Martin Delaney Collaboratories for HIV Cure Research

The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance its mission by continuing support for the Martin Delaney Collaboratories (MDCs) for HIV Cure Research. The goal of the MDC program is to develop strategies to control viral replication without the need for lifelong antiretroviral therapy, with an ultimate goal of completely eradicating HIV reservoirs from the individual. The program will also address the unique needs of children living with HIV. The MDC program will accelerate HIV cure research by fostering strategic collaborations among academic institutions, scientists in government, the private sector, and community stakeholders. The program provides economies of scale by leveraging shared reagents, research resources, and specialized technologies in support of basic, translational, and clinical research. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.

The major elements in evaluating proposals include assessments of: (1) The scientific merit and general significance of the proposed study and its objectives; (2) the technical adequacy of the experimental design and approach; (3) the competency of the proposed investigator or group to successfully pursue the project; (4) the adequacy of the available and proposed facilities and resources; (5) the necessity of the budget components requested in relation to the proposed project; and (6) the relevance and importance to announced program objectives. The following criteria will be used in considering the scientific and technical merit of SBIR/STTR Phase I grant applications: (1) The soundness and technical merit of the proposed approach; (2) the qualifications of the proposed principal investigator, supporting staff, and consultants; (3) the technological innovation of the proposed research; (4) the potential of the proposed research for commercial application; (5) the appropriateness of the budget requested; (6) the adequacy and suitability of the facilities and research environment; and (7) where applicable, the adequacy of assurances detailing the proposed means for (a) safeguarding human or animal subjects, and/or (b) protecting against or minimizing any adverse effect on the environment. Phase II grant applications will be reviewed based upon the following criteria: (1) The degree to which the Phase I objectives were met and feasibility demonstrated; (2) the...

This program has no statutory formula. Matching requirements are not applicable to this assistance listing. MOE requirements are not applicable to this assistance listing.

Not Applicable.