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National Institutes of Health · Department of Health and Human Services

GREGoRi Technology Integration Center (U01, Clinical Trials Optional)

Open · Opportunity RFA-HG-27-012 · Assistance Listing 93.172

Key facts

Deadline
Due Oct 30, 2026 · 23 days left
Award size
Up to $2.2M
Total available
$3M · about 1 award
Cost share / match ?
Not required · Work out your budget and match
Who can apply
County government, Other (see eligibility), Tribal organization, Larger business, City or town government, Special district (utility, fire, etc.), School district, Nonprofit with 501(c)(3), Small business, Tribal government, Nonprofit without 501(c)(3), Public college or university, State government, Private college or university
Where
Anywhere in the U.S., including Tennessee

Before you apply: federal grants require an active SAM.gov registration (Unique Entity ID) and a Grants.gov account. The deadline is in 23 days. If your registration isn't already active, it may not be ready in time, so check it today. Grant-ready checklist

How this fits you

  • Available in Tennessee (nationwide program)
  • No cost share required
  • Past Tennessee awards on file: 45

Tell us who you are to see whether you're eligible.

More from National Institutes of Health

Read the official notice View on Grants.gov Add deadline to my calendar Sign in to save

About this grant

The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this Notice of Funding Opportunity is to establish the GREGoRi Technology Integration Center, which will enable the development of standards and best practices for applying new and emerging molecular methods in rare disease diagnosis. A major deliverable of the Center will be a multidimensional dataset that can be used for the development and benchmarking of novel tools and strategies that facilitate rare disease diagnosis.

Eligibility (from the notice)

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Should we apply? (2-minute check) Ask a partner for a letter

Your schedule, working back from the deadline

  1. Oct7
    Check that your SAM.gov registration is active (or start it now)
    Grants.gov: allow up to 10 business days for SAM registration, weeks or months if information isn't verified. It must be renewed every year. Grants.gov
  2. Oct9
    Ask partners for letters of support or commitment
    Suggested: partners need time to write and sign letters.
  3. Oct23
    Finish a complete draft for a final review
    University grant offices require final versions about 5 business days before the sponsor deadline. Emory Office of Sponsored Programs
  4. Oct28
    Submit
    Grants.gov: submit at least 24–48 hours before the deadline: uploads fail, systems slow down, errors need fixing. Grants.gov blog
  5. Oct30
    Deadline
    From the funder.

Save this grant to put these dates in your tracker and private calendar.

Who in Tennessee has won this program

23 awards to Tennessee recipients in 2 counties since 2016. Largest shown:

Past Tennessee recipients
RecipientWhereAmountFY
Vanderbilt University Medical CenterNashville, Davidson County$16.8M2020
Vanderbilt University Medical CenterNashville, Davidson County$8.1M2016
Vanderbilt University Medical CenterNashville, Davidson County$8M2018
Vanderbilt University Medical CenterNashville, Davidson County$7M2020
St Jude Children'S Research Hospital IncMemphis, Shelby County$5.2M2018
Vanderbilt University Medical CenterNashville, Davidson County$4.6M2022
Vanderbilt University Medical CenterNashville, Davidson County$4.5M2023
Vanderbilt University Medical CenterNashville, Davidson County$4.4M2024
Vanderbilt UniversityNashville, Davidson County$4.3M2016
Vanderbilt University Medical CenterNashville, Davidson County$4.3M2022
Meharry Medical CollegeNashville, Davidson County$4.2M2023
Vanderbilt University Medical CenterNashville, Davidson County$3.3M2017

Source: USAspending.gov. Past awards show who this program funds; they don't guarantee future awards.

Tennessee groups that got this money through a state agency or another grantee

This federal money also reaches local groups as subawards. 22 subawards on file. Largest shown:

Tennessee subaward recipients
RecipientWhereThroughAmountFY
Vanderbilt UniversityNashville, Davidson CountyVanderbilt University Medical Center$2.3M2023
St Jude Children'S Research Hospital IncMemphis, Shelby CountyWeill Medical College of Cornell University$2.1M2026
Vanderbilt University Medical CenterNashville, Davidson CountyUniversity of Alabama At Birmingham$1.5M2026
Meharry Medical CollegeNashville, Davidson CountyVanderbilt University Medical Center$1.1M2023
Vanderbilt University Medical CenterNashville, Davidson CountyUniversity of North Carolina At Chapel Hill$669K2023
Meharry Medical CollegeNashville, Davidson CountyVanderbilt University Medical Center$545K2023
Meharry Medical CollegeNashville, Davidson CountyVanderbilt University Medical Center$536K2023
St Jude Children'S Research Hospital IncMemphis, Shelby CountyThe Leland Stanford Junior University$444K2024
St Jude Children'S Research Hospital IncMemphis, Shelby CountyThe Leland Stanford Junior University$424K2026
St Jude Children'S Research Hospital IncMemphis, Shelby CountyThe Leland Stanford Junior University$424K2025
Vanderbilt UniversityNashville, Davidson CountyVanderbilt University Medical Center$395K2023
Vanderbilt University Medical CenterNashville, Davidson CountyThe Broad Institute, Inc$379K2024

Source: USAspending.gov subaward reports (prime recipients report subawards of $30,000 or more).

About the program (93.172)

Human Genome Research — National Human Genome Research Institute

How applications are judged

Criteria for selecting proposals is described at the NOFO level.

Matching requirements

This program has no statutory formula. Matching requirements are not applicable to this assistance listing. MOE requirements are not applicable to this assistance listing.

Examples of funded projects

Fiscal Year2025: Examples of research supported by NHGRI in FY 2025 include characterization of genes, sequencing, databases, and projects on the following list: https://reporter.nih.gov/search/KP6XtPborUWv7kYNeFlJSA/projects?shared=trueFiscal Year2026: Current projects supported by NHGRI include basic genomic science; functional and clinical variation; genomic medicine; technology development; computational genomics and data science; training programs; conferences; databases; determining the ethical, legal, and social implications (ELSI) of biomedical and behavioral research; as well as projects on the following list: https://reporter.nih.gov/search/PbojAWqEZ0aySDrGRZXHTg/projects?shared=true

Program listing on SAM.gov

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