← Back to search

National Institutes of Health · Department of Health and Human Services

Mood and Psychosis Symptoms during the Menopause Transition (R01 Clinical Trial Optional)

Open · Opportunity PAR-25-281 · Assistance Listing 93.242, 93.313

Key facts

Deadline
Due Jan 7, 2028 · 457 days left
Award size
Not specified — see notice
Cost share / match ?
Not required · Work out your budget and match
Who can apply
Special district (utility, fire, etc.), Other (see eligibility), Nonprofit with 501(c)(3), Tribal organization, State government, School district, Public college or university, Private college or university, Tribal government, Small business, Larger business, County government, Nonprofit without 501(c)(3), City or town government
Where
Anywhere in the U.S., including Tennessee

Before you apply: federal grants require an active SAM.gov registration (Unique Entity ID) and a Grants.gov account. Registration is free but can take weeks, so start now, not when the deadline is close. Grant-ready checklist

How this fits you

  • Available in Tennessee (nationwide program)
  • No cost share required
  • Tennessee recipients since 2023: 43

Tell us who you are to see whether you're eligible.

More from National Institutes of Health

Read the official notice View on Grants.gov Add deadline to my calendar Sign in to save

About this grant

The purpose of this Notice of Funding Opportunity (NOFO) is to advance translational research to better understand the emergence and worsening of mood and psychotic disorders (e.g., perimenopausal depression (PMD), generalized anxiety disorder, bipolar disorder and schizophrenia) during the menopause transition (MT) in an effort to identity targets for future development of novel treatment interventions. This funding opportunity aims to advance novel and innovative translational research to better comprehend the underlying neurobiological and behavioral mechanisms of mood and psychosis disorders and related symptoms during MT. This funding opportunity also encourages interdisciplinary researchers to collaborate on studies of mood and psychosis during the MT. Aspects of mood and psychosis disorders that are of interest include: classic depressive symptoms in combination with menopause symptoms (e.g., hot flashes, night sweats, sleep disturbance) and psychological challenges, the role of reproductive steroids in the regulation of mood and behavior during the MT, diagnosis of mood and psychosis symptoms at menopausal stage, investigation of co-occurring psychiatric and menopause symptoms, appreciation of psychosocial factors common in midlife, and differential diagnoses. Review criteria will focus on the comprehensiveness of the neurobiology and mechanisms of action underlying mood and psychosis symptoms and hypothesis-driven work.

Eligibility (from the notice)

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Should we apply? (2-minute check) Ask a partner for a letter

Your schedule, working back from the deadline

  1. Oct7
    Check that your SAM.gov registration is active (or start it now)
    Grants.gov: allow up to 10 business days for SAM registration, weeks or months if information isn't verified. It must be renewed every year. Grants.gov
  2. Dec17
    Ask partners for letters of support or commitment
    Suggested: partners need time to write and sign letters.
  3. Dec31
    Finish a complete draft for a final review
    University grant offices require final versions about 5 business days before the sponsor deadline. Emory Office of Sponsored Programs
  4. Jan5
    Submit
    Grants.gov: submit at least 24–48 hours before the deadline: uploads fail, systems slow down, errors need fixing. Grants.gov blog
  5. Jan7
    Deadline
    From the funder.

Save this grant to put these dates in your tracker and private calendar.

Who in Tennessee has won this program

22 awards to Tennessee recipients in 2 counties since federal FY2023. Largest shown:

Past Tennessee recipients
RecipientWhereAmountFY
Vanderbilt UniversityNashville, Davidson County$8.7M2001
Vanderbilt UniversityNashville, Davidson County$8.7M2006
Vanderbilt UniversityNashville, Davidson County$8.1M2005
Vanderbilt University Medical CenterNashville, Davidson County$7.4M2020
Vanderbilt UniversityNashville, Davidson County$6.8M2004
Vanderbilt University Medical CenterNashville, Davidson County$6.4M2005
Vanderbilt UniversityNashville, Davidson County$5.4M2009
Vanderbilt University Medical CenterNashville, Davidson County$5.3M2020
Vanderbilt UniversityNashville, Davidson County$5M2002
Vanderbilt UniversityNashville, Davidson County$4.5M1989
Vanderbilt University Medical CenterNashville, Davidson County$4.3M2019
Vanderbilt University Medical CenterNashville, Davidson County$4.1M2014

Source: USAspending.gov. Past awards show who this program funds; they don't guarantee future awards.

Tennessee groups that got this money through a state agency or another grantee

This federal money also reaches local groups as subawards. 21 subawards on file. Largest shown:

Tennessee subaward recipients
RecipientWhereThroughAmountFY
Vanderbilt University Medical CenterNashville, Davidson CountyThe Trustees of Princeton University$1.6M2023
Vanderbilt UniversityNashville, Davidson CountyThe Pennsylvania State University$1.1M2026
Vanderbilt University Medical CenterNashville, Davidson CountyThe General Hospital Corporation$839K2026
Vanderbilt UniversityNashville, Davidson CountyThe Pennsylvania State University$756K2025
Vanderbilt University Medical CenterNashville, Davidson CountyIcahn School of Medicine At Mount Sinai$734K2025
Vanderbilt UniversityNashville, Davidson CountyVanderbilt University Medical Center$560K2023
University Of TennesseeMemphis, Shelby CountyUniversity of Puerto Rico$553K2026
Vanderbilt University Medical CenterNashville, Davidson CountyIcahn School of Medicine At Mount Sinai$462K2024
Vanderbilt University Medical CenterNashville, Davidson CountyVanderbilt University$385K2023
Vanderbilt University Medical CenterNashville, Davidson CountyVanderbilt University$359K2024
Vanderbilt UniversityNashville, Davidson CountyThe Trustees of Columbia University in the City of New York$346K2025
Vanderbilt University Medical CenterNashville, Davidson CountyVanderbilt University$339K2026

Source: USAspending.gov subaward reports (prime recipients report subawards of $30,000 or more).

About the program (93.242)

Mental Health Research Grants

How applications are judged

The following consideration will be used in determining projects to be funded: (1) Technical merit of the proposed project as determined by peer review; (2) Availability of funds; and (3) Relevance to program priorities.

Matching requirements

This program has no statutory formula. Matching requirements are not applicable to this assistance listing. MOE requirements are not applicable to this assistance listing.

Examples of funded projects

Not Applicable.

Program listing on SAM.gov

About the program (93.313)

NIH Office of Research on Women's Health — (NIH/ORWH)

How applications are judged

Submitted proposals are accepted for review and possible funding based on the eligibility Information specified in the NOFO.

Matching requirements

This program has no statutory formula. Matching requirements are not applicable to this assistance listing. MOE requirements are not applicable to this assistance listing.

Examples of funded projects

Not Applicable.

Program listing on SAM.gov

Something wrong with this listing? Tell us
What's wrong?