National Institutes of Health · Department of Health and Human Services
CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Basic Research on Chemical Threats that Affect the Nervous System (R01 Clinical Trial Not Allowed)
Open
· Opportunity PAR-25-077
· Assistance Listing 93.855, 93.853
Key facts
- Deadline
- Due Oct 16, 2026 · 10 days left
- Award size
- Up to $300K
- Total available
- $300K · about 4 awards
- Cost share / match
- Not required
- Who can apply
- Special district (utility, fire, etc.), Nonprofit with 501(c)(3), City or town government, Other (see eligibility), Nonprofit without 501(c)(3), County government, Larger business, Public college or university, State government, Small business, Private college or university, School district, Tribal government, Tribal organization
- Where
- Anywhere in the U.S., including Tennessee
Before you apply: federal grants require an active SAM.gov registration (Unique Entity ID) and a Grants.gov account.
The deadline is in 10 days. If your registration isn't already active, it may not be ready in time, so check it today.
Grant-ready checklist
How this fits you
- ✓ Available in Tennessee (nationwide program)
- ✓ No cost share required
- ! Only 10 days left to apply
- i Tennessee recipients since 2023: 38
Tell us who you are to see whether you're eligible.
Read the official notice
View on Grants.gov
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About this grant
This announcement invites applications for basic research projects on chemical warfare agents, toxic industrial chemicals, and pesticides that have primary or secondary effects on the nervous system. Chemical threats are toxic compounds that could be used in a terrorist attack or accidentally released from industrial production, storage, or shipping. Projects supported by this NOFO are expected to generate data that elucidate mechanisms of toxicity of these agents, possible new manifestations of toxic exposures, and potential new targets for therapeutic development.
Eligibility (from the notice)
Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.
Who in Tennessee has won this program
38 awards to Tennessee recipients in 2 counties since federal FY2023. Largest shown:
Past Tennessee recipients
| Recipient | Where | Amount | FY |
| St Jude Children'S Research Hospital Inc | Memphis, Shelby County | $43.7M | 2019 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $43M | 2020 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $38.1M | 2024 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $33.3M | 2011 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $32.8M | 2007 |
| University Of Tennessee | Memphis, Shelby County | $21.8M | 2019 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $13.2M | 2020 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $12.3M | 2008 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $12M | 2015 |
| University Of Tennessee | Memphis, Shelby County | $9.5M | 2023 |
| St Jude Children'S Research Hospital Inc | Memphis, Shelby County | $8.9M | 2010 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $8.6M | 2021 |
Source: USAspending.gov. Past awards show who this program funds; they don't guarantee future awards.
About the program (93.853)
Extramural Research Programs in the Neurosciences and Neurological Disorders
How applications are judged
The major elements in evaluating proposals include assessments of: (1) the scientific merit and general significance of the proposed study and its objectives; (2) the technical adequacy of the experimental design and approach; (3) the competency of the proposed investigator or group to successfully pursue the project; (4) the adequacy of the available and proposed facilities and resources; (5) the necessity of the budget components requested in relation to the proposed project; and (6) the relevance and importance to announced program objectives. The following criteria will be used in considering the scientific and technical merit of SBIR/STTR Phase I grant applications: (1) the soundness and technical merit of the proposed approach; (2) the qualifications of the proposed principal investigator, supporting staff, and consultants; (3) the technological innovation of the proposed research; (4) the potential of the proposed research for commercial application; (5) the appropriateness of the budget requested; (6) the adequacy and suitability of the facilities and research environment; and (7) where applicable, the adequacy of assurances detailing the proposed means for (a) safeguarding human or animal subjects, and/or (b) protecting against or minimizing any adverse effect on the environment. Phase II grant applications will be reviewed based upon the following criteria: (1) the degree to which the Phase I objectives were met and feasibility demonstrated; (2) the scientific...
Matching requirements
This program has no statutory formula.
Matching requirements are not applicable to this assistance listing.
MOE requirements are not applicable to this assistance listing.
Examples of funded projects
Not Applicable.
Program listing on SAM.gov
About the program (93.855)
Allergy and Infectious Diseases Research — National Institutes of Allergy and Infectious Diseases
How applications are judged
The major elements in evaluating proposals include assessments of: (1) The scientific merit and general significance of the proposed study and its objectives; (2) the technical adequacy of the experimental design and approach; (3) the competency of the proposed investigator or group to successfully pursue the project; (4) the adequacy of the available and proposed facilities and resources; (5) the necessity of the budget components requested in relation to the proposed project; and (6) the relevance and importance to announced program objectives. The following criteria will be used in considering the scientific and technical merit of SBIR/STTR Phase I grant applications: (1) The soundness and technical merit of the proposed approach; (2) the qualifications of the proposed principal investigator, supporting staff, and consultants; (3) the technological innovation of the proposed research; (4) the potential of the proposed research for commercial application; (5) the appropriateness of the budget requested; (6) the adequacy and suitability of the facilities and research environment; and (7) where applicable, the adequacy of assurances detailing the proposed means for (a) safeguarding human or animal subjects, and/or (b) protecting against or minimizing any adverse effect on the environment. Phase II grant applications will be reviewed based upon the following criteria: (1) The degree to which the Phase I objectives were met and feasibility demonstrated; (2) the...
Matching requirements
This program has no statutory formula.
Matching requirements are not applicable to this assistance listing.
MOE requirements are not applicable to this assistance listing.
Examples of funded projects
Not Applicable.
Program listing on SAM.gov
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