Limited Competition: HEAL Initiative Resource Centers for the Pain Management Effectiveness Network (ERN) (Clinical Trial Not Allowed)

The National Center for Advancing Translational Sciences (NCATS), with NINDS, NIA, NIDCR, NCCIH, NCI, NIAMS, NHLBI, NICHD and the NIH Helping to End Addiction Long-term (HEAL) Initiative seeks to advance its mission by renewing the HEAL Pain Management Effectiveness Research Network (ERN) Resource Centers (RCs) needed for the successful planning, implementation, and completion of rigorous large-scale multisite clinical trials (CTs). CTs will expand the suite of evidence-based effective strategies and therapeutics to alleviate pain across the continuum of acute to chronic pain associated with many types of diseases and conditions, or presenting as a disease itself. The RCs will continue the provision of CT operational expertise, clinical coordination and safety monitoring, data coordination and biostatistical resources, and recruitment and retention support as well as access to additional clinical recruitment sites for CTs with a shared common theme of improving pain management. RCs work within the broad consortium of NCATS Clinical and Translational Science Awards (CTSA) hubs that each may contain multiple clinical sites at different institutions, to implement studies. Grant authorities that allow NCATS and HEAL to forecast this opportunity are 42 U.S.C 241, 284, and 247d. This is a forecast for a limited competition Notice of Funding Opportunity (NOFO) that will invite application(s) from eligible organizations to apply. Application(s) will be peer-reviewed and only funded if meritorious.

This a limited competition. Only award recipients funded under RFA-TR-22-012 are eligible to apply.

The major elements in evaluating proposals include assessments of: (1) The scientific merit and general significance of the proposed study and its objectives; (2) the technical adequacy of the experimental design and approach; (3) the competency of the proposed investigator or group to successfully pursue the project; (4) the adequacy of the available and proposed facilities and resources; (5) the necessity of the budget components requested in relation to the proposed project; and (6) the relevance and importance to announced program objectives and (7) the availability of funds.

This program has no statutory formula. Matching requirements are not applicable to this assistance listing. MOE requirements are not applicable to this assistance listing.

Not Applicable.