire, etc.), Nonprofit with 501(c)(3), Public college or university, City or town government, Tribal government, Tribal organization, and others named in the official notice
- Where
- Anywhere in the U.S., including Tennessee
Before you apply: federal grants require an active SAM.gov registration (Unique Entity ID) and a Grants.gov account. The deadline is in 23 days. If your registration isn't already active, it may not be ready in time, so check it today. Get-ready checklist
How this fits you
- Available in Warren County (nationwide program)
- No match required
- Past Tennessee awards on file: 45
Tell us who you are to see whether you're eligible.
Official notice: https://simpler.grants.gov/opportunity/4dd61e81-d44e-4e85-a0e2-c422124fd0b9 · Printed from grantme.click/grants/03637c27-49d2-44b3-8b09-103aa78534f8
View on Grants.gov Add deadline to my calendar
More from National Institutes of Health
- Systematic Characterization of Genomic Variation to Assess Effects of Individual Variants on Genome Function and Phenotype (UM1 Clinical Trials Not Allowed) · The funder's estimated date (Jul 15, 2025) has passed. Check the official notice Estimate, not confirmed by the funder
- IGVF Data and Coordinating Center (U24 Clinical trials Not Allowed) · The funder's estimated date (Jul 15, 2025) has passed. Check the official notice Estimate, not confirmed by the funder
- Forecast to Renew the Notice of Funding Opportunity Announcement for the Multiple Chronic Disease Research Centers · The funder's estimated date (Jul 25, 2025) has passed. Check the official notice Estimate, not confirmed by the funder
- Genomic Variant Interactions With Other Variants Or The Environment (UM1 Clinical Trials Not Allowed) · The funder's estimated date (Aug 22, 2025) has passed. Check the official notice Estimate, not confirmed by the funder
- Forecast to Publish a Funding Opportunity Announcement for the Consortium on the Neurobiology of Adolescent Drinking in Adulthood (NADIA) Research Resource (Collaborative U24 - Clinical Trials not allowed) · The funder's estimated date (Sep 30, 2025) has passed. Check the official notice Estimate, not confirmed by the funder
- Forecast to Publish a Funding Opportunity Announcement for the Consortium on the Neurobiology of Adolescent Drinking in Adulthood (NADIA) Administrative Resource (Collaborative U24 - Clinical Trials not allowed) · The funder's estimated date (Sep 30, 2025) has passed. Check the official notice Estimate, not confirmed by the funder
About this grant
The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. This Notice of Funding Opportunity is intended to stimulate the development and testing of highly innovative experimental or computational approaches for rare disease diagnosis, that have the potential to make transformative improvements to the current state of the art.
Who can apply, from the official notice
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Your schedule, working back from the deadline
- Oct7
Check that your SAM.gov registration is active (or start it now)
Grants.gov: allow up to 10 business days for SAM registration, weeks or months if information isn't verified. It must be renewed every year. Grants.gov - Oct9
Ask partners for letters of support or commitment
Suggested: partners need about three weeks to write and sign letters. - Oct23
Finish a complete draft for a final review
Suggested: leave about a week for someone else to read the draft. - Oct28
Submit
Grants.gov: submit at least 24–48 hours before the deadline: uploads fail, systems slow down, errors need fixing. Grants.gov blog - Oct30
Deadline
From the funder.
Save this grant to put these dates in My grants and your private calendar.
Writing the need statement? Warren County facts with citations.
Who in Tennessee has won this program
23 awards to Tennessee groups in 2 counties since 2016 · 0 in Warren County. Largest shown:
| Past winner | Where | Amount | Fiscal year |
|---|---|---|---|
| Vanderbilt University Medical Center | Nashville, Davidson County | $16.8M | 2020 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $8.1M | 2016 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $8M | 2018 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $7M | 2020 |
| St Jude Children's Research Hospital Inc | Memphis, Shelby County | $5.2M | 2018 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $4.6M | 2022 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $4.5M | 2023 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $4.4M | 2024 |
| Vanderbilt University | Nashville, Davidson County | $4.3M | 2016 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $4.3M | 2022 |
| Meharry Medical College | Nashville, Davidson County | $4.2M | 2023 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $3.3M | 2017 |
Source: USAspending.gov. Past awards show who this program funds. They don't guarantee future awards.
Tennessee groups that got this money through a state agency or another organization
This federal money also reaches local groups as pass-through grants. 22 pass-through grants on file · 0 in Warren County. Largest shown:
| Past winner | Where | Through | Amount | Fiscal year |
|---|---|---|---|---|
| Vanderbilt University | Nashville, Davidson County | Vanderbilt University Medical Center | $2.3M | 2023 |
| St Jude Children's Research Hospital Inc | Memphis, Shelby County | Weill Medical College of Cornell University | $2.1M | 2026 |
| Vanderbilt University Medical Center | Nashville, Davidson County | University of Alabama at Birmingham | $1.5M | 2026 |
| Meharry Medical College | Nashville, Davidson County | Vanderbilt University Medical Center | $1.1M | 2023 |
| Vanderbilt University Medical Center | Nashville, Davidson County | University of North Carolina at Chapel Hill | $669K | 2023 |
| Meharry Medical College | Nashville, Davidson County | Vanderbilt University Medical Center | $545K | 2023 |
| Meharry Medical College | Nashville, Davidson County | Vanderbilt University Medical Center | $536K | 2023 |
| St Jude Children's Research Hospital Inc | Memphis, Shelby County | The Leland Stanford Junior University | $444K | 2024 |
| St Jude Children's Research Hospital Inc | Memphis, Shelby County | The Leland Stanford Junior University | $424K | 2026 |
| St Jude Children's Research Hospital Inc | Memphis, Shelby County | The Leland Stanford Junior University | $424K | 2025 |
| Vanderbilt University | Nashville, Davidson County | Vanderbilt University Medical Center | $395K | 2023 |
| Vanderbilt University Medical Center | Nashville, Davidson County | The Broad Institute, Inc | $379K | 2024 |
Source: USAspending.gov pass-through reports (the first recipient reports each one of $30,000 or more).
About the federal program
Human Genome Research, also called “National Human Genome Research Institute”
Program number 93.172 (the federal Assistance Listing number) · U.S. Department of Health and Human Services, National Institutes of Health · Project grant
How applications are judged
In each year's official notice: read this year's.
Match
None required (federal program listing).
Examples of funded projects
Fiscal year 2025: Examples of research supported by NHGRI in FY 2025 include characterization of genes, sequencing, databases, and projects on the following list: https://reporter.nih.gov/search/KP6XtPborUWv7kYNeFlJSA/projects?shared=true
Fiscal year 2026: Current projects supported by NHGRI include basic genomic science; functional and clinical variation; genomic medicine; technology development; computational genomics and data science; training programs; conferences; databases; determining the ethical, legal, and social implications (ELSI) of biomedical and behavioral research; as well as projects on the following list:
https://reporter.nih.gov/search/PbojAWqEZ0aySDrGRZXHTg/projects?shared=true