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National Institutes of Health · Department of Health and Human Services

Developing novel theory and methods for understanding the genetic architecture of complex human traits (R01 Clinical Trial Not Allowed)

Open · Opportunity PAR-25-255 · Assistance Listing 93.399, 93.172, 93.242

Key facts

Deadline
Due Nov 5, 2026 · 30 days left
Award size
Not specified — see notice
Cost share / match
Not required
Who can apply
Nonprofit without 501(c)(3), Tribal government, Other (see eligibility), Public college or university, Private college or university, Special district (utility, fire, etc.), City or town government, County government, Larger business, Tribal organization, Small business, State government, School district, Nonprofit with 501(c)(3)
Where
Anywhere in the U.S., including Tennessee

How this fits you

  • Available in Tennessee (nationwide program)
  • No cost share required
  • Tennessee recipients since 2023: 47

Tell us who you are to see whether you're eligible.

Read the official notice View on Grants.gov

About this grant

The goal of this NOFO is to support applications for novel theory and methods development that enable better understanding of how genetic and non-genetic factors contribute to complex trait variation across individuals, families, and populations. Approaches should be interdisciplinary drawing from the natural and social sciences, account for interdependencies across scales of biological, social, and ecological organization, and make extensive use of theory, modeling, and validation with available large-scale datasets.

Eligibility (from the notice)

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Who in Tennessee has won this program

47 awards to Tennessee recipients in 3 counties since federal FY2023. Largest shown:

Past Tennessee recipients
RecipientWhereAmountFY
Vanderbilt University Medical CenterNashville, Davidson County$16.8M2020
Baptist Memorial Hospital-TiptonCovington, Tipton County$11.9M2014
Vanderbilt UniversityNashville, Davidson County$8.7M2001
Vanderbilt UniversityNashville, Davidson County$8.7M2006
Vanderbilt University Medical CenterNashville, Davidson County$8.1M2016
Vanderbilt UniversityNashville, Davidson County$8.1M2005
Vanderbilt University Medical CenterNashville, Davidson County$8M2018
Vanderbilt University Medical CenterNashville, Davidson County$7.4M2020
Vanderbilt University Medical CenterNashville, Davidson County$7M2020
St Jude Children'S Research Hospital IncMemphis, Shelby County$6.8M2005
Vanderbilt UniversityNashville, Davidson County$6.8M2004
Vanderbilt University Medical CenterNashville, Davidson County$6.4M2005

Source: USAspending.gov. Past awards show who this program funds; they don't guarantee future awards.

About the program (93.172)

Human Genome Research — National Human Genome Research Institute

How applications are judged

Criteria for selecting proposals is described at the NOFO level.

Matching requirements

This program has no statutory formula. Matching requirements are not applicable to this assistance listing. MOE requirements are not applicable to this assistance listing.

Examples of funded projects

Fiscal Year2025: Examples of research supported by NHGRI in FY 2025 include characterization of genes, sequencing, databases, and projects on the following list: https://reporter.nih.gov/search/KP6XtPborUWv7kYNeFlJSA/projects?shared=trueFiscal Year2026: Current projects supported by NHGRI include basic genomic science; functional and clinical variation; genomic medicine; technology development; computational genomics and data science; training programs; conferences; databases; determining the ethical, legal, and social implications (ELSI) of biomedical and behavioral research; as well as projects on the following list: https://reporter.nih.gov/search/PbojAWqEZ0aySDrGRZXHTg/projects?shared=true

Program listing on SAM.gov

About the program (93.242)

Mental Health Research Grants

How applications are judged

The following consideration will be used in determining projects to be funded: (1) Technical merit of the proposed project as determined by peer review; (2) Availability of funds; and (3) Relevance to program priorities.

Matching requirements

This program has no statutory formula. Matching requirements are not applicable to this assistance listing. MOE requirements are not applicable to this assistance listing.

Examples of funded projects

Not Applicable.

Program listing on SAM.gov

About the program (93.399)

Cancer Control — Cancer Control Grants

How applications are judged

The major elements in evaluating proposals include assessments of: (1) The scientific merit and general significance of the proposed study and its objectives; (2) the technical adequacy of the experimental design and approach; (3) the competency of the proposed investigator or group to successfully pursue the project; (4) the adequacy of the available and proposed facilities and resources; (5) the necessity of the budget components requested in relation to the proposed project; and (6) the relevance and importance to announced program objectives.

Matching requirements

This program has no statutory formula. Matching requirements are not applicable to this assistance listing. MOE requirements are not applicable to this assistance listing.

Examples of funded projects

Not Applicable.

Program listing on SAM.gov

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