National Institutes of Health · Department of Health and Human Services
GREGoRi Innovation Projects (U01 Clinical Trial Optional)
Key facts
- Deadline
- Due Oct 30, 2026 · 24 days left
- Award size
- $3 – $500K
- Total available
- $7.5M · about 10 awards
- Cost share / match
- Not required
- Who can apply
- Private college or university, Small business, Nonprofit without 501(c)(3), State government, Larger business, School district, Other (see eligibility), County government, Special district (utility, fire, etc.), Nonprofit with 501(c)(3), Public college or university, City or town government, Tribal government, Tribal organization
- Where
- Anywhere in the U.S., including Tennessee
Before you apply: federal grants require an active SAM.gov registration (Unique Entity ID) and a Grants.gov account. The deadline is in 24 days. If your registration isn't already active, it may not be ready in time, so check it today. Grant-ready checklist
How this fits you
- Available in Tennessee (nationwide program)
- No cost share required
- Tennessee recipients since 2023: 23
Tell us who you are to see whether you're eligible.
Read the official notice View on Grants.gov Add deadline to my calendar
About this grant
The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. This Notice of Funding Opportunity is intended to stimulate the development and testing of highly innovative experimental or computational approaches for rare disease diagnosis, that have the potential to make transformative improvements to the current state of the art.
Eligibility (from the notice)
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Who in Tennessee has won this program
23 awards to Tennessee recipients in 2 counties since federal FY2023. Largest shown:
| Recipient | Where | Amount | FY |
|---|---|---|---|
| Vanderbilt University Medical Center | Nashville, Davidson County | $16.8M | 2020 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $8.1M | 2016 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $8M | 2018 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $7M | 2020 |
| St Jude Children'S Research Hospital Inc | Memphis, Shelby County | $5.2M | 2018 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $4.6M | 2022 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $4.5M | 2023 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $4.4M | 2024 |
| Vanderbilt University | Nashville, Davidson County | $4.3M | 2016 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $4.3M | 2022 |
| Meharry Medical College | Nashville, Davidson County | $4.2M | 2023 |
| Vanderbilt University Medical Center | Nashville, Davidson County | $3.3M | 2017 |
Source: USAspending.gov. Past awards show who this program funds; they don't guarantee future awards.
About the program (93.172)
Human Genome Research — National Human Genome Research Institute
How applications are judged
Criteria for selecting proposals is described at the NOFO level.
Matching requirements
This program has no statutory formula.
Matching requirements are not applicable to this assistance listing.
MOE requirements are not applicable to this assistance listing.
Examples of funded projects
Fiscal Year2025: Examples of research supported by NHGRI in FY 2025 include characterization of genes, sequencing, databases, and projects on the following list: https://reporter.nih.gov/search/KP6XtPborUWv7kYNeFlJSA/projects?shared=trueFiscal Year2026: Current projects supported by NHGRI include basic genomic science; functional and clinical variation; genomic medicine; technology development; computational genomics and data science; training programs; conferences; databases; determining the ethical, legal, and social implications (ELSI) of biomedical and behavioral research; as well as projects on the following list:
https://reporter.nih.gov/search/PbojAWqEZ0aySDrGRZXHTg/projects?shared=true