National Institutes of Health · Department of Health and Human Services
Addressing Methodological Challenges with Clinical Trials of Rapid-Acting Psychotropic Interventional Drugs (RAPIDs) (R01 Clinical Trial Required)
Key facts
- Deadline
- Due Oct 11, 2026 · 4 days left
- Award size
- Not specified — see notice
- Total available
- $5.5M · about 5 awards
- Cost share / match ?
- Not required · Work out your budget and match
- Who can apply
- State government, City or town government, Small business, Tribal government, Other (see eligibility), Private college or university, Larger business, Public college or university, School district, Special district (utility, fire, etc.), County government, Nonprofit without 501(c)(3), Nonprofit with 501(c)(3), Tribal organization
- Where
- Anywhere in the U.S., including Tennessee
Before you apply: federal grants require an active SAM.gov registration (Unique Entity ID) and a Grants.gov account. The deadline is in 4 days. If your registration isn't already active, it may not be ready in time, so check it today. Grant-ready checklist
How this fits you
- Available in Rhea County (nationwide program)
- No cost share required
- Only 4 days left to apply
- Past Tennessee awards on file: 72
Tell us who you are to see whether you're eligible.
More from National Institutes of Health
- Systematic Characterization of Genomic Variation to Assess Effects of Individual Variants on Genome Function and Phenotype (UM1 Clinical Trials Not Allowed) · The funder's estimated date (Jul 15, 2025) has passed. Check the official notice
- IGVF Data and Coordinating Center (U24 Clinical trials Not Allowed) · The funder's estimated date (Jul 15, 2025) has passed. Check the official notice
- Forecast to Renew the Notice of Funding Opportunity Announcement for the Multiple Chronic Disease Research Centers · The funder's estimated date (Jul 25, 2025) has passed. Check the official notice
- Genomic Variant Interactions With Other Variants Or The Environment (UM1 Clinical Trials Not Allowed) · The funder's estimated date (Aug 22, 2025) has passed. Check the official notice
- Forecast to Publish a Funding Opportunity Announcement for the Consortium on the Neurobiology of Adolescent Drinking in Adulthood (NADIA) Administrative Resource (Collaborative U24 - Clinical Trials not allowed) · The funder's estimated date (Sep 30, 2025) has passed. Check the official notice
- Forecast to Publish a Funding Opportunity Announcement for the Consortium on the Neurobiology of Adolescent Drinking in Adulthood (NADIA) Research Resource (Collaborative U24 - Clinical Trials not allowed) · The funder's estimated date (Sep 30, 2025) has passed. Check the official notice
Official notice: https://simpler.grants.gov/opportunity/50a28cda-9dcb-4999-bc2c-75ad4e7cc547 · Printed from grantme.click/grants/c9ab59a0-719b-4887-95bf-f22f4ffab2fd
Read the official notice View on Grants.gov Add deadline to my calendar Sign in to save
About this grant
The purpose of this notice of funding opportunity (NOFO) is to elucidate the key components of the therapeutic effects of rapid-acting psychotropic interventional drugs (RAPIDs) by addressing the methodological challenges involved with these clinical trials. In addition, this NOFO seeks to advance understanding of how RAPIDs and adjunctive psychosocial interventions can be optimally delivered, monitored, and sustained over time to enhance effectiveness and generalizability. The NOFO will support studies designed to enhance the rigor of RAPID clinical trial design, which will ultimately increase the interpretability of the data and the generalizability of the results.
Eligibility (from the notice)
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Should we apply? (2-minute check) Ask a partner for a letter
Your schedule, working back from the deadline
- Oct7
Check that your SAM.gov registration is active (or start it now)
Grants.gov: allow up to 10 business days for SAM registration, weeks or months if information isn't verified. It must be renewed every year. Grants.gov - Sep20
Ask partners for letters of support or commitment (already past: do it now)
Suggested: partners need about three weeks to write and sign letters. - Oct5
Finish a complete draft for a final review (already past: do it now)
Suggested: leave about a week for someone else to read the draft. - Oct9
Submit
Grants.gov: submit at least 24–48 hours before the deadline: uploads fail, systems slow down, errors need fixing. Grants.gov blog - Oct11
Deadline
From the funder.
Save this grant to put these dates in your tracker and private calendar.
Writing the need statement? Rhea County facts with citations.
Who in Tennessee has won this program
41 awards to Tennessee recipients in 4 counties since 1989 · 0 in Rhea County. Largest shown:
| Recipient | Where | Amount | FY |
|---|---|---|---|
| Vanderbilt University | Nashville, Davidson County | $8.7M | 2001 |
| Vanderbilt University | Nashville, Davidson County | $8.7M | 2006 |
| Vanderbilt University | Nashville, Davidson County | $8.1M | 2005 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $7.4M | 2020 |
| Vanderbilt University | Nashville, Davidson County | $6.8M | 2004 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $6.4M | 2005 |
| Vanderbilt University | Nashville, Davidson County | $5.4M | 2009 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $5.3M | 2020 |
| Vanderbilt University | Nashville, Davidson County | $5M | 2002 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $4.5M | 2016 |
| Vanderbilt University | Nashville, Davidson County | $4.5M | 1989 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $4.4M | 2023 |
Source: USAspending.gov. Past awards show who this program funds; they don't guarantee future awards.
Tennessee groups that got this money through a state agency or another grantee
This federal money also reaches local groups as subawards. 31 subawards on file · 0 in Rhea County. Largest shown:
| Recipient | Where | Through | Amount | FY |
|---|---|---|---|---|
| Vanderbilt University Medical Center | Nashville, Davidson County | The Trustees of Princeton University | $1.6M | 2023 |
| Vanderbilt University | Nashville, Davidson County | The Pennsylvania State University | $1.1M | 2026 |
| Vanderbilt University Medical Center | Nashville, Davidson County | The General Hospital Corporation | $839K | 2026 |
| Vanderbilt University | Nashville, Davidson County | The Pennsylvania State University | $756K | 2025 |
| Vanderbilt University Medical Center | Nashville, Davidson County | Icahn School of Medicine At Mount Sinai | $734K | 2025 |
| Vanderbilt University | Nashville, Davidson County | Vanderbilt University Medical Center | $560K | 2023 |
| University Of Tennessee | Memphis, Shelby County | University of Puerto Rico | $553K | 2026 |
| Vanderbilt University Medical Center | Nashville, Davidson County | Icahn School of Medicine At Mount Sinai | $462K | 2024 |
| Vanderbilt University Medical Center | Nashville, Davidson County | Vanderbilt University | $385K | 2023 |
| Ut-Battelle Llc | Oak Ridge, Anderson County | Research Triangle Institute | $368K | 2023 |
| St Jude Children'S Research Hospital Inc | Memphis, Shelby County | University of Kentucky Research Foundation, the | $361K | 2023 |
| Vanderbilt University Medical Center | Nashville, Davidson County | Vanderbilt University | $359K | 2024 |
Source: USAspending.gov subaward reports (prime recipients report subawards of $30,000 or more).
About the program (93.242)
Mental Health Research Grants
How applications are judged
The following consideration will be used in determining projects to be funded: (1) Technical merit of the proposed project as determined by peer review; (2) Availability of funds; and (3) Relevance to program priorities.
Matching requirements
This program has no statutory formula.
Matching requirements are not applicable to this assistance listing.
MOE requirements are not applicable to this assistance listing.
Examples of funded projects
Not Applicable.
About the program (93.279)
Drug Use and Addiction Research Programs
How applications are judged
The following considerations will be used in determining projects to be funded: (1) Scientific and technical merit; (2) the feasibility of the research; (3) potential contribution to the national drug abuse problem; and (4) relevance to NIDA priorities. The following criteria will be used in considering the scientific and technical merit of SBIR/STTR Phase I grant applications: (1) The soundness and technical merit of the proposed approach; (2) the qualifications of the proposed principal investigator, supporting staff, and consultants; (3) the technological innovation of the proposed research; (4) the potential of the proposed research for commercial application; (5) the appropriateness of the budget requested; (6) the adequacy and suitability of the facilities and research environment; and (7) where applicable, the adequacy of assurances detailing the proposed means for (a) safeguarding human or animal subjects and/or (b) protecting against or minimizing any adverse effect on the environment. Phase II grant applications will be reviewed based upon the following criteria: (1) The degree to which the Phase I objectives were met and feasibility demonstrated; (2) the scientific and technical merit of the proposed approach for achieving the Phase II objectives; (3) the qualifications of the proposed principal investigator, supporting staff, and consultants; (4) the technology.
Matching requirements
This program has no statutory formula.
Matching requirements are not applicable to this assistance listing.
MOE requirements are not applicable to this assistance listing.
Examples of funded projects
Not Applicable.