National Institutes of Health · Department of Health and Human Services
HIV/AIDS Clinical Trials Network Leadership and Operations Centers
In short: A grant from National Institutes of Health. Open to many kinds of groups. See who can apply.
Key facts
- Deadline
- Due about Jan 22, 2027 Estimate, not confirmed by the funder ?
- Award size
- Not stated: see the official notice
- Match ?
- Not required · Work out your budget and match
- Who can apply
- Larger business, Tribal government, State government, School district, Special district (utility, fire, etc.), Small business, Tribal organization, Nonprofit with 501(c)(3), County government, Nonprofit without 501(c)(3), Public college or university, Private college or university, City or town government, and others named in the official notice
- Where
- Anywhere in the U.S., including Tennessee
Opening soon: the funder has announced this grant, but you can't apply yet. Use the time to get ready and check whether it fits.
Before you apply: federal grants require an active SAM.gov registration (Unique Entity ID) and a Grants.gov account. Registration is free but can take weeks, so start now, not when the deadline is close. Get-ready checklist
How this fits you
- Open to: Nonprofit with 501(c)(3)
- Investigator research grant: groups like yours rarely apply
- Available in Rutherford County (nationwide program)
- No match required
- Past Tennessee awards on file: 287
About this grant
The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance the National Institutes of Health (NIH) mission by supporting four Clinical Trials Networks (CTNs) each comprised of a Leadership and Operations Center (LOC), Statistical and Data Management Center, and Laboratory Center working with Clinical Trials Units to advance prevention, treatment, and implementation research designed to end the HIV epidemic. This NOFO will solicit applications for four LOCs to provide scientific leadership, research prioritization, and conduct studies in a CTN. A LOC develops the research agenda in one of these areas: 1) HIV therapeutics/cure, and prevention/treatment for HIV-associated comorbidities in adults; 2) HIV prevention/treatment in maternal/adolescent/pediatric populations; 3) biomedical HIV prevention strategies for adults/adolescents; and 4) immune-based prevention for HIV and HIV-associated diseases. CTNs will conduct HIV implementation research improving uptake of evidence-based prevention and treatment strategies across the lifespan. High impact LOC studies will produce crucial findings significantly benefiting Americans with or at-risk of HIV and HIV-associated diseases.
Grant authorities that allow NIAID to forecast this opportunity are: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
Who can apply, from the official notice
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.
Official notice: https://simpler.grants.gov/opportunity/c28e0695-f517-40da-8653-0cb40f65bc59 · Printed from grantme.click/grants/0090c6cb-a821-4c0f-872f-75832e8b5917
View on Grants.gov Add dates to my calendar
Writing the need statement? Rutherford County facts with citations.
See how others wrote it
The agency posted this example. Read them for structure and level of detail. Don't copy their words: funders treat copied text as plagiarism, and requirements change from year to year, so follow the current notice.
- NIH research, career, fellowship and small-business grants (R01, R03, R15, R21, R21/R33, R41-R44, K01, K08, K23, F31, G11, U01)
Funded applications with reviewer comments
46 full funded applications and 49 reviewer summary statements (PDF), plus sample forms and letters · Link checked Oct 7, 2026
Who in Tennessee has won this program
44 awards to Tennessee groups in 2 counties since 1996 · 0 in Rutherford County. Largest shown:
| Past winner | Where | Amount | Fiscal year |
|---|---|---|---|
| Vanderbilt University Medical Center | Nashville, Davidson County | $143.7M | 2016 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $118.6M | 2017 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $63.8M spent that year | 2025 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $51.7M spent that year | 2025 |
| St Jude Children's Research Hospital Inc | Memphis, Shelby County | $43.7M | 2019 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $43M | 2020 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $38.1M | 2024 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $33.3M | 2011 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $32.8M | 2007 |
| University of Tennessee | Memphis, Shelby County | $21.8M | 2019 |
| St. Jude Children's Research Hospital, Inc. | Memphis, Shelby County | $19.3M spent that year | 2025 |
| State of Tennessee | Nashville | $15.1M spent that year | 2025 |
Source: USAspending.gov; Federal Audit Clearinghouse. Past awards show who this program funds. They don't guarantee future awards.
Tennessee groups that got this money through a state agency or another organization
This federal money also reaches local groups as pass-through grants. 243 pass-through grants on file · 0 in Rutherford County. Largest shown:
| Past winner | Where | Through | Amount | Fiscal year |
|---|---|---|---|---|
| Vanderbilt University Medical Center | Nashville, Davidson County | Yale Univ | $3.4M | 2023 |
| Meharry Medical College | Nashville, Davidson County | Vanderbilt University Medical Center | $2.8M | 2023 |
| Vanderbilt University Medical Center | Nashville, Davidson County | Washington University, the | $2.8M | 2025 |
| Vanderbilt University | Nashville, Davidson County | Vanderbilt University Medical Center | $2.6M | 2025 |
| Vanderbilt University Medical Center | Nashville, Davidson County | University of Wisconsin System | $2.2M | 2023 |
| Vanderbilt University Medical Center | Nashville, Davidson County | Washington University | $2.1M spent that year | 2025 |
| Vanderbilt University | Nashville, Davidson County | Vanderbilt University Medical Center | $2M | 2024 |
| Vanderbilt University Medical Center | Nashville, Davidson County | The Johns Hopkins University | $2M | 2026 |
| Vanderbilt University Medical Center | Nashville, Davidson County | University of Texas Medical Branch at Galveston | $2M spent that year | 2025 |
| Vanderbilt University | Nashville | Vumc | $1.9M spent that year | 2024 |
| Vanderbilt University | Nashville | Vanderbilt University Medical Center | $1.9M spent that year | 2025 |
| Vanderbilt University | Nashville | Vanderbilt University Medical Center | $1.8M spent that year | 2025 |
Source: USAspending.gov pass-through reports (the first recipient reports each one of $30,000 or more).
Similar grants open or opening soon
From other funders, about the same kind of work, for nonprofit with 501(c)(3) in Rutherford County.
- Ryan White HIV/AIDS Program Part D - Women, Infants, Children and Youth Grant Supplemental Funding · Health Resources and Services Administration · Opens Dec 4, 2026 · due about Feb 2, 2027 Estimate, not confirmed by the funder
- Ryan White HIV/AIDS Program Part C Capacity Development Program · Health Resources and Services Administration · Opens Jan 15, 2027 · due about Mar 16, 2027 Estimate, not confirmed by the funder
- Ryan White HIV/AIDS Program (RWHAP) Integrated HIV/AIDS Planning Resource Allocation Cooperative Agreement · Health Resources and Services Administration · Opens Oct 19, 2026 · due about Jan 18, 2027 Estimate, not confirmed by the funder
- Ryan White HIV/AIDS Program Part B AIDS Drug Assistance Program Training and Technical Assistance · Health Resources and Services Administration · Opens Nov 21, 2026 · due about Jan 20, 2027 Estimate, not confirmed by the funder
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About the federal program
Trans-NIH Research Support, also called “NIH-wide Research Support”
Program number 93.310 (the federal Assistance Listing number) · U.S. Department of Health and Human Services, National Institutes of Health · Project grant, training
How applications are judged
Funding decisions are based on scientific merit (42 CFR 52h) and program relevance. Scientific merit review encompasses: the peer review criteria detailed in the specific funding announcement, as well as the significance, approach, and innovation of the proposed research; the competency of the principal investigator; the adequacy of the resources and environment; the proposed budget and requested period of support; and, where applicable, the adequacy of the measures for protecting against adverse effects upon humans, animals, or the environment.
Match
None required (federal program listing).
About the federal program
Allergy and Infectious Diseases Research, also called “National Institutes of Allergy and Infectious Diseases”
Program number 93.855 (the federal Assistance Listing number) · U.S. Department of Health and Human Services, National Institutes of Health · Project grant
How applications are judged
The major elements in evaluating proposals include assessments of: (1) The scientific merit and general significance of the proposed study and its objectives; (2) the technical adequacy of the experimental design and approach; (3) the competency of the proposed investigator or group to successfully pursue the project; (4) the adequacy of the available and proposed facilities and resources; (5) the necessity of the budget components requested in relation to the proposed project; and (6) the relevance and importance to announced program objectives. The following criteria will be used in considering the scientific and technical merit of SBIR/STTR Phase I grant applications: (1) The soundness and technical merit of the proposed approach; (2) the qualifications of the proposed principal investigator, supporting staff, and consultants; (3) the technological innovation of the proposed research; (4) the potential of the proposed research for commercial application; (5) the appropriateness of the budget requested; (6) the adequacy and suitability of the facilities and research environment; and (7) where applicable, the adequacy of assurances detailing the proposed means for (a) safeguarding human or animal subjects, and/or (b) protecting against or minimizing any adverse effect on the environment. Phase II grant applications will be reviewed based upon the following criteria: (1) The degree to which the Phase I objectives were met and feasibility demonstrated; (2) the scientific...
Match
None required (federal program listing).